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The map label for this gene is znuA [H]

Identifier: 190570607

GI number: 190570607

Start: 151641

End: 152516

Strand: Reverse

Name: znuA [H]

Synonym: WPa_0145

Alternate gene names: 190570607

Gene position: 152516-151641 (Counterclockwise)

Preceding gene: 190570610

Following gene: 190570603

Centisome position: 10.29

GC content: 31.62

Gene sequence:

>876_bases
ATGAGACATTTACTGTTTTTTTTTCTATTACTTTCATTTACATTATACTACAATAGTGCCTTTTCATCCAATTTAAAAAT
TGTAGCTACAATCAAACCTATACACTCACTTGTAGCTTCTGTTACAGATGGAATTTCAAAGCCAGAACTACTAATGTACG
AAGTAGTGTCTGAACATAACTACATGCTCAGGCCTTCAGACGCAAGTAAATTAGAATCTAGCAATATTATATTTTATATC
GATGATTCTTTGGAAACATTCATTAAAACTTTCGCTAAAGAAAATAAGAAGTTAATACCGCTATCAAGTGCAATCGATCT
ACTTCCTGCTCGAACACATTCATTTTCTAGTCACATTCAAGATGAAAAAGATTTGCATATTTGGCTGAGTCCTGAAAATG
CAAAAAGTATGATACTTTCTATCAGTGCAACATTATCTAATATAGATAAAGAAAATGCCTATCGATACAATACTAACGCA
GAGGAGGCTATAAGAAAGATAGACCAAGAAGTAGAAAAAATTACGAAAGAATTGGATGAGTTAAAAAATCAAAAATACAT
AGTTACTCACGATGCTTATCAATATTTCGAAAAATATTTTGATTTAAGTTACCCAAGCGCCATTCTTTCTATAGAAGAAG
ATTCTTACATAGGTATGAAGAGTTTAATGAAATTAAAAAAGGTAATGAAAGAGGAAAACGTTAAATGTATTGTTTCTCAT
TCACGAGAGGATAGCATAAAGCCTAATGTCTTTTCTAGTGACGTAAAAATGGTGATTCTTGATCCTATTGGATCAGATGT
AGAGCCTGGAAAGGATGCATATCTAGATATAATCAGCAGCATTGCACAAAATTTCAAGTCTTGTTTCACTGAGTAA

Upstream 100 bases:

>100_bases
TTTTGTTACCGTATGAAAGAGTAAGGTTTTCTATTTTTAGAATGCAGTTATTGACACTACTTAATTTTTTGGCAAAAATT
GACTTCTTCTCAACATTTAT

Downstream 100 bases:

>100_bases
TGAGTTCTTTTATCTATTCAGATAGCATTGCAAACTTAGTGCTTTCTATTCCAATCACAACTATACCGACATTATCTACC
AGAAGTATATCATCCCAGTC

Product: Putative cation ABC transporter, periplasmic cation-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRHLLFFFLLLSFTLYYNSAFSSNLKIVATIKPIHSLVASVTDGISKPELLMYEVVSEHNYMLRPSDASKLESSNIIFYI
DDSLETFIKTFAKENKKLIPLSSAIDLLPARTHSFSSHIQDEKDLHIWLSPENAKSMILSISATLSNIDKENAYRYNTNA
EEAIRKIDQEVEKITKELDELKNQKYIVTHDAYQYFEKYFDLSYPSAILSIEEDSYIGMKSLMKLKKVMKEENVKCIVSH
SREDSIKPNVFSSDVKMVILDPIGSDVEPGKDAYLDIISSIAQNFKSCFTE

Sequences:

>Translated_291_residues
MRHLLFFFLLLSFTLYYNSAFSSNLKIVATIKPIHSLVASVTDGISKPELLMYEVVSEHNYMLRPSDASKLESSNIIFYI
DDSLETFIKTFAKENKKLIPLSSAIDLLPARTHSFSSHIQDEKDLHIWLSPENAKSMILSISATLSNIDKENAYRYNTNA
EEAIRKIDQEVEKITKELDELKNQKYIVTHDAYQYFEKYFDLSYPSAILSIEEDSYIGMKSLMKLKKVMKEENVKCIVSH
SREDSIKPNVFSSDVKMVILDPIGSDVEPGKDAYLDIISSIAQNFKSCFTE
>Mature_291_residues
MRHLLFFFLLLSFTLYYNSAFSSNLKIVATIKPIHSLVASVTDGISKPELLMYEVVSEHNYMLRPSDASKLESSNIIFYI
DDSLETFIKTFAKENKKLIPLSSAIDLLPARTHSFSSHIQDEKDLHIWLSPENAKSMILSISATLSNIDKENAYRYNTNA
EEAIRKIDQEVEKITKELDELKNQKYIVTHDAYQYFEKYFDLSYPSAILSIEEDSYIGMKSLMKLKKVMKEENVKCIVSH
SREDSIKPNVFSSDVKMVILDPIGSDVEPGKDAYLDIISSIAQNFKSCFTE

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=295, Percent_Identity=25.4237288135593, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33316; Mature: 33316

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLLFFFLLLSFTLYYNSAFSSNLKIVATIKPIHSLVASVTDGISKPELLMYEVVSEHN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
YMLRPSDASKLESSNIIFYIDDSLETFIKTFAKENKKLIPLSSAIDLLPARTHSFSSHIQ
CEECCCCHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHCC
DEKDLHIWLSPENAKSMILSISATLSNIDKENAYRYNTNAEEAIRKIDQEVEKITKELDE
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
LKNQKYIVTHDAYQYFEKYFDLSYPSAILSIEEDSYIGMKSLMKLKKVMKEENVKCIVSH
HCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEC
SREDSIKPNVFSSDVKMVILDPIGSDVEPGKDAYLDIISSIAQNFKSCFTE
CCCCCCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRHLLFFFLLLSFTLYYNSAFSSNLKIVATIKPIHSLVASVTDGISKPELLMYEVVSEHN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
YMLRPSDASKLESSNIIFYIDDSLETFIKTFAKENKKLIPLSSAIDLLPARTHSFSSHIQ
CEECCCCHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHCC
DEKDLHIWLSPENAKSMILSISATLSNIDKENAYRYNTNAEEAIRKIDQEVEKITKELDE
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
LKNQKYIVTHDAYQYFEKYFDLSYPSAILSIEEDSYIGMKSLMKLKKVMKEENVKCIVSH
HCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEC
SREDSIKPNVFSSDVKMVILDPIGSDVEPGKDAYLDIISSIAQNFKSCFTE
CCCCCCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA