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The map label for this gene is thiP [H]

Identifier: 18978120

GI number: 18978120

Start: 1625662

End: 1626630

Strand: Direct

Name: thiP [H]

Synonym: PF1748

Alternate gene names: 18978120

Gene position: 1625662-1626630 (Clockwise)

Preceding gene: 18978119

Following gene: 18978121

Centisome position: 85.19

GC content: 42.21

Gene sequence:

>969_bases
ATGAGAATGAAGTGGAGAAACTTCATAGTTTTCCTACCTCTTGTTTTCCTCTTCATGTTCTTTTATTTCCCTCTAATGAG
CATATTAAAGGAGGGTTTGTGGGATAACGGGATTACGCTGAAGTATATTCTCCAGGTAATCTCAAACAGCTATCACAGAA
GGGTTGTATTTTTCACTTTTTGGCAGGCACTTGCCTCTACACTCTTAACACTGTTGTTGGGGTTACCTGGGGCGTATATC
TTTGCAAAATATGACTTCCCAGGCAAGGGAATTTTAAAAGCCCTTCTAACGGTTCCCTTTGTAATGCCTAGCATCATGGT
TGCCTTGGGCTTTATACTCCTATTTGGGCGATCTGGAGTAATTGCACAGCTGATTGGAAGGGATCCAGGAATTCTCTACT
CATGGAAGGCAATAATTTTGGCTCACGCCTTTTACAACTTTCCCGTGGTTGTGAGGATGGTGTCTTCATTATGGCAGCGC
ATAAACCCCCACTACGAAGAAGCCGCCATAAGCTTGGGGGCAAGGGGATTCACACTCTTTAGGAAAGTCACCTTACCGAT
GCTCATGCCGGCTATATTTGCCTCCTCAATGCTGACATTTGTCTTCTGCTTTTTGAGTTTTTCAATCCCTTTAATCCTTG
GTGGATACCAGTATGCGACCATAGAGGTTGACATATTCACGGCAATAATGACCCTCTTGGACTTCAAAACAGGAGCGGCT
TTGGCTATAATTCAAATCTTTTTAAGCTTTATTTTTATGTACCTCTACTTAAAAAGCCTTGACCTTTATGCAAAGGCCGA
GGAACAGAGAATATTTAGAAAACCACTACCTCTAACCTTGAAAGAACTTTTGGGCGTAAAGGGAGTGTTTATAACACTCT
ACTCCAGCGTAGTGTTCCTTTTTATTTTATCTCCTCTAATAGCTGTTGTTTACCACTCGTTCACCTATGGAGGCAGGTTT
ACCCCTTGA

Upstream 100 bases:

>100_bases
ACGAGAACAAGATTTTGCTGTATTACGGTGGAGCTGATAGGCATATTGGTTTAGCCTACTGGACAACAGACTTATAAAAC
CATATAACTCATTAAATCCG

Downstream 100 bases:

>100_bases
ATGGTACAGAAGGGTTTTCTCCCCAGAGTATAACCCTATATTCGGTGCAAACAGCATAACAGCGATTAGGAATTCCTTCT
TCTTTGGATTTTCTACAGTT

Product: putative sulfate transport system permease protein, ABC transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRMKWRNFIVFLPLVFLFMFFYFPLMSILKEGLWDNGITLKYILQVISNSYHRRVVFFTFWQALASTLLTLLLGLPGAYI
FAKYDFPGKGILKALLTVPFVMPSIMVALGFILLFGRSGVIAQLIGRDPGILYSWKAIILAHAFYNFPVVVRMVSSLWQR
INPHYEEAAISLGARGFTLFRKVTLPMLMPAIFASSMLTFVFCFLSFSIPLILGGYQYATIEVDIFTAIMTLLDFKTGAA
LAIIQIFLSFIFMYLYLKSLDLYAKAEEQRIFRKPLPLTLKELLGVKGVFITLYSSVVFLFILSPLIAVVYHSFTYGGRF
TP

Sequences:

>Translated_322_residues
MRMKWRNFIVFLPLVFLFMFFYFPLMSILKEGLWDNGITLKYILQVISNSYHRRVVFFTFWQALASTLLTLLLGLPGAYI
FAKYDFPGKGILKALLTVPFVMPSIMVALGFILLFGRSGVIAQLIGRDPGILYSWKAIILAHAFYNFPVVVRMVSSLWQR
INPHYEEAAISLGARGFTLFRKVTLPMLMPAIFASSMLTFVFCFLSFSIPLILGGYQYATIEVDIFTAIMTLLDFKTGAA
LAIIQIFLSFIFMYLYLKSLDLYAKAEEQRIFRKPLPLTLKELLGVKGVFITLYSSVVFLFILSPLIAVVYHSFTYGGRF
TP
>Mature_322_residues
MRMKWRNFIVFLPLVFLFMFFYFPLMSILKEGLWDNGITLKYILQVISNSYHRRVVFFTFWQALASTLLTLLLGLPGAYI
FAKYDFPGKGILKALLTVPFVMPSIMVALGFILLFGRSGVIAQLIGRDPGILYSWKAIILAHAFYNFPVVVRMVSSLWQR
INPHYEEAAISLGARGFTLFRKVTLPMLMPAIFASSMLTFVFCFLSFSIPLILGGYQYATIEVDIFTAIMTLLDFKTGAA
LAIIQIFLSFIFMYLYLKSLDLYAKAEEQRIFRKPLPLTLKELLGVKGVFITLYSSVVFLFILSPLIAVVYHSFTYGGRF
TP

Specific function: Part of the ABC transporter complex thiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=203, Percent_Identity=32.0197044334975, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786254, Length=219, Percent_Identity=31.9634703196347, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082099, Length=238, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786980, Length=226, Percent_Identity=28.7610619469027, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005947 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36747; Mature: 36747

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMKWRNFIVFLPLVFLFMFFYFPLMSILKEGLWDNGITLKYILQVISNSYHRRVVFFTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
WQALASTLLTLLLGLPGAYIFAKYDFPGKGILKALLTVPFVMPSIMVALGFILLFGRSGV
HHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IAQLIGRDPGILYSWKAIILAHAFYNFPVVVRMVSSLWQRINPHYEEAAISLGARGFTLF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
RKVTLPMLMPAIFASSMLTFVFCFLSFSIPLILGGYQYATIEVDIFTAIMTLLDFKTGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCHH
LAIIQIFLSFIFMYLYLKSLDLYAKAEEQRIFRKPLPLTLKELLGVKGVFITLYSSVVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHH
FILSPLIAVVYHSFTYGGRFTP
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRMKWRNFIVFLPLVFLFMFFYFPLMSILKEGLWDNGITLKYILQVISNSYHRRVVFFTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
WQALASTLLTLLLGLPGAYIFAKYDFPGKGILKALLTVPFVMPSIMVALGFILLFGRSGV
HHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IAQLIGRDPGILYSWKAIILAHAFYNFPVVVRMVSSLWQRINPHYEEAAISLGARGFTLF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
RKVTLPMLMPAIFASSMLTFVFCFLSFSIPLILGGYQYATIEVDIFTAIMTLLDFKTGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCHH
LAIIQIFLSFIFMYLYLKSLDLYAKAEEQRIFRKPLPLTLKELLGVKGVFITLYSSVVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHH
FILSPLIAVVYHSFTYGGRFTP
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA