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The map label for this gene is yfiQ [C]

Identifier: 18977912

GI number: 18977912

Start: 1439252

End: 1440640

Strand: Direct

Name: yfiQ [C]

Synonym: PF1540

Alternate gene names: 18977912

Gene position: 1439252-1440640 (Clockwise)

Preceding gene: 18977911

Following gene: 18977915

Centisome position: 75.42

GC content: 43.27

Gene sequence:

>1389_bases
ATGAGTTTGGAGGCTCTTTTTAATCCAAAAAGCGTCGCAGTTATAGGAGCTTCTGCAAAGCCTGGGAAAATAGGATATGC
AATTATGAAAAATCTCATAGAATATGGGTATGAAGGCAAAATATACCCAGTAAACATCAAAGGCGGGGAAATAGAGATTA
ACGGAAGGAAATTCAAAGTCTACAAGAGCGTTCTTGAGATTCCTGATGAAGTAGATATGGCAGTCATTGTAGTTCCAGCT
AAGTTTGTCCCTCAGGTTCTAGAGGAATGTGGTCAAAAAGGCGTCAAGGTCGTCCCAATTATAAGCTCTGGATTTGGAGA
GCTAGGAGAAGAAGGAAAGAAAGTCGAGCAACAACTTGTCGAAACTGCCAGAAAATATGGAATGAGGATCCTTGGTCCTA
ACATCTTCGGAGTTGTATACACTCCAGCAAAGCTTAATGCAACATTCGGTCCAACTGACGTTCTCCCAGGGCCATTAGCA
CTAATTAGCCAAAGCGGTGCCCTTGGAATTGCACTAATGGGATGGACAATACTGGAGAAAATAGGACTTTCAGCCGTTGT
TAGCGTTGGGAATAAAGCCGACATTGACGATGCAGACCTTCTAGAGTTCTTCAAGGATGATGAGAATACGAGAGCTATTC
TAATTTACATGGAAGGTGTGAAAGATGGAAGGAGGTTCATGGAGGTAGCAAAAGAGGTTAGCAAGAAGAAGCCAATAATT
GTCATTAAAGCCGGAAGAAGCGAGAGAGGAGCAAAAGCAGCCGCTTCACACACGGGATCTCTTGCAGGTAGTGACAAAGT
TTATAGCGCAGCATTTAAGCAGAGTGGAGTCTTAAGAGCATATACCATTGGTGAAGCTTTTGACTGGGCAAGAGCTTTAA
GCAATCTACCTGAGCCACAAGGAGATAACGTTGTGATAATCACCAACGGAGGAGGAATTGGAGTAATGGCAACTGACGCC
GCAGAAGAAGAAGGCTTACACCTCTATGACAACCTTGAAGAGCTCAAGATATTCGCAAACCACATGCCACCATTTGGAAG
CTATAAGAATCCCGTTGACTTAACTGGAATGGCAGATGGAAAGAGTTATGAAGGTGCTATAAGGGATGCTCTTGCTCATC
CAGAAATGCACTCAATAGCAGTTCTCTATTGTCAGACTGCCGTCCTTGATCCAAGAGAACTGGCTGAGATAGTGATAAGA
GAGTACAACGAAAGTGGAAGAAAGAAGCCTCTTGTAGTTGCAATTGTGGGTGGTATAGAGGCAAAAGAAGCCATAGACAT
GCTAAACGAGAACGGAATTCCTGCATATCCAGAACCAGAAAGGGCAATAAAGGCATTATCAGCACTGTACAAGTGGAGCA
AGTGGAAAGCAAAACACAAAGAAAAGTAA

Upstream 100 bases:

>100_bases
GTTTAACATCTGCCGATCAAAAGTTCGTTAAAAGCAGAAGGATAAAGTTATAATATTAAGAGAGAACGGATAGATGGAAG
CAATTTCAGAGGTGATTTAA

Downstream 100 bases:

>100_bases
AGAAGAAATCAATGGGCGTTCTTTTTCTTCTTCCACTTCTTACTCCATCTATATTTCCTTAGCCTTCTGCTTCTACCGAA
TCCACAAGCTGCACAATAGC

Product: ADP forming acetyl coenzyme A synthetase

Products: ADP; phosphate; acetyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYKSVLEIPDEVDMAVIVVPA
KFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLA
LISQSGALGIALMGWTILEKIGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPII
VIKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGDNVVIITNGGGIGVMATDA
AEEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADGKSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIR
EYNESGRKKPLVVAIVGGIEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK

Sequences:

>Translated_462_residues
MSLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYKSVLEIPDEVDMAVIVVPA
KFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLA
LISQSGALGIALMGWTILEKIGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPII
VIKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGDNVVIITNGGGIGVMATDA
AEEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADGKSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIR
EYNESGRKKPLVVAIVGGIEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK
>Mature_461_residues
SLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYKSVLEIPDEVDMAVIVVPAK
FVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLAL
ISQSGALGIALMGWTILEKIGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIV
IKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGDNVVIITNGGGIGVMATDAA
EEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADGKSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIRE
YNESGRKKPLVVAIVGGIEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK

Specific function: Unknown

COG id: COG1042

COG function: function code C; Acyl-CoA synthetase (NDP forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yfiQ [H]

Homologues:

Organism=Escherichia coli, GI1788938, Length=462, Percent_Identity=31.6017316017316, Blast_Score=226, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014089
- InterPro:   IPR013650
- InterPro:   IPR003781
- InterPro:   IPR016040
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF02629 CoA_binding [H]

EC number: 6.2.1.13

Molecular weight: Translated: 49965; Mature: 49834

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKV
CCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCEEHH
YKSVLEIPDEVDMAVIVVPAKFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLV
HHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
ETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEK
HHHHHCCEEEECCCEEEEEECCCEECCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHH
IGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPII
HCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
VIKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQ
EEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCC
GDNVVIITNGGGIGVMATDAAEEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADG
CCCEEEEECCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCEEEECCCC
KSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIREYNESGRKKPLVVAIVGGIE
CCCCHHHHHHHCCCCHHHEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
AKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKV
CCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCEEHH
YKSVLEIPDEVDMAVIVVPAKFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLV
HHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
ETARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEK
HHHHHCCEEEECCCEEEEEECCCEECCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHH
IGLSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPII
HCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
VIKAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQ
EEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCC
GDNVVIITNGGGIGVMATDAAEEEGLHLYDNLEELKIFANHMPPFGSYKNPVDLTGMADG
CCCEEEEECCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCEEEECCCC
KSYEGAIRDALAHPEMHSIAVLYCQTAVLDPRELAEIVIREYNESGRKKPLVVAIVGGIE
CCCCHHHHHHHCCCCHHHEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
AKEAIDMLNENGIPAYPEPERAIKALSALYKWSKWKAKHKEK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetate; CoA

Specific reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]