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The map label for this gene is trkG [C]

Identifier: 18978228

GI number: 18978228

Start: 1713098

End: 1714615

Strand: Direct

Name: trkG [C]

Synonym: PF1856

Alternate gene names: 18978228

Gene position: 1713098-1714615 (Clockwise)

Preceding gene: 18978227

Following gene: 18978229

Centisome position: 89.77

GC content: 38.8

Gene sequence:

>1518_bases
ATGTTTTTATTTTTAACATGCAAAATAGGCAACCGTATGGTCAAATTAAGGACATTTATAAACATCTCAGAAGATCTCTT
CGTAATCAGAAACTTAATTGGAGCAATTTTGCAGGGTATTGGATTAGCTTATTTAGTTCCAGTTTTGCTTGCCTGGTTTT
ATCCAGAAGAGATACCCTTGGTAATCTACTTCGCAATTCCTGGGTTTTCCTGTATTATTTTGGGGTGGGTGTTATCTAAA
CACATGGAAAAGATCGAAGACGTAAATCTAAGACAGGCAATGATGGCGTCGGCATTTATTTGGCTTTTCGCTTCCTTAGT
TAGTGTTATTCCCTTTATGGGAATAGCAAAGATGAGATTTGTAGATTCATACTTCGAAACAATGAGCGCATGGACAGGGA
CTGGACTAACAATGATGAGCAACCTAGAGAGCTATCCAAAAATTCTCCTCTTTTGGAGAGCTTGGATGCAATGGCTTGGT
GGGATAGGAATAGTTTTGGTTGCACTAACAGTTCTCATAAGACCTGGTGTAGCTGCAGCTAGGCTATATAAGGCTGAGGC
CAGGAGCGAGAGAATATTGCCTAACTTTGTAAACACGGCAAAAATTATAGTTCAGATTTATGCAGTCCTAACGCTCCTAG
GCATTTACTTGTACTATAGCAATGGGATGAGTTTGTTTGATGCAACAATTCACTCAATGACTGGCCTGGGAACTGGTGGT
ATGAGTAGTCATGACTTGAGCATTGGATACTTTAATTCTCTTGCAATAGAAACAGTTACTGTATTCCTCATGATAATGGG
TGCCACAAACTTTACTGTCCATTATAGGATGTTCAAAAATCGTTCTCTCAAAGAATTCTTCAGAGATATTCAAGTTAGGT
ATATGCTTTACTTTATTACTTTAATAGTGGCTCTAATGACATACTCTCTGGTCTTTTTTGGACATTTAACTCCAATAAGG
GCACTAAGAGAATCAATATTTCATGCAGTTTCAGCAATTACATGTACTGGATTTGGAATAAGCAATTTGGCCGAATATCC
AGAGATAGATAAGATACTCCTGGCAATATTAATGGTCATAGGAGGAAGTGCAGGTAGTACTTCTGGTGGTATAAAGTTGA
TTAGAATAGTTCTCATGTACCAAAGCCTTAAGTGGACCATAGAACAGGCAATTCTTCCCAAGGGGGCGGTAATAAGAAAG
AGAGTCAATGGATATGAGTTCACAGAAGAGGAAATTCAAGAAGTTTTAGGCTTTACAATGACGTACATAGCATTTCTCCT
CCTGGGAACTTTATATATTATGCTAAGGCTAGGAGTTAGATTTGCAGATGCACTATTTGAAGTAGCCTCCGCAATTGGAA
ACGTAGGGCTTAGCGTCGGAATAACGTCTCCACTGCTTCCCCTAGACATAAAAATTCTTCTCACAATATTAATGTGGGTG
GGAAGGCTTGAAATATTCTCGACGATAGTCTTTATAGTTGGACTAGCAATGATTTTCTCCAGGAGGTCCAAAGAGTGA

Upstream 100 bases:

>100_bases
GAAGATTTATGAAGTTCCTCCAGATGCTCGGAAACATATTTCTCGCCCCTTAGTTCTCCCAGGAGGGGAAGATAAGATAT
TAGAGGCTCTATAAAAAGAA

Downstream 100 bases:

>100_bases
AGATAATTGAAGTTAGGGATGTTAGCTTCAAATATTTTGGAGCTAAACAATACTCCTAAGGGATGTTAATTTAACTGTTA
GAAAGGGGGAATTTTTAGGA

Product: trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MFLFLTCKIGNRMVKLRTFINISEDLFVIRNLIGAILQGIGLAYLVPVLLAWFYPEEIPLVIYFAIPGFSCIILGWVLSK
HMEKIEDVNLRQAMMASAFIWLFASLVSVIPFMGIAKMRFVDSYFETMSAWTGTGLTMMSNLESYPKILLFWRAWMQWLG
GIGIVLVALTVLIRPGVAAARLYKAEARSERILPNFVNTAKIIVQIYAVLTLLGIYLYYSNGMSLFDATIHSMTGLGTGG
MSSHDLSIGYFNSLAIETVTVFLMIMGATNFTVHYRMFKNRSLKEFFRDIQVRYMLYFITLIVALMTYSLVFFGHLTPIR
ALRESIFHAVSAITCTGFGISNLAEYPEIDKILLAILMVIGGSAGSTSGGIKLIRIVLMYQSLKWTIEQAILPKGAVIRK
RVNGYEFTEEEIQEVLGFTMTYIAFLLLGTLYIMLRLGVRFADALFEVASAIGNVGLSVGITSPLLPLDIKILLTILMWV
GRLEIFSTIVFIVGLAMIFSRRSKE

Sequences:

>Translated_505_residues
MFLFLTCKIGNRMVKLRTFINISEDLFVIRNLIGAILQGIGLAYLVPVLLAWFYPEEIPLVIYFAIPGFSCIILGWVLSK
HMEKIEDVNLRQAMMASAFIWLFASLVSVIPFMGIAKMRFVDSYFETMSAWTGTGLTMMSNLESYPKILLFWRAWMQWLG
GIGIVLVALTVLIRPGVAAARLYKAEARSERILPNFVNTAKIIVQIYAVLTLLGIYLYYSNGMSLFDATIHSMTGLGTGG
MSSHDLSIGYFNSLAIETVTVFLMIMGATNFTVHYRMFKNRSLKEFFRDIQVRYMLYFITLIVALMTYSLVFFGHLTPIR
ALRESIFHAVSAITCTGFGISNLAEYPEIDKILLAILMVIGGSAGSTSGGIKLIRIVLMYQSLKWTIEQAILPKGAVIRK
RVNGYEFTEEEIQEVLGFTMTYIAFLLLGTLYIMLRLGVRFADALFEVASAIGNVGLSVGITSPLLPLDIKILLTILMWV
GRLEIFSTIVFIVGLAMIFSRRSKE
>Mature_505_residues
MFLFLTCKIGNRMVKLRTFINISEDLFVIRNLIGAILQGIGLAYLVPVLLAWFYPEEIPLVIYFAIPGFSCIILGWVLSK
HMEKIEDVNLRQAMMASAFIWLFASLVSVIPFMGIAKMRFVDSYFETMSAWTGTGLTMMSNLESYPKILLFWRAWMQWLG
GIGIVLVALTVLIRPGVAAARLYKAEARSERILPNFVNTAKIIVQIYAVLTLLGIYLYYSNGMSLFDATIHSMTGLGTGG
MSSHDLSIGYFNSLAIETVTVFLMIMGATNFTVHYRMFKNRSLKEFFRDIQVRYMLYFITLIVALMTYSLVFFGHLTPIR
ALRESIFHAVSAITCTGFGISNLAEYPEIDKILLAILMVIGGSAGSTSGGIKLIRIVLMYQSLKWTIEQAILPKGAVIRK
RVNGYEFTEEEIQEVLGFTMTYIAFLLLGTLYIMLRLGVRFADALFEVASAIGNVGLSVGITSPLLPLDIKILLTILMWV
GRLEIFSTIVFIVGLAMIFSRRSKE

Specific function: Low-Affinity Potassium Transport System. Interacts With Trk System Potassium Uptake Protein Trka. Trke Increases The Affinity Of The System. [C]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=476, Percent_Identity=28.5714285714286, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI48994987, Length=415, Percent_Identity=29.6385542168675, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 56668; Mature: 56668

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]