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The map label for this gene is rnd [H]

Identifier: 190570587

GI number: 190570587

Start: 126432

End: 127616

Strand: Reverse

Name: rnd [H]

Synonym: WPa_0122

Alternate gene names: 190570587

Gene position: 127616-126432 (Counterclockwise)

Preceding gene: 190570588

Following gene: 190570585

Centisome position: 8.61

GC content: 33.16

Gene sequence:

>1185_bases
ATGCTAATTAGTACGACATCGGAGCTGGAGAATGCATGTGAAGAATTGATGGCAAAAGATCCAAAATTTATAGCAGTGGA
CACAGAGTTTATTAGAAACAATTTAACCTACTATCCTAGATTATCACTAATTCAAATTTCTTACGGAGAGAAGAGTTTTA
TTGTAGATGTGTTAGTACCGGGAATTGACTTATCGCTTATTAAGAAAATAATGCTGAATCGAGAAATAACCAAAGTTTTT
CATAGTTGTCGGCAAGACATAGAATCCTTACTCACCGTGCTTAAATGTGTTCCTACTCCCATTTTTGATACCCAAGTTGC
TGCTATGTTTTGTCATTATTATCACGACTTTATTGGTTATTCAAAAGTAGTAGAGCAATATCAGGGGGTAGCGCTGGATA
AAATTAAAGCTAAAAATTCAGATTGGTTAAAACGGCCATTATCTGAGGATCAATTAGATTATGCAGTAAATGACGTGATA
CACCTATATGACCTACACCAAATATTGTGCAATAAACTTGAAGAAAATAATAGGATGGGCTGGTTTCAAGAAGAGATGGA
ATCAATAGTTGATGTCAATAAGTATTTGCATAATCCAAAAGATGCATGGAAGAGGATTAAATTTAATTATGAAGCAAATC
CAAGGTTGATGTTAACTGTTAAAGCAGTTAGTGAGTGGCAAGAGACCTTAGCACAGCGTTACAATATAAATCGTAATAAG
GTAGTCAATAATGCCGTAATAACTGGTTTAATTGAAAAAAACGTGGAACATATTGATGACATTTTAGATGACCTTAAGAG
AAACACAAAAAATATAAAAGAGGAAGATTTATTAGAATTTATAGATATTTTCAATGAGAATGAGAAGGAATTTGTGCAGC
AAAATTATACTCTGTCGGATAATTATGATAAATCTGTCTTTGATATACTCTCGATTATTTTAGAGAGCAAATGTAAGGAA
AATAACATATCGAGAAAGTTAGTTTCGTCAAAAGATGAGTTAGCTGGATCAATATCTGGGAAGATAGATAAATTGTTCAA
GGGATGGAGATATGATTTTTTCGGCAGATCAGTAGAATCGTTTTTGAATGCAGGCTCAAGGTTTGAAATTTTAATGGTAA
AATCTGCTGATAGTACAGCTAAAATTCGGAGTAATCTTGTGGAGAATAACCGTATCACGTGTTGA

Upstream 100 bases:

>100_bases
TTTACAGAAGGATTAGTTATCATACAGTTGCGTTCTCAATTTCAATCAATTGTAAATATTCAATATAAGTGGTAAAATAT
AGCCACTGAATAAAAAATAT

Downstream 100 bases:

>100_bases
GGTCTAACGAGTTTATTATATCTTTCACTTGAGAAAGAACATTTGCGCTGGTATCGATGATAAAGTCGCTCATTTGCTTT
TTTTCTTCAATAGGGAGCTG

Product: Putative ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLISTTSELENACEELMAKDPKFIAVDTEFIRNNLTYYPRLSLIQISYGEKSFIVDVLVPGIDLSLIKKIMLNREITKVF
HSCRQDIESLLTVLKCVPTPIFDTQVAAMFCHYYHDFIGYSKVVEQYQGVALDKIKAKNSDWLKRPLSEDQLDYAVNDVI
HLYDLHQILCNKLEENNRMGWFQEEMESIVDVNKYLHNPKDAWKRIKFNYEANPRLMLTVKAVSEWQETLAQRYNINRNK
VVNNAVITGLIEKNVEHIDDILDDLKRNTKNIKEEDLLEFIDIFNENEKEFVQQNYTLSDNYDKSVFDILSIILESKCKE
NNISRKLVSSKDELAGSISGKIDKLFKGWRYDFFGRSVESFLNAGSRFEILMVKSADSTAKIRSNLVENNRITC

