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The map label for this gene is rpoH [H]

Identifier: 18977937

GI number: 18977937

Start: 1463013

End: 1463261

Strand: Reverse

Name: rpoH [H]

Synonym: PF1565

Alternate gene names: 18977937

Gene position: 1463261-1463013 (Counterclockwise)

Preceding gene: 33359567

Following gene: 18977936

Centisome position: 76.68

GC content: 38.96

Gene sequence:

>249_bases
GTGGCGGGGAAAAAGGAATTTAGCATATTTGATCATGTGTTAGTACCTGAACATAGAGTACTTAGTGAAGAGGAAAAGAA
AGCATTGCTAGAAAAGTACAAAATTACCTTAGCTCAATTACCTCAAATCAAAGCTAGCGATCCTGCTGTAAAAGCTTTGG
GAGCTAAGCCGGGAGATGTTATCGAAATTAAAAGGAAAAGTCCAACTGCGGGTGTCTACTACTACTATAGGGTTGTTGTT
GAAGACTAA

Upstream 100 bases:

>100_bases
TTTTAATAATGTTTATTAAGGTTGAGTAAAGCTTATATACTAGAGACTAAAGGGCTGGTGTAGATGACATTTGTAAAAAC
TTTTTGGGGGGCAATTCTCC

Downstream 100 bases:

>100_bases
AGTTCTGAAGGGGTGAGAAAATGAGAGGTCCGACTGTTGTAGATGTTACTCCCGACGATCTTTGGATTGTAATGGAGAGC
TATTGGCAAGAGAAAGGGCT

Product: DNA-directed RNA polymerase subunit H

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDVIEIKRKSPTAGVYYYYRVVV
ED

Sequences:

>Translated_82_residues
MAGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDVIEIKRKSPTAGVYYYYRVVV
ED
>Mature_81_residues
AGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDVIEIKRKSPTAGVYYYYRVVVE
D

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG2012

COG function: function code K; DNA-directed RNA polymerase, subunit H, RpoH/RPB5

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family [H]

Homologues:

Organism=Homo sapiens, GI14589951, Length=73, Percent_Identity=47.945205479452, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507947, Length=73, Percent_Identity=47.945205479452, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319630, Length=73, Percent_Identity=45.2054794520548, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922004, Length=74, Percent_Identity=45.945945945946, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020609
- InterPro:   IPR000783
- InterPro:   IPR020608
- ProDom:   PD005155 [H]

Pfam domain/function: PF01191 RNA_pol_Rpb5_C [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 9245; Mature: 9114

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS01110 RNA_POL_H_23KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDV
CCCCCCCCHHHEECCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCE
IEIKRKSPTAGVYYYYRVVVED
EEEECCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
AGKKEFSIFDHVLVPEHRVLSEEEKKALLEKYKITLAQLPQIKASDPAVKALGAKPGDV
CCCCCCCHHHEECCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCE
IEIKRKSPTAGVYYYYRVVVED
EEEECCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA