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The map label for this gene is 18978090

Identifier: 18978090

GI number: 18978090

Start: 1597514

End: 1598530

Strand: Reverse

Name: 18978090

Synonym: PF1718

Alternate gene names: NA

Gene position: 1598530-1597514 (Counterclockwise)

Preceding gene: 18978098

Following gene: 18978089

Centisome position: 83.77

GC content: 42.77

Gene sequence:

>1017_bases
ATGGATATAAAGCCTGGAAAAATTACTGTTCAAGCTAATCCAAACATGCCTGAAGAGATAGCTAATTTGTTTAGAAAACA
ACACTATGAACTCGTAGGTAGGCACAGCGGGGTTAAACTTTGCCACTGGTTGAAGAAGAGTCTAACGGAAGGGAGATTCT
GTTATAAGCAGAAGTTCTATGGCATTCACTCTCACCGTTGCCTTCAAATGACTCCAGTGCTAGCGTGGTGCACCCACAAC
TGTATCTTCTGCTGGCGTCCAATGGAGACTTTCTTAGGTACTGAAGTTCCAGAGCCCTGGGATGACCCAGCTTTCATAGT
TGAGGAGAGTATAAAGGCCCAAAGAAAGCTGTTGGTGGGGTACAAGGGTAATCCAAAAGTTGACAAGAAAAAATTTGAGG
AAGCTTGGGAACCAAAGCATGCTGCAATAAGTCTTTCAGGGGAGCCAATGCTTTATCCATATATGGGAGATCTGGTAGAG
GAGTTCCACAAGAGAGGGTTCACGACATTTATAGTTACCAACGGAACAGTCCCAGAAAGCCTCAGGGAGATGATAAAGGA
TGATAAGCTACCAACTCAGCTCTATGTATCTCTGACAGCTCCGGATATAGAATCCTATAACAAAGTAAATATTCCTATGA
TCCCAGATGGGTGGGAGAAGATACTGGAGTTCCTAGAATTGATGAGAGATATCCCAACGAGAACTGTTGTTAGACTAACA
CTAGTTAAGGGAGAGAACATGCACAATCCAGAAGGATACGCTAGGCTAATAATGAAAGCGAGGCCAATGTTCGTTGAGGC
AAAGGCTTACATGTTTGTAGGATTTTCAAGGAATAGGCTCACAATAAACAACATGCCAAGCCATGAAGACATAAGAGAAT
TCGCTGAAGCACTGGTCAAGTATCTTCCGGGTTATCACATTGAAGATGAATATGAACCAAGTAGGGTAGTTTTGATTATG
AGAGACGATGTAGATCCTTCTGGAACAGGACTGGAGGGGAGGTTTATTAAACATTGA

Upstream 100 bases:

>100_bases
TAGTTTTCAAAAAATGTTGTTGGTTAAATGAAGGTAAATAACTTTTTAAATGATTATTCTGGTATTTAAGTTAGGCGAGC
TAATCTGGAGGTGAGTGAGA

Downstream 100 bases:

>100_bases
ATTCCCAGGAATAAAGCTATAAATGGAATAGCTATCTACCATTTTGGGGGAGAGGACAATGGGTGAGAAAAGAAAAACTA
GGCAGGCGGAGGTAAATATA

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDIKPGKITVQANPNMPEEIANLFRKQHYELVGRHSGVKLCHWLKKSLTEGRFCYKQKFYGIHSHRCLQMTPVLAWCTHN
CIFCWRPMETFLGTEVPEPWDDPAFIVEESIKAQRKLLVGYKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVE
EFHKRGFTTFIVTNGTVPESLREMIKDDKLPTQLYVSLTAPDIESYNKVNIPMIPDGWEKILEFLELMRDIPTRTVVRLT
LVKGENMHNPEGYARLIMKARPMFVEAKAYMFVGFSRNRLTINNMPSHEDIREFAEALVKYLPGYHIEDEYEPSRVVLIM
RDDVDPSGTGLEGRFIKH

Sequences:

>Translated_338_residues
MDIKPGKITVQANPNMPEEIANLFRKQHYELVGRHSGVKLCHWLKKSLTEGRFCYKQKFYGIHSHRCLQMTPVLAWCTHN
CIFCWRPMETFLGTEVPEPWDDPAFIVEESIKAQRKLLVGYKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVE
EFHKRGFTTFIVTNGTVPESLREMIKDDKLPTQLYVSLTAPDIESYNKVNIPMIPDGWEKILEFLELMRDIPTRTVVRLT
LVKGENMHNPEGYARLIMKARPMFVEAKAYMFVGFSRNRLTINNMPSHEDIREFAEALVKYLPGYHIEDEYEPSRVVLIM
RDDVDPSGTGLEGRFIKH
>Mature_338_residues
MDIKPGKITVQANPNMPEEIANLFRKQHYELVGRHSGVKLCHWLKKSLTEGRFCYKQKFYGIHSHRCLQMTPVLAWCTHN
CIFCWRPMETFLGTEVPEPWDDPAFIVEESIKAQRKLLVGYKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVE
EFHKRGFTTFIVTNGTVPESLREMIKDDKLPTQLYVSLTAPDIESYNKVNIPMIPDGWEKILEFLELMRDIPTRTVVRLT
LVKGENMHNPEGYARLIMKARPMFVEAKAYMFVGFSRNRLTINNMPSHEDIREFAEALVKYLPGYHIEDEYEPSRVVLIM
RDDVDPSGTGLEGRFIKH

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=295, Percent_Identity=39.6610169491525, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI224282123, Length=257, Percent_Identity=36.1867704280156, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI224282125, Length=267, Percent_Identity=35.5805243445693, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6325049, Length=308, Percent_Identity=38.6363636363636, Blast_Score=219, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 39240; Mature: 39240

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKPGKITVQANPNMPEEIANLFRKQHYELVGRHSGVKLCHWLKKSLTEGRFCYKQKFY
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHC
GIHSHRCLQMTPVLAWCTHNCIFCWRPMETFLGTEVPEPWDDPAFIVEESIKAQRKLLVG
CCCCCCHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEE
YKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTVPES
ECCCCCCCHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEEEEEECCCCHHH
LREMIKDDKLPTQLYVSLTAPDIESYNKVNIPMIPDGWEKILEFLELMRDIPTRTVVRLT
HHHHHHCCCCCEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
LVKGENMHNPEGYARLIMKARPMFVEAKAYMFVGFSRNRLTINNMPSHEDIREFAEALVK
EEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHH
YLPGYHIEDEYEPSRVVLIMRDDVDPSGTGLEGRFIKH
HCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEECC
>Mature Secondary Structure
MDIKPGKITVQANPNMPEEIANLFRKQHYELVGRHSGVKLCHWLKKSLTEGRFCYKQKFY
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHC
GIHSHRCLQMTPVLAWCTHNCIFCWRPMETFLGTEVPEPWDDPAFIVEESIKAQRKLLVG
CCCCCCHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEE
YKGNPKVDKKKFEEAWEPKHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTVPES
ECCCCCCCHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEEEEEECCCCHHH
LREMIKDDKLPTQLYVSLTAPDIESYNKVNIPMIPDGWEKILEFLELMRDIPTRTVVRLT
HHHHHHCCCCCEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
LVKGENMHNPEGYARLIMKARPMFVEAKAYMFVGFSRNRLTINNMPSHEDIREFAEALVK
EEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHH
YLPGYHIEDEYEPSRVVLIMRDDVDPSGTGLEGRFIKH
HCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]