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The map label for this gene is ppa [H]

Identifier: 190571204

GI number: 190571204

Start: 882783

End: 883289

Strand: Direct

Name: ppa [H]

Synonym: WPa_0802

Alternate gene names: 190571204

Gene position: 882783-883289 (Clockwise)

Preceding gene: 190571203

Following gene: 190571205

Centisome position: 59.55

GC content: 34.32

Gene sequence:

>507_bases
ATGGATTTAAGCAAAGTAACAACAAAACCAGATGAAATAAATGTAGTAATTGAAATAAGTGCAAATGCTGAGCCTGTAAA
GTATGAATTTAATAAAGAGCTTGGGTTGTTACAAGTTGACAGATTTTTGTCTACCTCAATGACTTATCCTTGCAATTATG
GGTTTATACCAAATACCTGCGCAGGTGATGGTGACCCTGCGGATGTTTTGGTGCTAACTCAATTTCCTTTAGCGCCTGGA
GTTTTGATATCGGTGCGTCCAGTAGGTGCATTACTTACCAAAGACGAGAAAGGAGAGGATGAAAAAATATTAGCTGTACC
TATCTCCAGTGTTGACAGCTATTATGAGAATATAAAAAACTATTCTGATTTATCTAAAAACTTACTAGATAAAATAGCTC
ATTTCTTTTCTCATTATAAAGATTTAGAAAAGGGAAAAACGGTGACAGTTGGAGAATGGGCTAATGTGGAAAAAGCAAAA
AAAATCATTGAAAAAAGTAGAAATTAG

Upstream 100 bases:

>100_bases
ATGGTCCTATTCAATCATGAATCTCTACTTATGAATGATAAATGTAGCACTTTTAAAGTGTATGCTATATAATATCTTCT
CTTGAATAACGAGGTAATCC

Downstream 100 bases:

>100_bases
TTTGCATTAGAGCTGCTCAGAAAAATATTGTTGTTTTTTATATTGCGGTTAAAAGCATTAGACAGGCAGTAAAGGTCTTG
ATATTATAGTAATAATTTGG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MDLSKVTTKPDEINVVIEISANAEPVKYEFNKELGLLQVDRFLSTSMTYPCNYGFIPNTCAGDGDPADVLVLTQFPLAPG
VLISVRPVGALLTKDEKGEDEKILAVPISSVDSYYENIKNYSDLSKNLLDKIAHFFSHYKDLEKGKTVTVGEWANVEKAK
KIIEKSRN

Sequences:

>Translated_168_residues
MDLSKVTTKPDEINVVIEISANAEPVKYEFNKELGLLQVDRFLSTSMTYPCNYGFIPNTCAGDGDPADVLVLTQFPLAPG
VLISVRPVGALLTKDEKGEDEKILAVPISSVDSYYENIKNYSDLSKNLLDKIAHFFSHYKDLEKGKTVTVGEWANVEKAK
KIIEKSRN
>Mature_168_residues
MDLSKVTTKPDEINVVIEISANAEPVKYEFNKELGLLQVDRFLSTSMTYPCNYGFIPNTCAGDGDPADVLVLTQFPLAPG
VLISVRPVGALLTKDEKGEDEKILAVPISSVDSYYENIKNYSDLSKNLLDKIAHFFSHYKDLEKGKTVTVGEWANVEKAK
KIIEKSRN

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=163, Percent_Identity=56.441717791411, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18672; Mature: 18672

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSKVTTKPDEINVVIEISANAEPVKYEFNKELGLLQVDRFLSTSMTYPCNYGFIPNTC
CCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
AGDGDPADVLVLTQFPLAPGVLISVRPVGALLTKDEKGEDEKILAVPISSVDSYYENIKN
CCCCCCCEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCCEEEEEEHHHHHHHHHHHHH
YSDLSKNLLDKIAHFFSHYKDLEKGKTVTVGEWANVEKAKKIIEKSRN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDLSKVTTKPDEINVVIEISANAEPVKYEFNKELGLLQVDRFLSTSMTYPCNYGFIPNTC
CCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
AGDGDPADVLVLTQFPLAPGVLISVRPVGALLTKDEKGEDEKILAVPISSVDSYYENIKN
CCCCCCCEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCCEEEEEEHHHHHHHHHHHHH
YSDLSKNLLDKIAHFFSHYKDLEKGKTVTVGEWANVEKAKKIIEKSRN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]