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The map label for this gene is xerC [C]

Identifier: 18978240

GI number: 18978240

Start: 1724035

End: 1724895

Strand: Direct

Name: xerC [C]

Synonym: PF1868

Alternate gene names: 18978240

Gene position: 1724035-1724895 (Clockwise)

Preceding gene: 33359578

Following gene: 18978241

Centisome position: 90.35

GC content: 38.68

Gene sequence:

>861_bases
ATGAGGGAGAAAACATTGAGGAGTGAGGTACTAGAGGAATTTGCAACGTATCTTGAGCTAGAAGGAAAGAGCAAGAACAC
GATTAGAATGTACACATACTTCCTCTCTAAATTTTTGGAAGAAGGCTATTCTCCGACAGCAAGAGATGCCCTAAGATTTC
TAGCAAAGTTAAGAGCCAAGGGGTATTCAATTAGGAGCATTAATCTAGTTGTACAAGCCTTAAAGGCCTATTTTAAGTTT
GAAGGACTCAACGAAGAAGCTGAGAGGTTAAGGAATCCAAAAATCCCTAAAACATTACCAAAAAGCCTGACTGAAGAGGA
AGTAAAAAAGTTAATTGAAGTTATTCCAAAGGATAAAATTAGAGATAGACTCATAGTTCTTCTTCTCTATGGAACAGGCC
TAAGAGTTTCCGAGCTCTGCAATCTTAAAATAGAGGATATTAACTTCGAAAAAGGATTTTTAACTGTGAGAGGGGGAAAA
GGTGGAAAAGACAGAACAATCCCAATTCCACAACCCCTCCTAACCGAGATAAAAAATTATCTGAGAAGGAGAACTGATGA
CAGCCCATATTTGTTTGTAGAGAGTAGGAGAAAGAATAAGGAGAAGCTCTCTCCAAAAACTGTGTGGAGAATATTAAAAG
AATATGGGAGAAAAGCAGGAATAAAAGTCACACCTCATCAACTAAGACATAGCTTCGCCACTCACATGCTTGAGAGGGGA
ATAGACATAAGGATAATTCAAGAGCTCCTAGGCCATGCGAGTTTGTCTACAACTCAAATTTACACTAGGGTGACAGCTAA
ACATCTGAAAGAGGCCGTTGAAAGGGCAAACCTATTGGAAAATTTAATTGGAGGTGAGTAA

Upstream 100 bases:

>100_bases
AGCCTACAGCTCACACAATCAATTGAAAGGGAGGAAGAGAACATTGAGGTAATTGAAGGGGAAGAAGAGAAGCTTGAAGA
AGAAGTAGAGGTCATTGAGA

Downstream 100 bases:

>100_bases
ATGCTAATTAGAGCCTTTGTTCCGGCTCATATAACAGCTTTTTTTGTTCCAATAATTAGAGATAACCCTCAAGATTCAGG
CTCCTTAGGAGCGGGGATAA

Product: integrase-recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MREKTLRSEVLEEFATYLELEGKSKNTIRMYTYFLSKFLEEGYSPTARDALRFLAKLRAKGYSIRSINLVVQALKAYFKF
EGLNEEAERLRNPKIPKTLPKSLTEEEVKKLIEVIPKDKIRDRLIVLLLYGTGLRVSELCNLKIEDINFEKGFLTVRGGK
GGKDRTIPIPQPLLTEIKNYLRRRTDDSPYLFVESRRKNKEKLSPKTVWRILKEYGRKAGIKVTPHQLRHSFATHMLERG
IDIRIIQELLGHASLSTTQIYTRVTAKHLKEAVERANLLENLIGGE

Sequences:

>Translated_286_residues
MREKTLRSEVLEEFATYLELEGKSKNTIRMYTYFLSKFLEEGYSPTARDALRFLAKLRAKGYSIRSINLVVQALKAYFKF
EGLNEEAERLRNPKIPKTLPKSLTEEEVKKLIEVIPKDKIRDRLIVLLLYGTGLRVSELCNLKIEDINFEKGFLTVRGGK
GGKDRTIPIPQPLLTEIKNYLRRRTDDSPYLFVESRRKNKEKLSPKTVWRILKEYGRKAGIKVTPHQLRHSFATHMLERG
IDIRIIQELLGHASLSTTQIYTRVTAKHLKEAVERANLLENLIGGE
>Mature_286_residues
MREKTLRSEVLEEFATYLELEGKSKNTIRMYTYFLSKFLEEGYSPTARDALRFLAKLRAKGYSIRSINLVVQALKAYFKF
EGLNEEAERLRNPKIPKTLPKSLTEEEVKKLIEVIPKDKIRDRLIVLLLYGTGLRVSELCNLKIEDINFEKGFLTVRGGK
GGKDRTIPIPQPLLTEIKNYLRRRTDDSPYLFVESRRKNKEKLSPKTVWRILKEYGRKAGIKVTPHQLRHSFATHMLERG
IDIRIIQELLGHASLSTTQIYTRVTAKHLKEAVERANLLENLIGGE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=239, Percent_Identity=37.2384937238494, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789261, Length=286, Percent_Identity=33.9160839160839, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1790768, Length=188, Percent_Identity=30.3191489361702, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=31.3186813186813, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_PYRFU (Q8TZV9)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579597.1
- ProteinModelPortal:   Q8TZV9
- SMR:   Q8TZV9
- EnsemblBacteria:   EBPYRT00000005927
- GeneID:   1469747
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1868
- NMPDR:   fig|186497.1.peg.1917
- GeneTree:   EBGT00050000023395
- HOGENOM:   HBG727654
- OMA:   NEEDINW
- ProtClustDB:   CLSK340523
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 33130; Mature: 33130

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: ACT_SITE 135-135 ACT_SITE 160-160 ACT_SITE 226-226 ACT_SITE 229-229 ACT_SITE 252-252 ACT_SITE 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKTLRSEVLEEFATYLELEGKSKNTIRMYTYFLSKFLEEGYSPTARDALRFLAKLRAK
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GYSIRSINLVVQALKAYFKFEGLNEEAERLRNPKIPKTLPKSLTEEEVKKLIEVIPKDKI
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCHHH
RDRLIVLLLYGTGLRVSELCNLKIEDINFEKGFLTVRGGKGGKDRTIPIPQPLLTEIKNY
HHHHEEHHHCCCCCCHHHHHCCEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
LRRRTDDSPYLFVESRRKNKEKLSPKTVWRILKEYGRKAGIKVTPHQLRHSFATHMLERG
HHHCCCCCCEEEEECHHCCHHHCCHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHCC
IDIRIIQELLGHASLSTTQIYTRVTAKHLKEAVERANLLENLIGGE
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MREKTLRSEVLEEFATYLELEGKSKNTIRMYTYFLSKFLEEGYSPTARDALRFLAKLRAK
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GYSIRSINLVVQALKAYFKFEGLNEEAERLRNPKIPKTLPKSLTEEEVKKLIEVIPKDKI
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCHHH
RDRLIVLLLYGTGLRVSELCNLKIEDINFEKGFLTVRGGKGGKDRTIPIPQPLLTEIKNY
HHHHEEHHHCCCCCCHHHHHCCEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
LRRRTDDSPYLFVESRRKNKEKLSPKTVWRILKEYGRKAGIKVTPHQLRHSFATHMLERG
HHHCCCCCCEEEEECHHCCHHHCCHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHCC
IDIRIIQELLGHASLSTTQIYTRVTAKHLKEAVERANLLENLIGGE
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA