| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
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The map label for this gene is dppD [H]
Identifier: 18977584
GI number: 18977584
Start: 1153573
End: 1154541
Strand: Direct
Name: dppD [H]
Synonym: PF1212
Alternate gene names: 18977584
Gene position: 1153573-1154541 (Clockwise)
Preceding gene: 18977583
Following gene: 18977585
Centisome position: 60.45
GC content: 46.13
Gene sequence:
>969_bases ATGCTTAAGGTTGAGAACCTCAAGATTTACTATTCAACCCCAATCGGATTTGTAAAAGCAGTTGATGGAGTAAGTTTCGA AGTCAAGAAGGGGGAAGTGTTTGGAATTGCTGGAGAGAGCGGTTGTGGGAAATCAACCCTCGTCCACTCCCTAATCCTCA GAAAACCACCAATGACACACAAGGGTGGGAAGGCAATCTTCAAGGGGAAGGATTTAATGAAACTCTCGAGGGAGGAGGCA AGAAAAATCCAATACAAGGAGTTATCAATAATCCCACAATACGCAATGAACGCCCTAAACCCAACGAAAAAAATCAAGGA CATAGTATGGGATTTAGCAAGGGAACACGGCATGCAAGATAGAGAGGAAGTCGAAAAACTCTTGAAAGAAAGACTAAGCA TGGTAAAACTCTCACCAAAGGTCGCCGAAATGTACCCAGTGGAATTGAGTGGAGGAATGAGGCAGAGGGCCACAATGGTA GTCTCAACCCTCCTAAACCCAGACTTGCTAATTGCTGATGAGCTAACATCAGCCCTAGACGTGACAACACAAAGAGTTGT CATTGAATTACTCCACTACTTCATGCAGGAGGGGATTGTAAAATCAATAATCTTCGTTACACACGATCTAGCCTTGCTAA AACAGATTGCAGACAGGGTTATGGTGATGTACGCGGGGAAGGTTGTTGAAATCGGGCCAATGGAGGAGGTTTTAGAATCC CCAGCCCACCCCTACACGCAAATGCTCCTCGACTCCCTCCCAAGAATGGGTGTACACTACAAGAGGCAAAAACTCCACGG AATCCCAGGTTATCCAATAAGCCTACTAAACCCACCCCAAGGTTGCAGATTCTACACAAGATGCCCCTACGCAATGGAAC ACTGTCCAAAAATAGAGCCAAAATTAGTCCAAGTCTCCAAAGAGCATTACGCAGCCTGCCACCTCCTCGGGGGTGAGGGA AGTGCTTGA
Upstream 100 bases:
>100_bases ATTCCCCCAGGATTGGTCATAGCCATCCTAATTACCGGGCTATATATGATCAATCTTGGTCTTGAGGAGGTGTTTAATCC GAGGTTGAGGAGGGAGTGAG
Downstream 100 bases:
>100_bases ACTCGAGAATGTGACAAAAACCTTCACCTCGGGACTCTTTGGTGGATATGAGATTAGGGCAGTGGATGGAGTATCATTCA AGGTTGAGGAGGGTGAGATA
Product: putative peptide ABC uptake protein
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 322; Mature: 322
Protein sequence:
>322_residues MLKVENLKIYYSTPIGFVKAVDGVSFEVKKGEVFGIAGESGCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSREEA RKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMV VSTLLNPDLLIADELTSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVLES PAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGGEG SA
Sequences:
>Translated_322_residues MLKVENLKIYYSTPIGFVKAVDGVSFEVKKGEVFGIAGESGCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSREEA RKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMV VSTLLNPDLLIADELTSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVLES PAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGGEG SA >Mature_322_residues MLKVENLKIYYSTPIGFVKAVDGVSFEVKKGEVFGIAGESGCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSREEA RKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMV VSTLLNPDLLIADELTSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVLES PAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGGEG SA
Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI47078218, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI45446740, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI42490749, Length=248, Percent_Identity=27.8225806451613, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI21536376, Length=236, Percent_Identity=27.9661016949153, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI27436953, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI11967971, Length=226, Percent_Identity=24.7787610619469, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI48994883, Length=315, Percent_Identity=37.7777777777778, Blast_Score=211, Evalue=4e-56, Organism=Escherichia coli, GI1787500, Length=314, Percent_Identity=36.9426751592357, Blast_Score=195, Evalue=4e-51, Organism=Escherichia coli, GI1789962, Length=309, Percent_Identity=36.8932038834951, Blast_Score=193, Evalue=1e-50, Organism=Escherichia coli, GI1789963, Length=317, Percent_Identity=35.3312302839117, Blast_Score=192, Evalue=2e-50, Organism=Escherichia coli, GI1787759, Length=320, Percent_Identity=35.9375, Blast_Score=181, Evalue=4e-47, Organism=Escherichia coli, GI1787548, Length=327, Percent_Identity=33.0275229357798, Blast_Score=167, Evalue=8e-43, Organism=Escherichia coli, GI145693107, Length=266, Percent_Identity=34.9624060150376, Blast_Score=160, Evalue=1e-40, Organism=Escherichia coli, GI1787758, Length=285, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=1e-39, Organism=Escherichia coli, GI1788506, Length=259, Percent_Identity=33.2046332046332, Blast_Score=145, Evalue=4e-36, Organism=Escherichia coli, GI48994997, Length=253, Percent_Identity=31.6205533596838, Blast_Score=132, Evalue=3e-32, Organism=Escherichia coli, GI1786398, Length=252, Percent_Identity=31.3492063492063, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=34.297520661157, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1789891, Length=210, Percent_Identity=34.7619047619048, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1787547, Length=255, Percent_Identity=30.9803921568627, Blast_Score=104, Evalue=9e-24, Organism=Escherichia coli, GI1789890, Length=255, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1788225, Length=240, Percent_Identity=27.5, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87081791, Length=267, Percent_Identity=29.2134831460674, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787029, Length=256, Percent_Identity=26.953125, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI87081834, Length=230, Percent_Identity=31.304347826087, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789991, Length=236, Percent_Identity=27.5423728813559, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786698, Length=221, Percent_Identity=30.316742081448, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1788761, Length=288, Percent_Identity=25, Blast_Score=82, Evalue=6e-17, Organism=Escherichia