Sequences:

>Translated_394_residues
MLISTTSELENACEELMAKDPKFIAVDTEFIRNNLTYYPRLSLIQISYGEKSFIVDVLVPGIDLSLIKKIMLNREITKVF
HSCRQDIESLLTVLKCVPTPIFDTQVAAMFCHYYHDFIGYSKVVEQYQGVALDKIKAKNSDWLKRPLSEDQLDYAVNDVI
HLYDLHQILCNKLEENNRMGWFQEEMESIVDVNKYLHNPKDAWKRIKFNYEANPRLMLTVKAVSEWQETLAQRYNINRNK
VVNNAVITGLIEKNVEHIDDILDDLKRNTKNIKEEDLLEFIDIFNENEKEFVQQNYTLSDNYDKSVFDILSIILESKCKE
NNISRKLVSSKDELAGSISGKIDKLFKGWRYDFFGRSVESFLNAGSRFEILMVKSADSTAKIRSNLVENNRITC
>Mature_394_residues
MLISTTSELENACEELMAKDPKFIAVDTEFIRNNLTYYPRLSLIQISYGEKSFIVDVLVPGIDLSLIKKIMLNREITKVF
HSCRQDIESLLTVLKCVPTPIFDTQVAAMFCHYYHDFIGYSKVVEQYQGVALDKIKAKNSDWLKRPLSEDQLDYAVNDVI
HLYDLHQILCNKLEENNRMGWFQEEMESIVDVNKYLHNPKDAWKRIKFNYEANPRLMLTVKAVSEWQETLAQRYNINRNK
VVNNAVITGLIEKNVEHIDDILDDLKRNTKNIKEEDLLEFIDIFNENEKEFVQQNYTLSDNYDKSVFDILSIILESKCKE
NNISRKLVSSKDELAGSISGKIDKLFKGWRYDFFGRSVESFLNAGSRFEILMVKSADSTAKIRSNLVENNRITC

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=379, Percent_Identity=28.4960422163588, Blast_Score=136, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324574, Length=309, Percent_Identity=26.2135922330097, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 45838; Mature: 45838

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISTTSELENACEELMAKDPKFIAVDTEFIRNNLTYYPRLSLIQISYGEKSFIVDVLVP
CCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHCC
GIDLSLIKKIMLNREITKVFHSCRQDIESLLTVLKCVPTPIFDTQVAAMFCHYYHDFIGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKVVEQYQGVALDKIKAKNSDWLKRPLSEDQLDYAVNDVIHLYDLHQILCNKLEENNRMG
HHHHHHHCCCHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WFQEEMESIVDVNKYLHNPKDAWKRIKFNYEANPRLMLTVKAVSEWQETLAQRYNINRNK
CHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHH
VVNNAVITGLIEKNVEHIDDILDDLKRNTKNIKEEDLLEFIDIFNENEKEFVQQNYTLSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCC
NYDKSVFDILSIILESKCKENNISRKLVSSKDELAGSISGKIDKLFKGWRYDFFGRSVES
CCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FLNAGSRFEILMVKSADSTAKIRSNLVENNRITC
HHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLISTTSELENACEELMAKDPKFIAVDTEFIRNNLTYYPRLSLIQISYGEKSFIVDVLVP
CCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHCC
GIDLSLIKKIMLNREITKVFHSCRQDIESLLTVLKCVPTPIFDTQVAAMFCHYYHDFIGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKVVEQYQGVALDKIKAKNSDWLKRPLSEDQLDYAVNDVIHLYDLHQILCNKLEENNRMG
HHHHHHHCCCHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WFQEEMESIVDVNKYLHNPKDAWKRIKFNYEANPRLMLTVKAVSEWQETLAQRYNINRNK
CHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHH
VVNNAVITGLIEKNVEHIDDILDDLKRNTKNIKEEDLLEFIDIFNENEKEFVQQNYTLSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCC
NYDKSVFDILSIILESKCKENNISRKLVSSKDELAGSISGKIDKLFKGWRYDFFGRSVES
CCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FLNAGSRFEILMVKSADSTAKIRSNLVENNRITC
HHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]