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The map label for this gene is 18977634

Identifier: 18977634

GI number: 18977634

Start: 1194449

End: 1195240

Strand: Direct

Name: 18977634

Synonym: PF1262

Alternate gene names: NA

Gene position: 1194449-1195240 (Clockwise)

Preceding gene: 18977628

Following gene: 18977635

Centisome position: 62.59

GC content: 35.73

Gene sequence:

>792_bases
ATGTGCATTATTTTTCTTTTTCCTCTCTTTATTTCCTCAATTTTCCTATTTTTCTTCCTTAATATGGAGAGCATCAATAA
ATTTTTGTGTTCATGTTTTTATTTATTTAGGGGTGAAAACGTGAAGAAGAGACTTCATCTAATTATAGCAGACTCTGAAC
TTGAGCTAGTTCCTGAGAGTATAATTGATCATCCAGCCATTGTGAATTATGCCAAGAGAAGAAAAAAGAAGCCAGAAAAA
ATAATCCTTGATTCTACATATCATCATGCAGCACTGAGACAGTTAGAGGATGGAGAAAGGAGGGGAAGGCCCGATATTGT
TCATATATGCCTATTAAATGCTTTGGATAGTATCCTTAATAAAGAGGATAGGCTTAGAGTTTACGTTCACACAAGGAATG
ATGAAGTGATTTACGTAGATCCTTCTACTAGACTTCCAAGAAATTATAACAGGTTTATTGGCCTTATGGAGAGTTTGTTT
GAGAAGAAAGTAGTTCCGGAGGATTTACAGCTCTTAAGATTGGAAAAGAAAACCTTAGCTGAGTTAATAAATGAGATATC
TCCAGATGCTGTATTTATAATGCACGAAAATGGAGAGTTTATGATACCGAAACACTTTGGAAAACTGTTGGCTAGCTTTA
AAAAGCCTGTTGTTATAGTTGGGGGCTTTCCTCATGGAGACTTCAGAAGCAAAGTGGAGGGAGTGAAGATAAGCCTTTAT
AGAGAACCATTAATGGCCTGGACAATTGTAAATGAGGTCATAGTTTCTTATGAGTGGGAGGTTATAAAGTAA

Upstream 100 bases:

>100_bases
TAGGTTGTCGACTAAATCTCCAGTGTGAATTATCACGTCAGGCTGAGTTTCTGCTATTAGCTCTCCAAGAAACTTGTAGA
CACTTCTAGGGGTATCACTT

Downstream 100 bases:

>100_bases
AAAAGATTTATAATATTTTGTATTGAGAAAGACAAATAAAGATGAACGGGGGGAAGGCTCGATGAATAGGAGCTTGTACT
TGATTTTTATAATTGTAGGA

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MCIIFLFPLFISSIFLFFFLNMESINKFLCSCFYLFRGENVKKRLHLIIADSELELVPESIIDHPAIVNYAKRRKKKPEK
IILDSTYHHAALRQLEDGERRGRPDIVHICLLNALDSILNKEDRLRVYVHTRNDEVIYVDPSTRLPRNYNRFIGLMESLF
EKKVVPEDLQLLRLEKKTLAELINEISPDAVFIMHENGEFMIPKHFGKLLASFKKPVVIVGGFPHGDFRSKVEGVKISLY
REPLMAWTIVNEVIVSYEWEVIK

Sequences:

>Translated_263_residues
MCIIFLFPLFISSIFLFFFLNMESINKFLCSCFYLFRGENVKKRLHLIIADSELELVPESIIDHPAIVNYAKRRKKKPEK
IILDSTYHHAALRQLEDGERRGRPDIVHICLLNALDSILNKEDRLRVYVHTRNDEVIYVDPSTRLPRNYNRFIGLMESLF
EKKVVPEDLQLLRLEKKTLAELINEISPDAVFIMHENGEFMIPKHFGKLLASFKKPVVIVGGFPHGDFRSKVEGVKISLY
REPLMAWTIVNEVIVSYEWEVIK
>Mature_263_residues
MCIIFLFPLFISSIFLFFFLNMESINKFLCSCFYLFRGENVKKRLHLIIADSELELVPESIIDHPAIVNYAKRRKKKPEK
IILDSTYHHAALRQLEDGERRGRPDIVHICLLNALDSILNKEDRLRVYVHTRNDEVIYVDPSTRLPRNYNRFIGLMESLF
EKKVVPEDLQLLRLEKKTLAELINEISPDAVFIMHENGEFMIPKHFGKLLASFKKPVVIVGGFPHGDFRSKVEGVKISLY
REPLMAWTIVNEVIVSYEWEVIK

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing [H]

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family [H]

Homologues:

Organism=Homo sapiens, GI194328699, Length=188, Percent_Identity=32.9787234042553, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17555712, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323215, Length=143, Percent_Identity=31.4685314685315, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639698, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005304 [H]

Pfam domain/function: PF03587 EMG1 [H]

EC number: NA

Molecular weight: Translated: 30763; Mature: 30763

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIIFLFPLFISSIFLFFFLNMESINKFLCSCFYLFRGENVKKRLHLIIADSELELVPES
CEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCHHHHCCHH
IIDHPAIVNYAKRRKKKPEKIILDSTYHHAALRQLEDGERRGRPDIVHICLLNALDSILN
HCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
KEDRLRVYVHTRNDEVIYVDPSTRLPRNYNRFIGLMESLFEKKVVPEDLQLLRLEKKTLA
CCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ELINEISPDAVFIMHENGEFMIPKHFGKLLASFKKPVVIVGGFPHGDFRSKVEGVKISLY
HHHHHCCCCEEEEEECCCCEECHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCEEEEEE
REPLMAWTIVNEVIVSYEWEVIK
HHHHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure
MCIIFLFPLFISSIFLFFFLNMESINKFLCSCFYLFRGENVKKRLHLIIADSELELVPES
CEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCHHHHCCHH
IIDHPAIVNYAKRRKKKPEKIILDSTYHHAALRQLEDGERRGRPDIVHICLLNALDSILN
HCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
KEDRLRVYVHTRNDEVIYVDPSTRLPRNYNRFIGLMESLFEKKVVPEDLQLLRLEKKTLA
CCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ELINEISPDAVFIMHENGEFMIPKHFGKLLASFKKPVVIVGGFPHGDFRSKVEGVKISLY
HHHHHCCCCEEEEEECCCCEECHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCEEEEEE
REPLMAWTIVNEVIVSYEWEVIK
HHHHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA