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The map label for this gene is mpg1 [H]

Identifier: 18978100

GI number: 18978100

Start: 1605924

End: 1607009

Strand: Direct

Name: mpg1 [H]

Synonym: PF1728

Alternate gene names: 18978100

Gene position: 1605924-1607009 (Clockwise)

Preceding gene: 18978097

Following gene: 33359571

Centisome position: 84.16

GC content: 37.57

Gene sequence:

>1086_bases
ATGCAGGCAGTAGTTCTAGCAGGAGGTAAAGGAACCCGCCTATTGCCACTGACAGTATATCGACCAAAACCAATGATACC
ATTTTTCAACAGGCCAATAATGGAATACATTGTAGAAAGCTTGGTTAAATTTGGAGTAGATGAAATCATTGTCCTAGTAG
GGTATCTGAAAGAGAGAATTTTTGAATACTTTGGAAATGGAGAAGAATTTGGAGTAGAAATAAAGTACTCAAATGGGGAA
AATCTAAAACTTGGAACTGCGGGAGCTCTAAAAAAAGCTGAAAAACTTATCCAAGACACCTTCTTAGTAGTTTCGGGAGA
TATTCTAACAAATTTGGACTTTAGGAGTTTAGTTGAATACCACAAAAAGAAGGGAGGCCCCGCGACAATAGCCCTAACAA
AAGTGGAAGATCCCAGTGCGTATGGAGTAGCGGTATTAGATAAGGAAGGGAGAATATCATACTTCAAAGAGAAACCAAAA
AGGGAAGAGGCTCCAAGCAATTTGGTAAATGCAGGAATATATGTATTTGAACCAGAAATTTTTGATTTAATCCCGAAGGG
TAAAAACTTCGATTTTTCCTTGGATCTCTTTCCAAAAATGCTAAATGAAAACATTCCTATCTACGGATATCCTTTTGATG
AGTACTGGAATGATATAGGAAGACCCTCCACATATCTCCAAGCTACTGAAGATGTATTTTTGGGTAAACTAAGGCTACCT
CAAATAAATGTTGGATCACTAAAAGGAAACATTGAAAAAGGGGGAAGTCTATTCACGGGAAGTAGGTGCATACTAAGAAG
ACCAAGAATCATCGGCTTTGCAGTCTTGGGGAACAATGTTGAAATCAGCAAAGATGTAACAATAGAAAGGTCAGTTATAT
TCTCCAACGTTACCATAGAAGAAGGAGCAGAAATTAGAGAGGCAATAATTGGAGAAAACGTCTACATAGGTAAGGGAGTT
GTTATTGAGCCAGGAAGTGTTATTGGAGATAACTCAATAATTGAAGACTTTAGTAAAGTTGGTGCAAATGTTAAGATTTG
GGCAGATTCGAGAATTGGTAAAGAAAGTATAATACTACCCGACTGA

Upstream 100 bases:

>100_bases
CACTTCTTAATCTTCATTCTTTCCCCCCATTATCATTTTACTAAACCACAACATATAAAACTTCTCTTTAACTAACTAAA
AAAGTGGAGAGGGAGGTAAA

Downstream 100 bases:

>100_bases
GGTGATGGAAATGGAGTTATATTACTCAGAAAAGTTCAATCCAGAAGAACTTGCCCTCCTGGGAAGAGCTATAGGAACTG
CTACCCAGGGGACAATTGTA

Product: NDP-sugar synthase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQAVVLAGGKGTRLLPLTVYRPKPMIPFFNRPIMEYIVESLVKFGVDEIIVLVGYLKERIFEYFGNGEEFGVEIKYSNGE
NLKLGTAGALKKAEKLIQDTFLVVSGDILTNLDFRSLVEYHKKKGGPATIALTKVEDPSAYGVAVLDKEGRISYFKEKPK
REEAPSNLVNAGIYVFEPEIFDLIPKGKNFDFSLDLFPKMLNENIPIYGYPFDEYWNDIGRPSTYLQATEDVFLGKLRLP
QINVGSLKGNIEKGGSLFTGSRCILRRPRIIGFAVLGNNVEISKDVTIERSVIFSNVTIEEGAEIREAIIGENVYIGKGV
VIEPGSVIGDNSIIEDFSKVGANVKIWADSRIGKESIILPD

Sequences:

>Translated_361_residues
MQAVVLAGGKGTRLLPLTVYRPKPMIPFFNRPIMEYIVESLVKFGVDEIIVLVGYLKERIFEYFGNGEEFGVEIKYSNGE
NLKLGTAGALKKAEKLIQDTFLVVSGDILTNLDFRSLVEYHKKKGGPATIALTKVEDPSAYGVAVLDKEGRISYFKEKPK
REEAPSNLVNAGIYVFEPEIFDLIPKGKNFDFSLDLFPKMLNENIPIYGYPFDEYWNDIGRPSTYLQATEDVFLGKLRLP
QINVGSLKGNIEKGGSLFTGSRCILRRPRIIGFAVLGNNVEISKDVTIERSVIFSNVTIEEGAEIREAIIGENVYIGKGV
VIEPGSVIGDNSIIEDFSKVGANVKIWADSRIGKESIILPD
>Mature_361_residues
MQAVVLAGGKGTRLLPLTVYRPKPMIPFFNRPIMEYIVESLVKFGVDEIIVLVGYLKERIFEYFGNGEEFGVEIKYSNGE
NLKLGTAGALKKAEKLIQDTFLVVSGDILTNLDFRSLVEYHKKKGGPATIALTKVEDPSAYGVAVLDKEGRISYFKEKPK
REEAPSNLVNAGIYVFEPEIFDLIPKGKNFDFSLDLFPKMLNENIPIYGYPFDEYWNDIGRPSTYLQATEDVFLGKLRLP
QINVGSLKGNIEKGGSLFTGSRCILRRPRIIGFAVLGNNVEISKDVTIERSVIFSNVTIEEGAEIREAIIGENVYIGKGV
VIEPGSVIGDNSIIEDFSKVGANVKIWADSRIGKESIILPD

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=346, Percent_Identity=33.2369942196532, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI11761619, Length=335, Percent_Identity=33.134328358209, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI31881779, Length=415, Percent_Identity=23.855421686747, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI45447090, Length=415, Percent_Identity=23.855421686747, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1789837, Length=384, Percent_Identity=25.5208333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788351, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790224, Length=185, Percent_Identity=27.5675675675676, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=350, Percent_Identity=34.2857142857143, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17509979, Length=342, Percent_Identity=26.6081871345029, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17509981, Length=332, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=342, Percent_Identity=35.9649122807018, Blast_Score=185, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320417, Length=409, Percent_Identity=28.361858190709, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21355443, Length=343, Percent_Identity=34.1107871720117, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24644084, Length=343, Percent_Identity=34.1107871720117, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24653912, Length=386, Percent_Identity=25.1295336787565, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 40085; Mature: 40085

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVVLAGGKGTRLLPLTVYRPKPMIPFFNRPIMEYIVESLVKFGVDEIIVLVGYLKERI
CCEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FEYFGNGEEFGVEIKYSNGENLKLGTAGALKKAEKLIQDTFLVVSGDILTNLDFRSLVEY
HHHHCCCCEEEEEEEECCCCEEEECCHHHHHHHHHHHHHEEEEEECHHHCCCCHHHHHHH
HKKKGGPATIALTKVEDPSAYGVAVLDKEGRISYFKEKPKREEAPSNLVNAGIYVFEPEI
HHHCCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHCCCCCCCCCCHHHHCCEEEECCHH
FDLIPKGKNFDFSLDLFPKMLNENIPIYGYPFDEYWNDIGRPSTYLQATEDVFLGKLRLP
HHHCCCCCCCEEEHHHHHHHHCCCCCEEECCHHHHHHHHCCCCHHHEEHHHHHCCEEECC
QINVGSLKGNIEKGGSLFTGSRCILRRPRIIGFAVLGNNVEISKDVTIERSVIFSNVTIE
CEECCCCCCCCCCCCCEEECCHHEEECCCEEEEEEECCCEEECCCCEEEEEEEEEECCHH
EGAEIREAIIGENVYIGKGVVIEPGSVIGDNSIIEDFSKVGANVKIWADSRIGKESIILP
CCHHHHHHHHCCCEEECCCEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
D
C
>Mature Secondary Structure
MQAVVLAGGKGTRLLPLTVYRPKPMIPFFNRPIMEYIVESLVKFGVDEIIVLVGYLKERI
CCEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FEYFGNGEEFGVEIKYSNGENLKLGTAGALKKAEKLIQDTFLVVSGDILTNLDFRSLVEY
HHHHCCCCEEEEEEEECCCCEEEECCHHHHHHHHHHHHHEEEEEECHHHCCCCHHHHHHH
HKKKGGPATIALTKVEDPSAYGVAVLDKEGRISYFKEKPKREEAPSNLVNAGIYVFEPEI
HHHCCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHCCCCCCCCCCHHHHCCEEEECCHH
FDLIPKGKNFDFSLDLFPKMLNENIPIYGYPFDEYWNDIGRPSTYLQATEDVFLGKLRLP
HHHCCCCCCCEEEHHHHHHHHCCCCCEEECCHHHHHHHHCCCCHHHEEHHHHHCCEEECC
QINVGSLKGNIEKGGSLFTGSRCILRRPRIIGFAVLGNNVEISKDVTIERSVIFSNVTIE
CEECCCCCCCCCCCCCEEECCHHEEECCCEEEEEEECCCEEECCCCEEEEEEEEEECCHH
EGAEIREAIIGENVYIGKGVVIEPGSVIGDNSIIEDFSKVGANVKIWADSRIGKESIILP
CCHHHHHHHHCCCEEECCCEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]