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The map label for this gene is 18977626

Identifier: 18977626

GI number: 18977626

Start: 1188413

End: 1190149

Strand: Direct

Name: 18977626

Synonym: PF1254

Alternate gene names: NA

Gene position: 1188413-1190149 (Clockwise)

Preceding gene: 18977624

Following gene: 18977627

Centisome position: 62.28

GC content: 43.06

Gene sequence:

>1737_bases
GTGCCATGGCATTTCACCCAGATAAAATATAATCCTGGGAGTTATAAACCTATATTTTATGATTTACAAAGTTGTAAAAC
CAAATTTTTGTCATTTTTCGGCAATTGTCCTGGAGAAAGTTTATATATCGGTGAAAATATGGAGATATTTGTAAAATTCT
GGAGGTGGTCACGAATGGAGCAGAGAGATAGGTGGGCAACAAAAATTGGACTTATTTTAGCGATGGCAGGAAATGCCATT
GGTCTAGGAAACTTCGTCAGGTTCCCAACCCAGGTTGCTGGGAACGGTGGAGGAGCATTCATGGTTCCTTACTTCTTGGC
ACTGTTCTTCCTTGGAATTCCAGTGATGTGGGTAGAGTGGGTGCAGGGAAGATATGGAGGTAAATACGGTCACGGAACAT
TGGGCCCAACCTTTTATCTGATGGCAAGAGAAACCCTAAAGCCAAGGGGTGCACTATTCTTCGGTCTCATTGGTGGAGCT
CTAGCATTTGCAACAACAACTCTACTTAACAGCTATTACCTTCACCTAATTGGATGGTCGGCAGCTTACTCATGGTTTAG
CATTAGTGGAGCTTATTTCAATGTGGAGAATACGGCAGAGTTCTTTGCTAGCTACCTCAGTAACCATGGACTGGTGTTCT
TATTCTGGGGCATTACTGTGGTCTTACTAGCAATAGCAGTTGGCCAAGGTGTAAGCAAGGGAATTGAGAGATGGGTCAAG
GTAATGATGCCACTATTGTACATATTCGCAATCATTTTAGTTATCTACGTCTTTGCATTGGGATCACCCCTCGGAGATCC
CAACTGGTCCACAATTAAGGGATTCGAGTTCATCTGGTCACCAAACTGGGGCTATCTAAAGGATCACCTATGGGAAGTAA
TGCTTGCGGCAAGTGGTCAGATATTCTTTACACTCTCTCTCGGAATGGGTATTATACAGAACTATGCTTCGTATCTTGGA
CCAAAAGATGATGTTGCACTCTCAGGATTAGCTACAGTTTCACTGAACGAGTTTGCTGAAGTTGTTCTCGGTGGTTCAAT
TGCAGTTCCATTGGCTGTAGCATACGCTCCAAAGATTGTGCCGGAAGATGTTCTTGCCCAGGGTAGCAATGCTGCATTAG
CATGGATTTCAGAGAACTTTGGACTTGGATTCTCATACACAAGCCTTCCAAACATATTTGTTCAGATGGGAACTGCAGGT
AGGTTCTTTGGAGCCTTATGGTTCCTCCTCCTCTGGTTTGCAGGATTTACTTCAGCAATAGCTATGTACAACTATCTAAC
GGCTTTACTGGAGGAAGATCTAGGAATATCAAGAAAGACTGGAACTTGGATTGTGTTCGTCATATACTTCCTCCTTGGAA
TCCCAGTAGTGTACATTAGCGGTTACCTTGATCAGGTAGATGCATGGATAAACTTCCAGTTAGCATTACTTGCACTGTTT
GACATAATAGTTGGAGTATGGCTGTTCAAGCCTGACAACTTCTGGAGGGAACTACACGAGGGAGCATACATCAACGTTCC
AACAATCTACAAGTGGATTACCGTAATAATTGCTCCAATTTTCATCGCTCTTCCACTGTTCGGAACATTCTCTGACCTAG
TTTCCAAGACATTAGAAACACCAGCAAAGATCGCAATAGTGGCAATGCTCCTCCTTGGTGCAATCGAAACCTACTATGCA
ATTAAGAAGAAGTACGGAGAAGAGCTAGCGAAGAACGAAGTGATAATCAAAGTGTGA

Upstream 100 bases:

>100_bases
GGCTCTCCAATTCCCAATGAAATTACATCCTTCATGCCAGCGGCCAAATCGAAGAGCTTCCTAATCTCAGAGGGATTAAC
TAAATCAAGCTTGTCGCTAA

Downstream 100 bases:

>100_bases
GGTGAAGAATATGTGGGCCGTGTACATGATAGTTGCGTGGCTGATAATATTCATCATGATGGGCTGGAGTATAAGTAAGC
TCATGAAGGCCGAACAAGCA

Product: putative sodium dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MPWHFTQIKYNPGSYKPIFYDLQSCKTKFLSFFGNCPGESLYIGENMEIFVKFWRWSRMEQRDRWATKIGLILAMAGNAI
GLGNFVRFPTQVAGNGGGAFMVPYFLALFFLGIPVMWVEWVQGRYGGKYGHGTLGPTFYLMARETLKPRGALFFGLIGGA
LAFATTTLLNSYYLHLIGWSAAYSWFSISGAYFNVENTAEFFASYLSNHGLVFLFWGITVVLLAIAVGQGVSKGIERWVK
VMMPLLYIFAIILVIYVFALGSPLGDPNWSTIKGFEFIWSPNWGYLKDHLWEVMLAASGQIFFTLSLGMGIIQNYASYLG
PKDDVALSGLATVSLNEFAEVVLGGSIAVPLAVAYAPKIVPEDVLAQGSNAALAWISENFGLGFSYTSLPNIFVQMGTAG
RFFGALWFLLLWFAGFTSAIAMYNYLTALLEEDLGISRKTGTWIVFVIYFLLGIPVVYISGYLDQVDAWINFQLALLALF
DIIVGVWLFKPDNFWRELHEGAYINVPTIYKWITVIIAPIFIALPLFGTFSDLVSKTLETPAKIAIVAMLLLGAIETYYA
IKKKYGEELAKNEVIIKV

Sequences:

>Translated_578_residues
MPWHFTQIKYNPGSYKPIFYDLQSCKTKFLSFFGNCPGESLYIGENMEIFVKFWRWSRMEQRDRWATKIGLILAMAGNAI
GLGNFVRFPTQVAGNGGGAFMVPYFLALFFLGIPVMWVEWVQGRYGGKYGHGTLGPTFYLMARETLKPRGALFFGLIGGA
LAFATTTLLNSYYLHLIGWSAAYSWFSISGAYFNVENTAEFFASYLSNHGLVFLFWGITVVLLAIAVGQGVSKGIERWVK
VMMPLLYIFAIILVIYVFALGSPLGDPNWSTIKGFEFIWSPNWGYLKDHLWEVMLAASGQIFFTLSLGMGIIQNYASYLG
PKDDVALSGLATVSLNEFAEVVLGGSIAVPLAVAYAPKIVPEDVLAQGSNAALAWISENFGLGFSYTSLPNIFVQMGTAG
RFFGALWFLLLWFAGFTSAIAMYNYLTALLEEDLGISRKTGTWIVFVIYFLLGIPVVYISGYLDQVDAWINFQLALLALF
DIIVGVWLFKPDNFWRELHEGAYINVPTIYKWITVIIAPIFIALPLFGTFSDLVSKTLETPAKIAIVAMLLLGAIETYYA
IKKKYGEELAKNEVIIKV
>Mature_577_residues
PWHFTQIKYNPGSYKPIFYDLQSCKTKFLSFFGNCPGESLYIGENMEIFVKFWRWSRMEQRDRWATKIGLILAMAGNAIG
LGNFVRFPTQVAGNGGGAFMVPYFLALFFLGIPVMWVEWVQGRYGGKYGHGTLGPTFYLMARETLKPRGALFFGLIGGAL
AFATTTLLNSYYLHLIGWSAAYSWFSISGAYFNVENTAEFFASYLSNHGLVFLFWGITVVLLAIAVGQGVSKGIERWVKV
MMPLLYIFAIILVIYVFALGSPLGDPNWSTIKGFEFIWSPNWGYLKDHLWEVMLAASGQIFFTLSLGMGIIQNYASYLGP
KDDVALSGLATVSLNEFAEVVLGGSIAVPLAVAYAPKIVPEDVLAQGSNAALAWISENFGLGFSYTSLPNIFVQMGTAGR
FFGALWFLLLWFAGFTSAIAMYNYLTALLEEDLGISRKTGTWIVFVIYFLLGIPVVYISGYLDQVDAWINFQLALLALFD
IIVGVWLFKPDNFWRELHEGAYINVPTIYKWITVIIAPIFIALPLFGTFSDLVSKTLETPAKIAIVAMLLLGAIETYYAI
KKKYGEELAKNEVIIKV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=487, Percent_Identity=25.4620123203285, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI7657587, Length=520, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI197276623, Length=492, Percent_Identity=24.5934959349593, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI54607094, Length=492, Percent_Identity=24.5934959349593, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI21361581, Length=488, Percent_Identity=24.3852459016393, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI194018524, Length=311, Percent_Identity=29.5819935691318, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI197276625, Length=126, Percent_Identity=36.5079365079365, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI58219014, Length=352, Percent_Identity=26.7045454545455, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI171184408, Length=495, Percent_Identity=23.8383838383838, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI171184406, Length=495, Percent_Identity=23.8383838383838, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI171184404, Length=495, Percent_Identity=23.8383838383838, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI33354281, Length=356, Percent_Identity=23.876404494382, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI134304856, Length=301, Percent_Identity=27.2425249169435, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI67782315, Length=97, Percent_Identity=37.1134020618557, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17542050, Length=122, Percent_Identity=35.2459016393443, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995588, Length=64, Percent_Identity=46.875, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=69, Percent_Identity=42.0289855072464, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI133952791, Length=129, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921936, Length=498, Percent_Identity=21.8875502008032, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17136952, Length=518, Percent_Identity=23.3590733590734, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364394, Length=477, Percent_Identity=23.2704402515723, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574704, Length=477, Percent_Identity=23.2704402515723, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136950, Length=477, Percent_Identity=23.2704402515723, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574702, Length=477, Percent_Identity=23.2704402515723, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639514, Length=529, Percent_Identity=24.3856332703214, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221329674, Length=530, Percent_Identity=24.5283018867925, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639516, Length=311, Percent_Identity=25.08038585209, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45550877, Length=134, Percent_Identity=32.8358208955224, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45551183, Length=145, Percent_Identity=32.4137931034483, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 64484; Mature: 64353

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWHFTQIKYNPGSYKPIFYDLQSCKTKFLSFFGNCPGESLYIGENMEIFVKFWRWSRME
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHH
QRDRWATKIGLILAMAGNAIGLGNFVRFPTQVAGNGGGAFMVPYFLALFFLGIPVMWVEW
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHCCCCCCEEHHHHHHHHHHHCCHHHHHHH
VQGRYGGKYGHGTLGPTFYLMARETLKPRGALFFGLIGGALAFATTTLLNSYYLHLIGWS
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYSWFSISGAYFNVENTAEFFASYLSNHGLVFLFWGITVVLLAIAVGQGVSKGIERWVK
HHHHHHEECCEEEECCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VMMPLLYIFAIILVIYVFALGSPLGDPNWSTIKGFEFIWSPNWGYLKDHLWEVMLAASGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
IFFTLSLGMGIIQNYASYLGPKDDVALSGLATVSLNEFAEVVLGGSIAVPLAVAYAPKIV
EEEEEHHHHHHHHHHHHHCCCCCCHHHCCHHEEEHHHHHHHHHCCCHHHHHHHHHCCCCC
PEDVLAQGSNAALAWISENFGLGFSYTSLPNIFVQMGTAGRFFGALWFLLLWFAGFTSAI
CHHHHCCCCCCEEEEEECCCCCCEEHHCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHH
AMYNYLTALLEEDLGISRKTGTWIVFVIYFLLGIPVVYISGYLDQVDAWINFQLALLALF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIVGVWLFKPDNFWRELHEGAYINVPTIYKWITVIIAPIFIALPLFGTFSDLVSKTLET
HHHHHHHHCCCHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAKIAIVAMLLLGAIETYYAIKKKYGEELAKNEVIIKV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure 
PWHFTQIKYNPGSYKPIFYDLQSCKTKFLSFFGNCPGESLYIGENMEIFVKFWRWSRME
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHH
QRDRWATKIGLILAMAGNAIGLGNFVRFPTQVAGNGGGAFMVPYFLALFFLGIPVMWVEW
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHCCCCCCEEHHHHHHHHHHHCCHHHHHHH
VQGRYGGKYGHGTLGPTFYLMARETLKPRGALFFGLIGGALAFATTTLLNSYYLHLIGWS
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYSWFSISGAYFNVENTAEFFASYLSNHGLVFLFWGITVVLLAIAVGQGVSKGIERWVK
HHHHHHEECCEEEECCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VMMPLLYIFAIILVIYVFALGSPLGDPNWSTIKGFEFIWSPNWGYLKDHLWEVMLAASGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
IFFTLSLGMGIIQNYASYLGPKDDVALSGLATVSLNEFAEVVLGGSIAVPLAVAYAPKIV
EEEEEHHHHHHHHHHHHHCCCCCCHHHCCHHEEEHHHHHHHHHCCCHHHHHHHHHCCCCC
PEDVLAQGSNAALAWISENFGLGFSYTSLPNIFVQMGTAGRFFGALWFLLLWFAGFTSAI
CHHHHCCCCCCEEEEEECCCCCCEEHHCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHH
AMYNYLTALLEEDLGISRKTGTWIVFVIYFLLGIPVVYISGYLDQVDAWINFQLALLALF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIVGVWLFKPDNFWRELHEGAYINVPTIYKWITVIIAPIFIALPLFGTFSDLVSKTLET
HHHHHHHHCCCHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAKIAIVAMLLLGAIETYYAIKKKYGEELAKNEVIIKV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]