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The map label for this gene is lacF [H]

Identifier: 18978340

GI number: 18978340

Start: 1817213

End: 1818067

Strand: Direct

Name: lacF [H]

Synonym: PF1968

Alternate gene names: 18978340

Gene position: 1817213-1818067 (Clockwise)

Preceding gene: 18978339

Following gene: 18978341

Centisome position: 95.23

GC content: 41.4

Gene sequence:

>855_bases
ATGAAAATAAGAAGTTCTCATATTCCCTACCTTTTAATTTTACCGGCCGTGGCTTACCTAGCGTTTTTCATTGGCTATCC
TCTGATTCAAGCCCTTTACCTAGCTTTCACTAAGAATGGCGCGTTTTCATTGGATACAGTTAGGAGAGCCACTTCTGATC
CAATGTTTTGGCAGGCGCTAAAATATACAATTCTACTGGCTATAACCATAGTTCCCCTCCAACTTATCCTCGCATTGATA
CTGGCTTTGGCCGTTAATGGGTCATTTAAAGGAAGAGATTTCGCTATATACGCCCTAGTTATACCTTTAACGATAAGTGA
TGTAGCCGCTGGCTTGATTTGGTATACAATGCTTGCCGATTATGGATTTTTAAATAAGCTTCTCTTGAACCTGGGATTAA
TTTCAGAACCAATTCACTTCTTCGGGTATGAATATAGGATGATGGAATTCCTAGCCATAGTTATTGCAGAAGTTTGGAGA
GCTACTGCCATAGTCTTCGTAATTTTGGTTGCAGGACTTCAAATGATAAGTAAGGAGTATCTAGAGGCTGCTGAAGTTTT
TGGAGCTGGCTACTGGACAAGACTTAGGAAAATAGTAATTCCAATGCTAAAGCCCAGCATTCAAAGCGCCCTCATTATTA
GAACGCTCTTCGCCATGCAGGTCTTCGGTATTGTCTGGATATTAGCGGGAAGAGACATCCCAGTGTTGGCCGGAGAGGGA
TTCTATCAATTGGTGGAGATAAAGGATTATGGAGTGGCCTCAATATACGCCTTAACAATAGCTGCATTATCAATACTCCT
CGGAGCATTGTACATTAAGTTCCTGAAAGCTGAATATCTGGAGGTGAGAACATGA

Upstream 100 bases:

>100_bases
TGAAAGAGTTGGGTCCAAAGCTTCACAAACTCTTTGAAGAGGTAGGAGTTCCAGAGCCTTGATTTTATTCCCTTTTTTCT
TTCTTTTTAGGTGATGGGCA

Downstream 100 bases:

>100_bases
ACGAGAAAACACTTTTTATGCTTAAAAAAGTCCTATTTTATGCGTTCATCTTTACCGTCGTTGCCTGGATAATAATTCCC
CTCATTGTTTCAGCCCTCTA

Product: sugar transport membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKIRSSHIPYLLILPAVAYLAFFIGYPLIQALYLAFTKNGAFSLDTVRRATSDPMFWQALKYTILLAITIVPLQLILALI
LALAVNGSFKGRDFAIYALVIPLTISDVAAGLIWYTMLADYGFLNKLLLNLGLISEPIHFFGYEYRMMEFLAIVIAEVWR
ATAIVFVILVAGLQMISKEYLEAAEVFGAGYWTRLRKIVIPMLKPSIQSALIIRTLFAMQVFGIVWILAGRDIPVLAGEG
FYQLVEIKDYGVASIYALTIAALSILLGALYIKFLKAEYLEVRT

Sequences:

>Translated_284_residues
MKIRSSHIPYLLILPAVAYLAFFIGYPLIQALYLAFTKNGAFSLDTVRRATSDPMFWQALKYTILLAITIVPLQLILALI
LALAVNGSFKGRDFAIYALVIPLTISDVAAGLIWYTMLADYGFLNKLLLNLGLISEPIHFFGYEYRMMEFLAIVIAEVWR
ATAIVFVILVAGLQMISKEYLEAAEVFGAGYWTRLRKIVIPMLKPSIQSALIIRTLFAMQVFGIVWILAGRDIPVLAGEG
FYQLVEIKDYGVASIYALTIAALSILLGALYIKFLKAEYLEVRT
>Mature_284_residues
MKIRSSHIPYLLILPAVAYLAFFIGYPLIQALYLAFTKNGAFSLDTVRRATSDPMFWQALKYTILLAITIVPLQLILALI
LALAVNGSFKGRDFAIYALVIPLTISDVAAGLIWYTMLADYGFLNKLLLNLGLISEPIHFFGYEYRMMEFLAIVIAEVWR
ATAIVFVILVAGLQMISKEYLEAAEVFGAGYWTRLRKIVIPMLKPSIQSALIIRTLFAMQVFGIVWILAGRDIPVLAGEG
FYQLVEIKDYGVASIYALTIAALSILLGALYIKFLKAEYLEVRT

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=186, Percent_Identity=27.9569892473118, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31767; Mature: 31767

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRSSHIPYLLILPAVAYLAFFIGYPLIQALYLAFTKNGAFSLDTVRRATSDPMFWQAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCHHHHHHH
KYTILLAITIVPLQLILALILALAVNGSFKGRDFAIYALVIPLTISDVAAGLIWYTMLAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YGFLNKLLLNLGLISEPIHFFGYEYRMMEFLAIVIAEVWRATAIVFVILVAGLQMISKEY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAAEVFGAGYWTRLRKIVIPMLKPSIQSALIIRTLFAMQVFGIVWILAGRDIPVLAGEG
HHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
FYQLVEIKDYGVASIYALTIAALSILLGALYIKFLKAEYLEVRT
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRSSHIPYLLILPAVAYLAFFIGYPLIQALYLAFTKNGAFSLDTVRRATSDPMFWQAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCHHHHHHH
KYTILLAITIVPLQLILALILALAVNGSFKGRDFAIYALVIPLTISDVAAGLIWYTMLAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YGFLNKLLLNLGLISEPIHFFGYEYRMMEFLAIVIAEVWRATAIVFVILVAGLQMISKEY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAAEVFGAGYWTRLRKIVIPMLKPSIQSALIIRTLFAMQVFGIVWILAGRDIPVLAGEG
HHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
FYQLVEIKDYGVASIYALTIAALSILLGALYIKFLKAEYLEVRT
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]