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The map label for this gene is prsW [H]

Identifier: 18978421

GI number: 18978421

Start: 1891159

End: 1891866

Strand: Reverse

Name: prsW [H]

Synonym: PF2049

Alternate gene names: 18978421

Gene position: 1891866-1891159 (Counterclockwise)

Preceding gene: 18978422

Following gene: 33359592

Centisome position: 99.14

GC content: 40.25

Gene sequence:

>708_bases
ATGTCTCTACTCACCTCTCTAATATTCTTTGCTTATGCTCCTGCTTTAGCCTTACTTTGGTATTTTTACCACGAAGATAA
GCTAGAACCAGAGCCCAAGAAGTACGTTATCTTAACGTTTCTTTTTGGAGCTACTGTGTCTGTAATAATGGCAATTATAA
TTGAGAGCCTTCTAGTTCCCAGCTGGATAACATCCATAGGAGCATTACTCCCAGCAACTTTCTTTTATATCTCCTTAGTT
GCGGGAATCGTTGAGGAGCCGGCCAAGGCTCTTGCTATTAAACTTCCATATAAGGCAAGACAAATGGATGGGATAATGGA
TGGCGTTATCTATGGAGTTGCCGCTGGACTTGGGTTTGCAGCTACGGAAAATCTACTTTATGGTCTTGGTTATGGAATGG
GGACTACAATAGCTAGAGCACTTTTAACTCCCCTAGCCCATGCCTCATGGAGTGCTATAATAGGAGTAGGTTATGGTCTA
AAATCTGAAGGAAAAATTTATGACCTGACTCCTTATTTTGCACTTGCAATATTGTTGCACTTTCTATGGGATTACTTTGC
GTTTCTCTCAACTGTTGTTTCAGCTTATTACATCTTCGTGATCTTAATACTGCTGATAAATATAAGCTTGCTTAGATACT
TTATAATCCTGGGAAAGAGAGAAGATTTGGAGAAGTACTGGTGGATGGGTGGTAGAAGATGGTGGTAA

Upstream 100 bases:

>100_bases
CATCGAAGAACCTTGAAAAGTATCTAGAAAAGGCGGGATGAGGAAGCCGAGGACACCTGATGGATGATGACTCTTCGCTT
CGCCGACCGGTGGTGATTAA

Downstream 100 bases:

>100_bases
AGGAAAAGCTGGAAAAAGCGCTAATAGAAGTGAGACCTTATGTAGAGTATTACAACGAGCTTAAAGCCTTAGTTTCAAAA
ATTTCATCCTCAGTAAATGA

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSLLTSLIFFAYAPALALLWYFYHEDKLEPEPKKYVILTFLFGATVSVIMAIIIESLLVPSWITSIGALLPATFFYISLV
AGIVEEPAKALAIKLPYKARQMDGIMDGVIYGVAAGLGFAATENLLYGLGYGMGTTIARALLTPLAHASWSAIIGVGYGL
KSEGKIYDLTPYFALAILLHFLWDYFAFLSTVVSAYYIFVILILLINISLLRYFIILGKREDLEKYWWMGGRRWW

Sequences:

>Translated_235_residues
MSLLTSLIFFAYAPALALLWYFYHEDKLEPEPKKYVILTFLFGATVSVIMAIIIESLLVPSWITSIGALLPATFFYISLV
AGIVEEPAKALAIKLPYKARQMDGIMDGVIYGVAAGLGFAATENLLYGLGYGMGTTIARALLTPLAHASWSAIIGVGYGL
KSEGKIYDLTPYFALAILLHFLWDYFAFLSTVVSAYYIFVILILLINISLLRYFIILGKREDLEKYWWMGGRRWW
>Mature_234_residues
SLLTSLIFFAYAPALALLWYFYHEDKLEPEPKKYVILTFLFGATVSVIMAIIIESLLVPSWITSIGALLPATFFYISLVA
GIVEEPAKALAIKLPYKARQMDGIMDGVIYGVAAGLGFAATENLLYGLGYGMGTTIARALLTPLAHASWSAIIGVGYGLK
SEGKIYDLTPYFALAILLHFLWDYFAFLSTVVSAYYIFVILILLINISLLRYFIILGKREDLEKYWWMGGRRWW

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26354; Mature: 26222

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLTSLIFFAYAPALALLWYFYHEDKLEPEPKKYVILTFLFGATVSVIMAIIIESLLVP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWITSIGALLPATFFYISLVAGIVEEPAKALAIKLPYKARQMDGIMDGVIYGVAAGLGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ATENLLYGLGYGMGTTIARALLTPLAHASWSAIIGVGYGLKSEGKIYDLTPYFALAILLH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHH
FLWDYFAFLSTVVSAYYIFVILILLINISLLRYFIILGKREDLEKYWWMGGRRWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLLTSLIFFAYAPALALLWYFYHEDKLEPEPKKYVILTFLFGATVSVIMAIIIESLLVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWITSIGALLPATFFYISLVAGIVEEPAKALAIKLPYKARQMDGIMDGVIYGVAAGLGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ATENLLYGLGYGMGTTIARALLTPLAHASWSAIIGVGYGLKSEGKIYDLTPYFALAILLH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHH
FLWDYFAFLSTVVSAYYIFVILILLINISLLRYFIILGKREDLEKYWWMGGRRWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA