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The map label for this gene is gap [H]

Identifier: 190570615

GI number: 190570615

Start: 163779

End: 164750

Strand: Reverse

Name: gap [H]

Synonym: WPa_0156

Alternate gene names: 190570615

Gene position: 164750-163779 (Counterclockwise)

Preceding gene: 190570616

Following gene: 190570614

Centisome position: 11.11

GC content: 37.76

Gene sequence:

>972_bases
ATGACAATTCGTGTAGGAATTAATGGTCTTGGTAGAATAGGCAGAAGTGTATTGCGTGCTATTTTTGAAGTAGAAAACTA
TAGCGAGCAAATAGAAGTTGTGGCGGTAAATGGGTCACTCAGTGCTGAGCAGCATGCACATTTGATTAAATATGACTCTG
TTCATGGCAAATTTAACGGCGATATTGATTTTAACGAGTCTGAAAATTGGCTATCTATAAATAGCAGGAAATTTTCTTTA
TATAGAGAACGTAGCCCTGAAAATATTCCTTGGAATGTTGATGTAGTACTTGAATGCACTGGTGCATTCAACAAGCGTGC
GGAAGCAGCAAAGCATAATGCAGAGAGAGTAATTGTCTCTGCTCCAGTTTCAGATGCTGATGTAACTGTAGTTTACGGCG
TAAATAACGATATGCTAAAAAAGGAGCATAAAGTGATCTCAGCAGGTTCTTGTACTACAAACTGTCTGGCTCCGATTGTA
CACATTTTACACTCCAATTTAGGTATAAAAAGCGGTTTTATGACCACTATACATGCCTATACGAATGATCAAAATATTCT
TGATGGCAACCATAGAGACTTACGTAGGGCAAGAGCTTGTGGCCTTTCTATGGTGCCAACTACAACTGGAGCAGCAAAAA
CAATTGGTTCTGTTATTCCTGAGTTAAAGGGTAAGCTAGATGGTACTGCTATTAGAGTTCCGGTTAGCAACGTTTCTATG
GTTGATTTTAAATTTTTAGCTGATAAGAGAGCAACAACTAAGGAAATAAACGAAATATTTAAGAATTCAGCAAATCATGT
GCTTTCCGTATGTAACGAGCCTTTAGTTTCAATAGACTTTGTCCATAACCCTTATAGTGCAATTGTGGATTTAGCTGGTA
CATATGTCACAGGTGATATCTGTAGAGTTGCAGCGTGGTACGATAATGAATGGGCTTTTTCACTGAGAATGTTAGATATA
GCTTTATTGTAA

Upstream 100 bases:

>100_bases
TTTAGTCAATCAATATATTATAACATTAGGATTAACAACTAAAAGAATAGAATGAAATATCAGGCAATATTCCGTATAAT
TAAACTTTTAAGATGGAAAA

Downstream 100 bases:

>100_bases
AGTATGAACGAAAACTCACAAAAATATGCTTCATTTTATGAGCACTTTGCGGAACTTAGAAAAAGGGTTATTTTTTGCTT
TCTATTTTTTTGTGTTACCT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTIRVGINGLGRIGRSVLRAIFEVENYSEQIEVVAVNGSLSAEQHAHLIKYDSVHGKFNGDIDFNESENWLSINSRKFSL
YRERSPENIPWNVDVVLECTGAFNKRAEAAKHNAERVIVSAPVSDADVTVVYGVNNDMLKKEHKVISAGSCTTNCLAPIV
HILHSNLGIKSGFMTTIHAYTNDQNILDGNHRDLRRARACGLSMVPTTTGAAKTIGSVIPELKGKLDGTAIRVPVSNVSM
VDFKFLADKRATTKEINEIFKNSANHVLSVCNEPLVSIDFVHNPYSAIVDLAGTYVTGDICRVAAWYDNEWAFSLRMLDI
ALL

Sequences:

>Translated_323_residues
MTIRVGINGLGRIGRSVLRAIFEVENYSEQIEVVAVNGSLSAEQHAHLIKYDSVHGKFNGDIDFNESENWLSINSRKFSL
YRERSPENIPWNVDVVLECTGAFNKRAEAAKHNAERVIVSAPVSDADVTVVYGVNNDMLKKEHKVISAGSCTTNCLAPIV
HILHSNLGIKSGFMTTIHAYTNDQNILDGNHRDLRRARACGLSMVPTTTGAAKTIGSVIPELKGKLDGTAIRVPVSNVSM
VDFKFLADKRATTKEINEIFKNSANHVLSVCNEPLVSIDFVHNPYSAIVDLAGTYVTGDICRVAAWYDNEWAFSLRMLDI
ALL
>Mature_322_residues
TIRVGINGLGRIGRSVLRAIFEVENYSEQIEVVAVNGSLSAEQHAHLIKYDSVHGKFNGDIDFNESENWLSINSRKFSLY
RERSPENIPWNVDVVLECTGAFNKRAEAAKHNAERVIVSAPVSDADVTVVYGVNNDMLKKEHKVISAGSCTTNCLAPIVH
ILHSNLGIKSGFMTTIHAYTNDQNILDGNHRDLRRARACGLSMVPTTTGAAKTIGSVIPELKGKLDGTAIRVPVSNVSMV
DFKFLADKRATTKEINEIFKNSANHVLSVCNEPLVSIDFVHNPYSAIVDLAGTYVTGDICRVAAWYDNEWAFSLRMLDIA
LL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=39.1566265060241, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=38.855421686747, Blast_Score=224, Evalue=1e-58,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=41.0179640718563, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=40.0602409638554, Blast_Score=237, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=39.7014925373134, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=39.5833333333333, Blast_Score=227, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=40.1785714285714, Blast_Score=216, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=40.1785714285714, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=38.368580060423, Blast_Score=242, Evalue=7e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=39.2749244712991, Blast_Score=241, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=38.0664652567976, Blast_Score=240, Evalue=3e-64,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=39.3939393939394, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=39.3939393939394, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=39.6969696969697, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=39.6969696969697, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=38.0664652567976, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35559; Mature: 35428

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVGINGLGRIGRSVLRAIFEVENYSEQIEVVAVNGSLSAEQHAHLIKYDSVHGKFNG
CEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHEEEEEECCCCEECC
DIDFNESENWLSINSRKFSLYRERSPENIPWNVDVVLECTGAFNKRAEAAKHNAERVIVS
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEE
APVSDADVTVVYGVNNDMLKKEHKVISAGSCTTNCLAPIVHILHSNLGIKSGFMTTIHAY
CCCCCCCEEEEEECCCHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TNDQNILDGNHRDLRRARACGLSMVPTTTGAAKTIGSVIPELKGKLDGTAIRVPVSNVSM
ECCCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
VDFKFLADKRATTKEINEIFKNSANHVLSVCNEPLVSIDFVHNPYSAIVDLAGTYVTGDI
EEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCEEECCC
CRVAAWYDNEWAFSLRMLDIALL
EEEEEEECCCEEEEEEEEEEECC
>Mature Secondary Structure 
TIRVGINGLGRIGRSVLRAIFEVENYSEQIEVVAVNGSLSAEQHAHLIKYDSVHGKFNG
EEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHEEEEEECCCCEECC
DIDFNESENWLSINSRKFSLYRERSPENIPWNVDVVLECTGAFNKRAEAAKHNAERVIVS
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEE
APVSDADVTVVYGVNNDMLKKEHKVISAGSCTTNCLAPIVHILHSNLGIKSGFMTTIHAY
CCCCCCCEEEEEECCCHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TNDQNILDGNHRDLRRARACGLSMVPTTTGAAKTIGSVIPELKGKLDGTAIRVPVSNVSM
ECCCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
VDFKFLADKRATTKEINEIFKNSANHVLSVCNEPLVSIDFVHNPYSAIVDLAGTYVTGDI
EEEEEHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCEEECCC
CRVAAWYDNEWAFSLRMLDIALL
EEEEEEECCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]