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The map label for this gene is btuR [H]

Identifier: 18978410

GI number: 18978410

Start: 1881861

End: 1882388

Strand: Direct

Name: btuR [H]

Synonym: PF2038

Alternate gene names: 18978410

Gene position: 1881861-1882388 (Clockwise)

Preceding gene: 18978409

Following gene: 18978414

Centisome position: 98.62

GC content: 44.51

Gene sequence:

>528_bases
ATGAGTTGGAAAGAAAAGCTTGGTTTAGTTCATATCTACACTGGAAATGGAAAAGGGAAAACCACAGCAGCCCTAGGCTT
AGCGCTGAGAATGCTCGGCTCTGGGGGGAAGGTAATAATAGTCCAATTCCTTAAGGCTCCAAAAGTGTACGGAGAGTATG
AGATGGCCCAAAAGTGTGGATTCACGATTGAATCTTACGGCCTTCCAAAGTTTGTTCATGGAAAGCCGGATGAAGAGGAC
ATAAAAGCCGCAAAGAAGGCCCTTGAAAGGGCCAAAGAAGTCGTGAAGAGTGGCGAATGGGATCTTGTAATTCTAGATGA
AATATGCGTGGCCCTTGGCTTTGGAATGATATCAATTGAGGAAGTCAAGGAGCTCATTCTAAACAAGGCCAAAAACACTG
AGCTCGTTCTCACTGGAAGATACTGCCCAGAGGAGCTCTTTGAGCTTGCAGACTATGTTACCGAAATGAAAGAAGTAAAG
CACCCATACCAAAGAGGAATACTGGCAAGAAGGGGAATTGAGTATTAA

Upstream 100 bases:

>100_bases
CCTCAAGATTTAAAATTTAAACTCTCAAAGTCTTATAGCTCCGATGATGAGTCTCGCTCGGCTGATAGATGATGTAGGGC
ATACTGGCTGAGGTGATAGT

Downstream 100 bases:

>100_bases
TCTTCTTCCCTTTTCTCCATTATTATTACATAGTCGGCCGCATTCTGAAGAGCCACAGCGAACCCAGGTTCAACACCTAT
AACTACCGTCTCTTTCCCCC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSWKEKLGLVHIYTGNGKGKTTAALGLALRMLGSGGKVIIVQFLKAPKVYGEYEMAQKCGFTIESYGLPKFVHGKPDEED
IKAAKKALERAKEVVKSGEWDLVILDEICVALGFGMISIEEVKELILNKAKNTELVLTGRYCPEELFELADYVTEMKEVK
HPYQRGILARRGIEY

Sequences:

>Translated_175_residues
MSWKEKLGLVHIYTGNGKGKTTAALGLALRMLGSGGKVIIVQFLKAPKVYGEYEMAQKCGFTIESYGLPKFVHGKPDEED
IKAAKKALERAKEVVKSGEWDLVILDEICVALGFGMISIEEVKELILNKAKNTELVLTGRYCPEELFELADYVTEMKEVK
HPYQRGILARRGIEY
>Mature_174_residues
SWKEKLGLVHIYTGNGKGKTTAALGLALRMLGSGGKVIIVQFLKAPKVYGEYEMAQKCGFTIESYGLPKFVHGKPDEEDI
KAAKKALERAKEVVKSGEWDLVILDEICVALGFGMISIEEVKELILNKAKNTELVLTGRYCPEELFELADYVTEMKEVKH
PYQRGILARRGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=174, Percent_Identity=33.9080459770115, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19570; Mature: 19439

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKEKLGLVHIYTGNGKGKTTAALGLALRMLGSGGKVIIVQFLKAPKVYGEYEMAQKCG
CCHHHHHCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHC
FTIESYGLPKFVHGKPDEEDIKAAKKALERAKEVVKSGEWDLVILDEICVALGFGMISIE
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCHH
EVKELILNKAKNTELVLTGRYCPEELFELADYVTEMKEVKHPYQRGILARRGIEY
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SWKEKLGLVHIYTGNGKGKTTAALGLALRMLGSGGKVIIVQFLKAPKVYGEYEMAQKCG
CHHHHHCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHC
FTIESYGLPKFVHGKPDEEDIKAAKKALERAKEVVKSGEWDLVILDEICVALGFGMISIE
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCHH
EVKELILNKAKNTELVLTGRYCPEELFELADYVTEMKEVKHPYQRGILARRGIEY
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]