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The map label for this gene is ubiA

Identifier: 18978335

GI number: 18978335

Start: 1813313

End: 1814146

Strand: Reverse

Name: ubiA

Synonym: PF1963

Alternate gene names: NA

Gene position: 1814146-1813313 (Counterclockwise)

Preceding gene: 18978338

Following gene: 18978334

Centisome position: 95.07

GC content: 41.01

Gene sequence:

>834_bases
ATGGAAGTCAAGGGATTCATAGAGATAATGAGACCTCATAATTGTATCCTTGCCGGAATAGTTGGAATTTTGGGAGCATT
GGTGGCCTATGAAGGAATTCCAGACATTAAAACCCTCACATTAATTTTTTGGGTGGTTTACTTTGGATGTTCTGGAGGGA
ACACCGCCAATGATTACTTTGATTATGAAATTGACAAAATAAACAGGCCGAACAGGCCTCTTCCCAGGGGTGCCATGTCC
AGGAGAGCAGCTCTGTACTATGCCCTTCTTCAATATGCTATTGGAAGTATACTCGCTTATTTCCTAAATATAAGGGCTTT
TGTCTTTGCCACAATTGCGTACTTCCTGACGTTCTTATATGGATGGAAGCTCAAACCTCTCCCCCTCGTTGGGAACATAA
CAGTAGCAGCCTTAACGGCGGCAACTCCAATATATGGGGCAATTGGAGTGGGTAGAATAGGATTAGCTGGGTATTTGGCA
ATTTGTGCGTTCCTAGTTAACGTTTCAAGGGAAATAATGAAGGATATTGAAGATATTGAGGGAGACAAAGCTTTAGGAGC
GAGAACCCTTCCCATAATAATAGGAGAGAAGAAAGCTGCAATAATAGCAGCGATTTTTGGATTTCTTACAGTAATAGCTT
CTTTCCTTCCAGTAAAGGTAGGAATAGGTCTTGGGTATGCTCCCATAATAATTGTGGACATTATTATTATAAAAGCAAGC
ATTGATGTTCTTAGAGATCCAAAAGCGGCCAGCAAAGGTCAAAAATTATTGAAAATTGCAACTTTCGTAGCAGTTATAAG
CTTCTTAGCGGGAGCTCTTACTAAGGGGGTGTGA

Upstream 100 bases:

>100_bases
TCCCTACACCTCCAGAAGTAGAGGTTTTTTCTCTAACTGCTAATCGGGTTAGGGATGTTATTTATAAAACTTTTCCTATA
TTTAGATGGGCGAGCAAGAG

Downstream 100 bases:

>100_bases
GTTGTGAAAATAAATGACATCATTAGAGAAAACATTGAGAAGGATGGGCTTTGGCTTGTGATAACTTTTAAGACTCCTTA
TGGGCCAAGAGATACTTTGG

Product: prenyltransferase UbiA-like protein

Products: NA

Alternate protein names: DGGGP synthase; DGGGPS; (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Geranylgeranylglycerol-phosphate geranylgeranyltransferase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEVKGFIEIMRPHNCILAGIVGILGALVAYEGIPDIKTLTLIFWVVYFGCSGGNTANDYFDYEIDKINRPNRPLPRGAMS
RRAALYYALLQYAIGSILAYFLNIRAFVFATIAYFLTFLYGWKLKPLPLVGNITVAALTAATPIYGAIGVGRIGLAGYLA
ICAFLVNVSREIMKDIEDIEGDKALGARTLPIIIGEKKAAIIAAIFGFLTVIASFLPVKVGIGLGYAPIIIVDIIIIKAS
IDVLRDPKAASKGQKLLKIATFVAVISFLAGALTKGV

Sequences:

>Translated_277_residues
MEVKGFIEIMRPHNCILAGIVGILGALVAYEGIPDIKTLTLIFWVVYFGCSGGNTANDYFDYEIDKINRPNRPLPRGAMS
RRAALYYALLQYAIGSILAYFLNIRAFVFATIAYFLTFLYGWKLKPLPLVGNITVAALTAATPIYGAIGVGRIGLAGYLA
ICAFLVNVSREIMKDIEDIEGDKALGARTLPIIIGEKKAAIIAAIFGFLTVIASFLPVKVGIGLGYAPIIIVDIIIIKAS
IDVLRDPKAASKGQKLLKIATFVAVISFLAGALTKGV
>Mature_277_residues
MEVKGFIEIMRPHNCILAGIVGILGALVAYEGIPDIKTLTLIFWVVYFGCSGGNTANDYFDYEIDKINRPNRPLPRGAMS
RRAALYYALLQYAIGSILAYFLNIRAFVFATIAYFLTFLYGWKLKPLPLVGNITVAALTAATPIYGAIGVGRIGLAGYLA
ICAFLVNVSREIMKDIEDIEGDKALGARTLPIIIGEKKAAIIAAIFGFLTVIASFLPVKVGIGLGYAPIIIVDIIIIKAS
IDVLRDPKAASKGQKLLKIATFVAVISFLAGALTKGV

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesi

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. DGGGP synthase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DGGGP_PYRFU (Q8TZM7)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579692.1
- ProteinModelPortal:   Q8TZM7
- EnsemblBacteria:   EBPYRT00000005986
- GeneID:   1469845
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1963
- NMPDR:   fig|186497.1.peg.2015
- GeneTree:   EBGT00050000023060
- HOGENOM:   HBG667825
- OMA:   EVDRIND
- ProtClustDB:   PRK12883
- HAMAP:   MF_01286
- InterPro:   IPR000537

Pfam domain/function: PF01040 UbiA

EC number: =2.5.1.42

Molecular weight: Translated: 29792; Mature: 29792

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe1a24f4)-; HASH(0xd79e750)-; HASH(0xf7a1d14)-; HASH(0xfc1a640)-; HASH(0xf4a772c)-; HASH(0xf8141dc)-; HASH(0xeace530)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKGFIEIMRPHNCILAGIVGILGALVAYEGIPDIKTLTLIFWVVYFGCSGGNTANDYF
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DYEIDKINRPNRPLPRGAMSRRAALYYALLQYAIGSILAYFLNIRAFVFATIAYFLTFLY
CCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWKLKPLPLVGNITVAALTAATPIYGAIGVGRIGLAGYLAICAFLVNVSREIMKDIEDIE
CCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDKALGARTLPIIIGEKKAAIIAAIFGFLTVIASFLPVKVGIGLGYAPIIIVDIIIIKAS
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDVLRDPKAASKGQKLLKIATFVAVISFLAGALTKGV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MEVKGFIEIMRPHNCILAGIVGILGALVAYEGIPDIKTLTLIFWVVYFGCSGGNTANDYF
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DYEIDKINRPNRPLPRGAMSRRAALYYALLQYAIGSILAYFLNIRAFVFATIAYFLTFLY
CCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWKLKPLPLVGNITVAALTAATPIYGAIGVGRIGLAGYLAICAFLVNVSREIMKDIEDIE
CCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDKALGARTLPIIIGEKKAAIIAAIFGFLTVIASFLPVKVGIGLGYAPIIIVDIIIIKAS
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDVLRDPKAASKGQKLLKIATFVAVISFLAGALTKGV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA