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The map label for this gene is thrC [H]

Identifier: 18978011

GI number: 18978011

Start: 1530127

End: 1531164

Strand: Reverse

Name: thrC [H]

Synonym: PF1639

Alternate gene names: 18978011

Gene position: 1531164-1530127 (Counterclockwise)

Preceding gene: 18978012

Following gene: 18978010

Centisome position: 80.24

GC content: 39.6

Gene sequence:

>1038_bases
TTGTTGAGATGTACAAAATGCAATAGAGTTTATGAAGAAGATTTGAGAATTCAGTGCGAGTGTGAAGGAACTCTGTTGGT
TGAAAGAAAGTATTCATCCTTTGCTCCACAGAGAAGATATTTTGACATGAGAAGATATTTGCCCTATCTGCCTGTCAATG
AGAGATTTCTCCCCTATCTCCATCCTCCTGTAACACCTGTTAGTAAAGTTAAAAATGTCATATTTAAGTTGGAGTATCTT
CATCCCACGGGGTCTTTTAAGGACAGAGGAACTTATGTAACTGTTGCAAAACTTAAAGAGTTAAAAATTAAGGAGATTGT
GATAGATAGTTCTGGGAATGCTGCTATTAGCATGGCAGTATACTCAGCGTTCTCCAACATTAGAACTCACATTTTTGTCT
CATCTAATACTAGAAAGGAAAAACTCTCTTTGTTATCTTCATTTGGAGCAGAGCTTCATATAGTTGAAGGAGATAGAATG
AAAGTTCATGAAGAAGCCGTTAAGTACTCAAGGGAAAACAACATTCCTTATCTCTCCCACTGGTTGAATCCATATTTTCT
CGAGGGGACAAAAACAGTGGCATATGAAATCTATGAGCAGGTGGGAGTGCCTGAATATGTTGTAGTTCCAACAGGAAGTG
GAACGCTCTTCATAGGAATATGGAAGGGATTTAAGGAGTTGTTTGAAATGGGGGAGATATCTAGGCTCCCCAAAATGATA
GCTGTTCAAGCTAAAGGATTTGAAAGTTTGTGTAAAAGGAGTAATAGTGAGGCAAACGTCTTGGCTGATGGAATAGCTAT
ACCTAATCCACCCAGGAAAGAGGAGATGTTTCGGATTATTAAAGAGTCAAATGGGTCGTGCATAAGTATTGGGGAAAGGG
TGACTAGGCAAGCTCTTACTGAGCTCTATAGAATGGGATTTATCGTTGAACCTACGTCAGCGGTAGCATACGCGGCCCTT
AAATTTTTTGAAGATGAGGGAAAATCCTTCGTAGTCCCACTTACCGGAAGTGGTCTTAAACTTCACAGTTCCTTCTGA

Upstream 100 bases:

>100_bases
GCAGGGAAGACTTCAAGATACCCGTTGAAGAATTCGAGATGAAGATCGTGAGAAGGTAAATTTTTATTTTTTCTTTACTT
TTGTTTCTTGGTGGATTTAA

Downstream 100 bases:

>100_bases
AGAAATCGTTAAAATATCTCGCATAACAATATTTTTTGGTGAGAAAGATGATAAGGCGTGCTGTTGTTGCAGGGCAGTTT
TATCCAGATGATGCAGAGCT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MLRCTKCNRVYEEDLRIQCECEGTLLVERKYSSFAPQRRYFDMRRYLPYLPVNERFLPYLHPPVTPVSKVKNVIFKLEYL
HPTGSFKDRGTYVTVAKLKELKIKEIVIDSSGNAAISMAVYSAFSNIRTHIFVSSNTRKEKLSLLSSFGAELHIVEGDRM
KVHEEAVKYSRENNIPYLSHWLNPYFLEGTKTVAYEIYEQVGVPEYVVVPTGSGTLFIGIWKGFKELFEMGEISRLPKMI
AVQAKGFESLCKRSNSEANVLADGIAIPNPPRKEEMFRIIKESNGSCISIGERVTRQALTELYRMGFIVEPTSAVAYAAL
KFFEDEGKSFVVPLTGSGLKLHSSF

Sequences:

>Translated_345_residues
MLRCTKCNRVYEEDLRIQCECEGTLLVERKYSSFAPQRRYFDMRRYLPYLPVNERFLPYLHPPVTPVSKVKNVIFKLEYL
HPTGSFKDRGTYVTVAKLKELKIKEIVIDSSGNAAISMAVYSAFSNIRTHIFVSSNTRKEKLSLLSSFGAELHIVEGDRM
KVHEEAVKYSRENNIPYLSHWLNPYFLEGTKTVAYEIYEQVGVPEYVVVPTGSGTLFIGIWKGFKELFEMGEISRLPKMI
AVQAKGFESLCKRSNSEANVLADGIAIPNPPRKEEMFRIIKESNGSCISIGERVTRQALTELYRMGFIVEPTSAVAYAAL
KFFEDEGKSFVVPLTGSGLKLHSSF
>Mature_345_residues
MLRCTKCNRVYEEDLRIQCECEGTLLVERKYSSFAPQRRYFDMRRYLPYLPVNERFLPYLHPPVTPVSKVKNVIFKLEYL
HPTGSFKDRGTYVTVAKLKELKIKEIVIDSSGNAAISMAVYSAFSNIRTHIFVSSNTRKEKLSLLSSFGAELHIVEGDRM
KVHEEAVKYSRENNIPYLSHWLNPYFLEGTKTVAYEIYEQVGVPEYVVVPTGSGTLFIGIWKGFKELFEMGEISRLPKMI
AVQAKGFESLCKRSNSEANVLADGIAIPNPPRKEEMFRIIKESNGSCISIGERVTRQALTELYRMGFIVEPTSAVAYAAL
KFFEDEGKSFVVPLTGSGLKLHSSF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790207, Length=294, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 39235; Mature: 39235

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRCTKCNRVYEEDLRIQCECEGTLLVERKYSSFAPQRRYFDMRRYLPYLPVNERFLPYL
CCCCCCCCHHHHCCCEEEEEECCEEEEEECCHHCCCHHHHHHHHHCCCCCCCCCCCCCCC
HPPVTPVSKVKNVIFKLEYLHPTGSFKDRGTYVTVAKLKELKIKEIVIDSSGNAAISMAV
CCCCCHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEHHHHCEEEEEEEECCCCCEEHHHH
YSAFSNIRTHIFVSSNTRKEKLSLLSSFGAELHIVEGDRMKVHEEAVKYSRENNIPYLSH
HHHHHCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHH
WLNPYFLEGTKTVAYEIYEQVGVPEYVVVPTGSGTLFIGIWKGFKELFEMGEISRLPKMI
CCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCHHE
AVQAKGFESLCKRSNSEANVLADGIAIPNPPRKEEMFRIIKESNGSCISIGERVTRQALT
EEECCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ELYRMGFIVEPTSAVAYAALKFFEDEGKSFVVPLTGSGLKLHSSF
HHHHCCEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCC
>Mature Secondary Structure
MLRCTKCNRVYEEDLRIQCECEGTLLVERKYSSFAPQRRYFDMRRYLPYLPVNERFLPYL
CCCCCCCCHHHHCCCEEEEEECCEEEEEECCHHCCCHHHHHHHHHCCCCCCCCCCCCCCC
HPPVTPVSKVKNVIFKLEYLHPTGSFKDRGTYVTVAKLKELKIKEIVIDSSGNAAISMAV
CCCCCHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEHHHHCEEEEEEEECCCCCEEHHHH
YSAFSNIRTHIFVSSNTRKEKLSLLSSFGAELHIVEGDRMKVHEEAVKYSRENNIPYLSH
HHHHHCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHH
WLNPYFLEGTKTVAYEIYEQVGVPEYVVVPTGSGTLFIGIWKGFKELFEMGEISRLPKMI
CCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCHHE
AVQAKGFESLCKRSNSEANVLADGIAIPNPPRKEEMFRIIKESNGSCISIGERVTRQALT
EEECCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ELYRMGFIVEPTSAVAYAALKFFEDEGKSFVVPLTGSGLKLHSSF
HHHHCCEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]