coli, GI1786345, Length=218, Percent_Identity=31.651376146789, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1790739, Length=255, Percent_Identity=27.843137254902, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI87081709, Length=232, Percent_Identity=25.8620689655172, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=25.4826254826255, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787972, Length=223, Percent_Identity=31.390134529148, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI48995001, Length=255, Percent_Identity=28.6274509803922, Blast_Score=78, Evalue=9e-16, Organism=Escherichia coli, GI1788450, Length=244, Percent_Identity=25, Blast_Score=75, Evalue=7e-15, Organism=Escherichia coli, GI1787712, Length=230, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1788644, Length=242, Percent_Identity=26.0330578512397, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789873, Length=233, Percent_Identity=26.6094420600858, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI48994943, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786872, Length=249, Percent_Identity=30.1204819277108, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI87082267, Length=259, Percent_Identity=26.2548262548263, Blast_Score=73, Evalue=3e-14, Organism=Escherichia coli, GI1787112, Length=245, Percent_Identity=28.1632653061224, Blast_Score=72, Evalue=7e-14, Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=27.3109243697479, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI87081782, Length=229, Percent_Identity=25.764192139738, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI1786703, Length=210, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787105, Length=241, Percent_Identity=26.9709543568465, Blast_Score=70, Evalue=3e-13, Organism=Escherichia coli, GI1789586, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786319, Length=243, Percent_Identity=27.9835390946502, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787792, Length=239, Percent_Identity=26.3598326359833, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787370, Length=240, Percent_Identity=26.25, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1788002, Length=225, Percent_Identity=29.7777777777778, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1786563, Length=241, Percent_Identity=29.045643153527, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1787143, Length=242, Percent_Identity=25.6198347107438, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=29.1845493562232, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17567265, Length=229, Percent_Identity=29.2576419213974, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193208177, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115533608, Length=231, Percent_Identity=25.1082251082251, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567269, Length=245, Percent_Identity=27.3469387755102, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71983523, Length=235, Percent_Identity=24.2553191489362, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71983510, Length=235, Percent_Identity=24.2553191489362, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71983516, Length=235, Percent_Identity=24.2553191489362, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17543740, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71984940, Length=227, Percent_Identity=28.1938325991189, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17558664, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=237, Percent_Identity=23.6286919831224, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324985, Length=239, Percent_Identity=24.6861924686192, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI85726357, Length=234, Percent_Identity=26.4957264957265, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI221512771, Length=213, Percent_Identity=25.8215962441315, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI116007328, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28574150, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24643674, Length=208, Percent_Identity=26.4423076923077, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24659289, Length=232, Percent_Identity=28.448275862069, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 36159; Mature: 36159
Theoretical pI: Translated: 9.18; Mature: 9.18
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 5.0 %Met (Translated Protein) 6.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 5.0 %Met (Mature Protein) 6.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLKVENLKIYYSTPIGFVKAVDGVSFEVKKGEVFGIAGESGCGKSTLVHSLILRKPPMTH CCEEEEEEEEEECCCHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCCCCCC KGGKAIFKGKDLMKLSREEARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQD CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC REEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMVVSTLLNPDLLIADELTSALD HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH VTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVLES HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHCC PAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEP CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCCEEHCCCCHHHHHCCCCCH KLVQVSKEHYAACHLLGGEGSA HHHHHHHHHHHEEEEECCCCCC >Mature Secondary Structure MLKVENLKIYYSTPIGFVKAVDGVSFEVKKGEVFGIAGESGCGKSTLVHSLILRKPPMTH CCEEEEEEEEEECCCHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCCCCCC KGGKAIFKGKDLMKLSREEARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQD CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC REEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMVVSTLLNPDLLIADELTSALD HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH VTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVLES HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHCC PAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEP CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCCEEHCCCCHHHHHCCCCCH KLVQVSKEHYAACHLLGGEGSA HHHHHHHHHHHEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 1766370; 9384377 [H]