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The map label for this gene is ribH

Identifier: 190570483

GI number: 190570483

Start: 4898

End: 5326

Strand: Direct

Name: ribH

Synonym: WPa_0005

Alternate gene names: 190570483

Gene position: 4898-5326 (Clockwise)

Preceding gene: 190570482

Following gene: 190570484

Centisome position: 0.33

GC content: 33.33

Gene sequence:

>429_bases
ATGTCGAAAATACTAATAGTTAATTCAGTTTATTATACTGAAATAGCAAACCTTTTGCTTGAGGGTGCAACTGATAAATT
CAAAGGAAATAATATTGGTTACGAGATAATTAAAGCGCCTGGTACGTTTGAGATACCAGCTGCAATTCTTTTTGCGGTCA
AAGGCAAGAATACTAATTATGATGGTTATTTAGCTCTTGGATGTGTAATTCGTGGTGAAACTGATCATTATAAATACGTT
TGTAAAGGAGTAATCGAAGGCTTAAATGCAATTGTTATGCATCATGCAATACCTCTTGGTATGGGAATAATCACAGCAGA
TAGTAAAGATAAAGCACTAATTAGAGCTGACAAAAATAAAAAGAACGTTGGTGGCCATGCAGCCTCAACTGTTTTGCATA
TGATAGATCTACACAATAAATTAAAATAA

Upstream 100 bases:

>100_bases
TTTCCTGCCGGCCTGGTAATATATTGGATATTTAGTAATATTATAACTCTGGTTCAACAATCATTAATAAAGTTGCTTTT
AACAAGAAAAGTAGGAATGA

Downstream 100 bases:

>100_bases
TGGAGGAAAAACCAGTAGATAAAAAATGGCGCATAAAAAGAAGTACGGCAAGATTTCTTGCTGTACAAATTGCTTATTCA
AATATTTTTGTAAGTTACAA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSKILIVNSVYYTEIANLLLEGATDKFKGNNIGYEIIKAPGTFEIPAAILFAVKGKNTNYDGYLALGCVIRGETDHYKYV
CKGVIEGLNAIVMHHAIPLGMGIITADSKDKALIRADKNKKNVGGHAASTVLHMIDLHNKLK

Sequences:

>Translated_142_residues
MSKILIVNSVYYTEIANLLLEGATDKFKGNNIGYEIIKAPGTFEIPAAILFAVKGKNTNYDGYLALGCVIRGETDHYKYV
CKGVIEGLNAIVMHHAIPLGMGIITADSKDKALIRADKNKKNVGGHAASTVLHMIDLHNKLK
>Mature_141_residues
SKILIVNSVYYTEIANLLLEGATDKFKGNNIGYEIIKAPGTFEIPAAILFAVKGKNTNYDGYLALGCVIRGETDHYKYVC
KGVIEGLNAIVMHHAIPLGMGIITADSKDKALIRADKNKKNVGGHAASTVLHMIDLHNKLK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=148, Percent_Identity=35.8108108108108, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_WOLPP (B3CL66)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001974841.1
- EnsemblBacteria:   EBWOLT00000000970
- GeneID:   6385245
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0005
- GeneTree:   EBGT00050000031345
- HOGENOM:   HBG311126
- OMA:   SSRALMD
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 15427; Mature: 15296

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILIVNSVYYTEIANLLLEGATDKFKGNNIGYEIIKAPGTFEIPAAILFAVKGKNTNY
CCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCC
DGYLALGCVIRGETDHYKYVCKGVIEGLNAIVMHHAIPLGMGIITADSKDKALIRADKNK
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCC
KNVGGHAASTVLHMIDLHNKLK
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKILIVNSVYYTEIANLLLEGATDKFKGNNIGYEIIKAPGTFEIPAAILFAVKGKNTNY
CEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCC
DGYLALGCVIRGETDHYKYVCKGVIEGLNAIVMHHAIPLGMGIITADSKDKALIRADKNK
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCC
KNVGGHAASTVLHMIDLHNKLK
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA