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The map label for this gene is 18977759

Identifier: 18977759

GI number: 18977759

Start: 1300654

End: 1301496

Strand: Reverse

Name: 18977759

Synonym: PF1387

Alternate gene names: NA

Gene position: 1301496-1300654 (Counterclockwise)

Preceding gene: 18977760

Following gene: 18977754

Centisome position: 68.2

GC content: 38.55

Gene sequence:

>843_bases
GTGCACATCAGGCTGAGCTTTATAACTTTCTCTTTGATTTTATTTTTGGTGGTTGATATGGTAAAAATACCGAAGTCTCA
TCCACGATATTGGAGTCTTTTGTATAGAGAAAAAATAATTGAGGGGATGGAGAAAGGGATTACAGCCAAAGCAGGGCTTA
TTGCCCATGGAAGGGGAGAAGCATTTGACTATTTAATTGGAGAAAAAACAATCCCACCAGCAGAAACTGCAATGAGAGCT
GCAATTGCTAAATTACTCCTTGCGAAACACCCTGTAATTTCTGTAAACGGCAATGTTGCTGCTTTAGTTCCTAAAGAAAC
AGTTGAATTAGCAAAAGTTCTGAACGCAAAATTGGAGATTAACTTATTTTATAGAACTGAAGAGAGAGTTAAGAAAATTG
CTGAAGTCCTTTATGAGAATGGAGCCGATGAGGTTCTGGGAATTAACCCAACTAAAAGAATTCCAGGATTGGAGAGTGAG
AGGGGAAAGGTTGATGAAAATGGTATCTGGAAAGCTGATGTCATTTTGGTTCCTTTAGAAGATGGAGACAGAACAGAAGC
ATTATGTAGAATGGGAAAATTTGTAATAACTGTGGATTTAAACCCGCTCTCGAGAAGTGCCAGAATGGCTGATATAACAA
TAGTGGATAACATAGTTAGGGCTTATCCCAGGATGATAGAGCTCGCAAAAGAAATGAAGTCTCTCCCAAAAGAAGATCTA
GAGAAGATAGTGGCCACTTATGATAACTCAAAAGTTTTGAGTGAGGTTCTCATACACATTAGAGATAGGCTCACGAAGCT
TGCAGAGGGGGGAATCTGGAAAAAAGAAAAACTTGACATTTAA

Upstream 100 bases:

>100_bases
TTGTTCTGCCTCTGCTCATCTAAAATTGGGTGGAACGATAGTTAGATATACTTTGGAGATTTTCGATGATGAGCCTCCAT
CCCATGCTGAAGGGTGATGA

Downstream 100 bases:

>100_bases
AATGCCCCGACTAGTTTCCTCAGGCCCATAATTAATTCACTTTCGCTCTCTGCTTTTGAGACAACCAAGGGGACTCTTTC
TTTTTCTGCAATTTTTATGG

Product: hypothetical protein

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MHIRLSFITFSLILFLVVDMVKIPKSHPRYWSLLYREKIIEGMEKGITAKAGLIAHGRGEAFDYLIGEKTIPPAETAMRA
AIAKLLLAKHPVISVNGNVAALVPKETVELAKVLNAKLEINLFYRTEERVKKIAEVLYENGADEVLGINPTKRIPGLESE
RGKVDENGIWKADVILVPLEDGDRTEALCRMGKFVITVDLNPLSRSARMADITIVDNIVRAYPRMIELAKEMKSLPKEDL
EKIVATYDNSKVLSEVLIHIRDRLTKLAEGGIWKKEKLDI

Sequences:

>Translated_280_residues
MHIRLSFITFSLILFLVVDMVKIPKSHPRYWSLLYREKIIEGMEKGITAKAGLIAHGRGEAFDYLIGEKTIPPAETAMRA
AIAKLLLAKHPVISVNGNVAALVPKETVELAKVLNAKLEINLFYRTEERVKKIAEVLYENGADEVLGINPTKRIPGLESE
RGKVDENGIWKADVILVPLEDGDRTEALCRMGKFVITVDLNPLSRSARMADITIVDNIVRAYPRMIELAKEMKSLPKEDL
EKIVATYDNSKVLSEVLIHIRDRLTKLAEGGIWKKEKLDI
>Mature_280_residues
MHIRLSFITFSLILFLVVDMVKIPKSHPRYWSLLYREKIIEGMEKGITAKAGLIAHGRGEAFDYLIGEKTIPPAETAMRA
AIAKLLLAKHPVISVNGNVAALVPKETVELAKVLNAKLEINLFYRTEERVKKIAEVLYENGADEVLGINPTKRIPGLESE
RGKVDENGIWKADVILVPLEDGDRTEALCRMGKFVITVDLNPLSRSARMADITIVDNIVRAYPRMIELAKEMKSLPKEDL
EKIVATYDNSKVLSEVLIHIRDRLTKLAEGGIWKKEKLDI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction [H]

COG id: COG1701

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal pantothenate synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002855
- ProDom:   PD016827 [H]

Pfam domain/function: PF02006 DUF137 [H]

EC number: NA

Molecular weight: Translated: 31464; Mature: 31464

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIRLSFITFSLILFLVVDMVKIPKSHPRYWSLLYREKIIEGMEKGITAKAGLIAHGRGE
CEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCEEECCCCC
AFDYLIGEKTIPPAETAMRAAIAKLLLAKHPVISVNGNVAALVPKETVELAKVLNAKLEI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHHCCEEEE
NLFYRTEERVKKIAEVLYENGADEVLGINPTKRIPGLESERGKVDENGIWKADVILVPLE
EEEECCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
DGDRTEALCRMGKFVITVDLNPLSRSARMADITIVDNIVRAYPRMIELAKEMKSLPKEDL
CCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EKIVATYDNSKVLSEVLIHIRDRLTKLAEGGIWKKEKLDI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MHIRLSFITFSLILFLVVDMVKIPKSHPRYWSLLYREKIIEGMEKGITAKAGLIAHGRGE
CEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCEEECCCCC
AFDYLIGEKTIPPAETAMRAAIAKLLLAKHPVISVNGNVAALVPKETVELAKVLNAKLEI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHHCCEEEE
NLFYRTEERVKKIAEVLYENGADEVLGINPTKRIPGLESERGKVDENGIWKADVILVPLE
EEEECCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
DGDRTEALCRMGKFVITVDLNPLSRSARMADITIVDNIVRAYPRMIELAKEMKSLPKEDL
CCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EKIVATYDNSKVLSEVLIHIRDRLTKLAEGGIWKKEKLDI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]