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The map label for this gene is dapB

Identifier: 190570574

GI number: 190570574

Start: 113288

End: 114076

Strand: Direct

Name: dapB

Synonym: WPa_0108

Alternate gene names: 190570574

Gene position: 113288-114076 (Clockwise)

Preceding gene: 190570573

Following gene: 190570575

Centisome position: 7.64

GC content: 37.14

Gene sequence:

>789_bases
ATGAAAATCAGAGTTGGAGTAATAGGCTGCTTAGGCAGAATGGGTAAGAAAATACTCAATGAATTAATTACGAATACCAA
AGTGGAAATAGCAGGTGCTGTTGCTCGCTTGGGCAGTGAGTATATAGGCTTAGATATTGGGCCTATTGTAGGCAATAATT
GCAATTTAGGAATCAAAATTACAAGTTCTATTAGTGAGGTATTTGAATCGTCCGATGTTGTAATAGATTTTACAACTAAA
GAATGTATGCTAGAATGCCTTAAGGCGGCCGTGAAATTTAAAAAACCGCTAGTTAGTGGCACAACTGGAATAGAAGGTCT
AAATTTAAAAGACTATGCTGCTAAAGTTCCAATATTATGGTCAGCAAATATGAGTATAGGAGTTAATGTGTTGCTGAAAT
TGGTAAAAGAAGCTGCCAAGCTTTTAGGTAATGAGTATGACGTTGAAATTTGGGAAATGCATCACAATTTAAAAAAGGAT
TCACCATCTGGAACAGCTATAGAGTTTGGTAAAGCAGTTGCTAACGCTGCAAAAGTGGATTTTGAGCTCAATCAATATTC
ACATAATAATTCAAATATAAGAGGGAAAGGAGGAATAGGCTTTGCAGTATCTCGTGGAGGTGGAGTAATAGGAGATCACA
GTGTCATGTTTGTCAATTACGATGAACGAGTAGAATTAAATCACAAGGCAATTGATCGTACAACGTTTGCTAGAGGGGCG
GTTCAGGCAGCAATATGGTTGTGCGAGAATAAAACTCCAGGACTTTATTCAATGCAGGATTTAGTATGA

Upstream 100 bases:

>100_bases
TCGATGTATAGCTATAGTTTTATCAGTGTAAGGCTAAATATGCTAAGCTTATAAAGATGACAAAGCTTCAAAAAAAGCCT
AACATAGTGGAAAAAGCTTT

Downstream 100 bases:

>100_bases
ACGATAAATACGCTTTCGTTAAAAATTTAAATCTTTGGTATGGCTCTAAACAAGTTTTATTCGATATAAATTTGAATATT
TGCAAAAAGAAAGTCACAAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARLGSEYIGLDIGPIVGNNCNLGIKITSSISEVFESSDVVIDFTTK
ECMLECLKAAVKFKKPLVSGTTGIEGLNLKDYAAKVPILWSANMSIGVNVLLKLVKEAAKLLGNEYDVEIWEMHHNLKKD
SPSGTAIEFGKAVANAAKVDFELNQYSHNNSNIRGKGGIGFAVSRGGGVIGDHSVMFVNYDERVELNHKAIDRTTFARGA
VQAAIWLCENKTPGLYSMQDLV

Sequences:

>Translated_262_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARLGSEYIGLDIGPIVGNNCNLGIKITSSISEVFESSDVVIDFTTK
ECMLECLKAAVKFKKPLVSGTTGIEGLNLKDYAAKVPILWSANMSIGVNVLLKLVKEAAKLLGNEYDVEIWEMHHNLKKD
SPSGTAIEFGKAVANAAKVDFELNQYSHNNSNIRGKGGIGFAVSRGGGVIGDHSVMFVNYDERVELNHKAIDRTTFARGA
VQAAIWLCENKTPGLYSMQDLV
>Mature_262_residues
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARLGSEYIGLDIGPIVGNNCNLGIKITSSISEVFESSDVVIDFTTK
ECMLECLKAAVKFKKPLVSGTTGIEGLNLKDYAAKVPILWSANMSIGVNVLLKLVKEAAKLLGNEYDVEIWEMHHNLKKD
SPSGTAIEFGKAVANAAKVDFELNQYSHNNSNIRGKGGIGFAVSRGGGVIGDHSVMFVNYDERVELNHKAIDRTTFARGA
VQAAIWLCENKTPGLYSMQDLV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=38.8679245283019, Blast_Score=180, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_WOLPP (B3CN84)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001974932.1
- EnsemblBacteria:   EBWOLT00000000604
- GeneID:   6384467
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0108
- GeneTree:   EBGT00050000031122
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28317; Mature: 28317

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARLGSEYIGLDIGPIVGNNCNLGIKI
CEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCEEECCEECCCCCEEEEE
TSSISEVFESSDVVIDFTTKECMLECLKAAVKFKKPLVSGTTGIEGLNLKDYAAKVPILW
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEE
SANMSIGVNVLLKLVKEAAKLLGNEYDVEIWEMHHNLKKDSPSGTAIEFGKAVANAAKVD
ECCCCHHHHHHHHHHHHHHHHCCCCCCEEHEEHHHHHCCCCCCCCHHHHHHHHHHHHHEE
FELNQYSHNNSNIRGKGGIGFAVSRGGGVIGDHSVMFVNYDERVELNHKAIDRTTFARGA
EEEECCCCCCCCEECCCCEEEEEECCCCEECCCEEEEEECCCCEECCHHHHHHHHHHHHH
VQAAIWLCENKTPGLYSMQDLV
HEEEEEEECCCCCCCCCHHHCC
>Mature Secondary Structure
MKIRVGVIGCLGRMGKKILNELITNTKVEIAGAVARLGSEYIGLDIGPIVGNNCNLGIKI
CEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCEEECCEECCCCCEEEEE
TSSISEVFESSDVVIDFTTKECMLECLKAAVKFKKPLVSGTTGIEGLNLKDYAAKVPILW
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEE
SANMSIGVNVLLKLVKEAAKLLGNEYDVEIWEMHHNLKKDSPSGTAIEFGKAVANAAKVD
ECCCCHHHHHHHHHHHHHHHHCCCCCCEEHEEHHHHHCCCCCCCCHHHHHHHHHHHHHEE
FELNQYSHNNSNIRGKGGIGFAVSRGGGVIGDHSVMFVNYDERVELNHKAIDRTTFARGA
EEEECCCCCCCCEECCCCEEEEEECCCCEECCCEEEEEECCCCEECCHHHHHHHHHHHHH
VQAAIWLCENKTPGLYSMQDLV
HEEEEEEECCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA