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The map label for this gene is aroA [H]

Identifier: 18978071

GI number: 18978071

Start: 1579245

End: 1580567

Strand: Direct

Name: aroA [H]

Synonym: PF1699

Alternate gene names: 18978071

Gene position: 1579245-1580567 (Clockwise)

Preceding gene: 18978070

Following gene: 18978072

Centisome position: 82.76

GC content: 40.67

Gene sequence:

>1323_bases
TTGGGAAACCTTATATCAAGGAGTAACTTTCTTTCCCTTTTTAAATTCTGGCCAGCTCCACTAATCCAAAAAACAATAAA
TTCATTGGAAGTAGCATTCCACATGCTTAGAATTGTTCCACCAAAAGAAATTCAAGGTGAAGTAATAGCCCCGCCCTCAA
AGAGCTACACCCATAGGGGTTATTTTTTGTCCCTCCTTGCAGATGAAAAAAGTATAGTAGAGAGACCCCTAATTAGTGAT
GATACCCTTGCAACCATAGATGCAATTAGAGCTTTTGGTGCTGATCTCATAGAAGAGGTGGTCTATCCTCCCGAAGAATT
AAGGCCAAACTATATATTTGCCCGAGATTCTGGAACAACAGCAAGGATTTCAATAATAGTTTCTTCCCTAGCTAAGGGTG
TTAGTGTAATAGATGGTAGGGAACAGCTCCGTAGGAGACCAATGGAAGATGGAGTATCTTCTTTGAGAATGATTGGTGTA
GAAGCAATTGGAAAGAGACTTCCAGTGAAAGTCTTTGGGAGGGGAAGAATTAGTGCCAAAGAAGTCTCCATAGTGGCCGA
AAAGTCCTCTCAATTTGCAACAGGCTTTCTAATACTAGCAGCGAAGATCGGATTGAAAGTCGAAATAGTGAAACCAGTCT
CAAAGCCTTATATTGAGATGACACTAAAAACCATGGAAGAGTTTGGCGTTAAATACGATAAAGCTCAAGAAAATGAGAGA
CTAGTAATTTTTGTTGACCCAGGAGTTAAGGGGACAAAATTTAAGGTTCCAGGGGATTATTCCTCAGCGGCAAACTTCTT
AGTTGCCGGTGCACTCTACGGCAAGATAAGGGTCAGAAACTTGATGAGGGATGACGTTCAAGCAGACAAAGAAATCCTCA
ACATATTGAGGGAATATGGAGCAAAAGTTAAGGTAAAAGATGAGTATGTAGAAGTTGAAAGCAACGAAAGAAATCCATTA
AATGTAGATTGCTCAAACTTTCCTGATTTATTTCCCCTCCTAGCTGTTCTTGCGGCATATGCCGAAGGAAAAAGTGTGAT
ACGAGGGAGACAGTTGAGGATTAAAGAAAGTGACAGAATCCATGCAATGGCGGTAAATCTTTCAAGAGCTGGAATTAGAG
TTAGGGAGCTTAGTGATGGACTTGAAATCTGGGGTGGCCAACCTAAGGGATTTAGGGGGAAAACATTCAATGATCATAGG
ATTACAATGGCTTTAGCAATCCTCGCCCTGGGGGCTAAGGGCGAGAGTATAATTCCTGAAACTAAAAGTATTGCAAAGTC
CTATCCAAACTTTTTCGAGGATTTAATGAGGGTGATAAAATGA

Upstream 100 bases:

>100_bases
ATAATAACCGCAGAATCAAATCTCTTTAGGATAATCCCATATATAGGAACATTATTAGTGGTCACAATAATCATGAAAAA
AGTTAAAGCTCCCAGGGCTC

Downstream 100 bases:

>100_bases
ATGGGAAAATGTTGTCATTTCACTTATTTGGAGAGAGTCATGGGAAAGCCGTAGGAGAGTTCTAATAGAAGGAGTGCCTC
CTGGGATAAGAGTTAACCTG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MGNLISRSNFLSLFKFWPAPLIQKTINSLEVAFHMLRIVPPKEIQGEVIAPPSKSYTHRGYFLSLLADEKSIVERPLISD
DTLATIDAIRAFGADLIEEVVYPPEELRPNYIFARDSGTTARISIIVSSLAKGVSVIDGREQLRRRPMEDGVSSLRMIGV
EAIGKRLPVKVFGRGRISAKEVSIVAEKSSQFATGFLILAAKIGLKVEIVKPVSKPYIEMTLKTMEEFGVKYDKAQENER
LVIFVDPGVKGTKFKVPGDYSSAANFLVAGALYGKIRVRNLMRDDVQADKEILNILREYGAKVKVKDEYVEVESNERNPL
NVDCSNFPDLFPLLAVLAAYAEGKSVIRGRQLRIKESDRIHAMAVNLSRAGIRVRELSDGLEIWGGQPKGFRGKTFNDHR
ITMALAILALGAKGESIIPETKSIAKSYPNFFEDLMRVIK

Sequences:

>Translated_440_residues
MGNLISRSNFLSLFKFWPAPLIQKTINSLEVAFHMLRIVPPKEIQGEVIAPPSKSYTHRGYFLSLLADEKSIVERPLISD
DTLATIDAIRAFGADLIEEVVYPPEELRPNYIFARDSGTTARISIIVSSLAKGVSVIDGREQLRRRPMEDGVSSLRMIGV
EAIGKRLPVKVFGRGRISAKEVSIVAEKSSQFATGFLILAAKIGLKVEIVKPVSKPYIEMTLKTMEEFGVKYDKAQENER
LVIFVDPGVKGTKFKVPGDYSSAANFLVAGALYGKIRVRNLMRDDVQADKEILNILREYGAKVKVKDEYVEVESNERNPL
NVDCSNFPDLFPLLAVLAAYAEGKSVIRGRQLRIKESDRIHAMAVNLSRAGIRVRELSDGLEIWGGQPKGFRGKTFNDHR
ITMALAILALGAKGESIIPETKSIAKSYPNFFEDLMRVIK
>Mature_439_residues
GNLISRSNFLSLFKFWPAPLIQKTINSLEVAFHMLRIVPPKEIQGEVIAPPSKSYTHRGYFLSLLADEKSIVERPLISDD
TLATIDAIRAFGADLIEEVVYPPEELRPNYIFARDSGTTARISIIVSSLAKGVSVIDGREQLRRRPMEDGVSSLRMIGVE
AIGKRLPVKVFGRGRISAKEVSIVAEKSSQFATGFLILAAKIGLKVEIVKPVSKPYIEMTLKTMEEFGVKYDKAQENERL
VIFVDPGVKGTKFKVPGDYSSAANFLVAGALYGKIRVRNLMRDDVQADKEILNILREYGAKVKVKDEYVEVESNERNPLN
VDCSNFPDLFPLLAVLAAYAEGKSVIRGRQLRIKESDRIHAMAVNLSRAGIRVRELSDGLEIWGGQPKGFRGKTFNDHRI
TMALAILALGAKGESIIPETKSIAKSYPNFFEDLMRVIK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=432, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320332, Length=455, Percent_Identity=25.9340659340659, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 48972; Mature: 48840

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNLISRSNFLSLFKFWPAPLIQKTINSLEVAFHMLRIVPPKEIQGEVIAPPSKSYTHRG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCCC
YFLSLLADEKSIVERPLISDDTLATIDAIRAFGADLIEEVVYPPEELRPNYIFARDSGTT
EEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCC
ARISIIVSSLAKGVSVIDGREQLRRRPMEDGVSSLRMIGVEAIGKRLPVKVFGRGRISAK
HHHHHHHHHHHCCCHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
EVSIVAEKSSQFATGFLILAAKIGLKVEIVKPVSKPYIEMTLKTMEEFGVKYDKAQENER
HEEEEECCCCCHHHHHHHEEHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
LVIFVDPGVKGTKFKVPGDYSSAANFLVAGALYGKIRVRNLMRDDVQADKEILNILREYG
EEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKVKVKDEYVEVESNERNPLNVDCSNFPDLFPLLAVLAAYAEGKSVIRGRQLRIKESDRI
CEEEEEHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCEEEECCCCCE
HAMAVNLSRAGIRVRELSDGLEIWGGQPKGFRGKTFNDHRITMALAILALGAKGESIIPE
EEEEEEHHHCCEEEEEHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
TKSIAKSYPNFFEDLMRVIK
HHHHHHHCHHHHHHHHHHHC
>Mature Secondary Structure 
GNLISRSNFLSLFKFWPAPLIQKTINSLEVAFHMLRIVPPKEIQGEVIAPPSKSYTHRG
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCCC
YFLSLLADEKSIVERPLISDDTLATIDAIRAFGADLIEEVVYPPEELRPNYIFARDSGTT
EEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCC
ARISIIVSSLAKGVSVIDGREQLRRRPMEDGVSSLRMIGVEAIGKRLPVKVFGRGRISAK
HHHHHHHHHHHCCCHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
EVSIVAEKSSQFATGFLILAAKIGLKVEIVKPVSKPYIEMTLKTMEEFGVKYDKAQENER
HEEEEECCCCCHHHHHHHEEHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
LVIFVDPGVKGTKFKVPGDYSSAANFLVAGALYGKIRVRNLMRDDVQADKEILNILREYG
EEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKVKVKDEYVEVESNERNPLNVDCSNFPDLFPLLAVLAAYAEGKSVIRGRQLRIKESDRI
CEEEEEHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCEEEECCCCCE
HAMAVNLSRAGIRVRELSDGLEIWGGQPKGFRGKTFNDHRITMALAILALGAKGESIIPE
EEEEEEHHHCCEEEEEHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
TKSIAKSYPNFFEDLMRVIK
HHHHHHHCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA