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The map label for this gene is ubiE [C]

Identifier: 18977547

GI number: 18977547

Start: 1122487

End: 1123119

Strand: Direct

Name: ubiE [C]

Synonym: PF1175

Alternate gene names: 18977547

Gene position: 1122487-1123119 (Clockwise)

Preceding gene: 18977546

Following gene: 18977548

Centisome position: 58.82

GC content: 40.28

Gene sequence:

>633_bases
ATGCCCAAAATAGAACCTTTTGAAAAGTACACTGAGAGATACGAGGAGTGGTTTGAAAGAAATAAATTTGCATACCTCAG
TGAGCTTAATGCCCTGAAATCTCTTCTTCCTACCAGAGAATGTGTTGAAGTGGGAATAGGTAGTGGAAGGTTTGCGGCTC
CCCTGGGAATTAAGATGGGGGTAGAACCTTCTAAAAAGATGGCTGAAATAGCTAGGAAAAGAGGGATAAGGGTTATAGAA
GGTGTCGCAGAAAATCTTCCCTTTGAAGACAACTCGTTAGATTGTATCCTTATGGTGACAACAATATGCTTTGTGGACGA
TCCAGAGAAAGCTATAAAAGAAGCGTACAGAGTCCTCAAACCGGGAGGTTACATAGTAATTGGCTTTGTGGATAAGGAGA
GTTTAATAGGAAGGGAGTATGAAAAGAGAAAGGACAAAAGTGTTTTCTACAGAGACGCAAGATTTTTCTCTGCAAGGGAA
ATTATGGAACTTTTAGAACGCAATGGATTCAAAATTGATGGAGTTGTCCAAACTTTGTTCAAAAAATTAGATGAGATTCG
CGATGTTGAACCAGTAGAAGAAGGGTATGGAAGGGGAAGCTTCGTCGTTATAAGAGCCAAGAAGGTGGTTTAG

Upstream 100 bases:

>100_bases
AGAGGTACGGAAATTTGGATAAAAAAATTCTTGCTTACTTATTCGGACTATCAAAAGGAGTTAACATGGAGAAATTCAAA
GAATACTTGGAGGATGAATG

Downstream 100 bases:

>100_bases
ATGGATCTAGTTGAAAAAGTAAAGGAGCTTTGCTTAGAATTGGAAGAAGAAAACTTAGCAAAAGCAATTGAGAGATTCAT
AACTCTAACCCATGGAATCG

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MPKIEPFEKYTERYEEWFERNKFAYLSELNALKSLLPTRECVEVGIGSGRFAAPLGIKMGVEPSKKMAEIARKRGIRVIE
GVAENLPFEDNSLDCILMVTTICFVDDPEKAIKEAYRVLKPGGYIVIGFVDKESLIGREYEKRKDKSVFYRDARFFSARE
IMELLERNGFKIDGVVQTLFKKLDEIRDVEPVEEGYGRGSFVVIRAKKVV

Sequences:

>Translated_210_residues
MPKIEPFEKYTERYEEWFERNKFAYLSELNALKSLLPTRECVEVGIGSGRFAAPLGIKMGVEPSKKMAEIARKRGIRVIE
GVAENLPFEDNSLDCILMVTTICFVDDPEKAIKEAYRVLKPGGYIVIGFVDKESLIGREYEKRKDKSVFYRDARFFSARE
IMELLERNGFKIDGVVQTLFKKLDEIRDVEPVEEGYGRGSFVVIRAKKVV
>Mature_209_residues
PKIEPFEKYTERYEEWFERNKFAYLSELNALKSLLPTRECVEVGIGSGRFAAPLGIKMGVEPSKKMAEIARKRGIRVIEG
VAENLPFEDNSLDCILMVTTICFVDDPEKAIKEAYRVLKPGGYIVIGFVDKESLIGREYEKRKDKSVFYRDARFFSAREI
MELLERNGFKIDGVVQTLFKKLDEIRDVEPVEEGYGRGSFVVIRAKKVV

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0638 and MJ1252 and M.tuberculosis Rv2003c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 24134; Mature: 24003

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIEPFEKYTERYEEWFERNKFAYLSELNALKSLLPTRECVEVGIGSGRFAAPLGIKMG
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEECCCCEEEC
VEPSKKMAEIARKRGIRVIEGVAENLPFEDNSLDCILMVTTICFVDDPEKAIKEAYRVLK
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
PGGYIVIGFVDKESLIGREYEKRKDKSVFYRDARFFSAREIMELLERNGFKIDGVVQTLF
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
KKLDEIRDVEPVEEGYGRGSFVVIRAKKVV
HHHHHHCCCCCHHHCCCCCCEEEEEECCCC
>Mature Secondary Structure 
PKIEPFEKYTERYEEWFERNKFAYLSELNALKSLLPTRECVEVGIGSGRFAAPLGIKMG
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEECCCCEEEC
VEPSKKMAEIARKRGIRVIEGVAENLPFEDNSLDCILMVTTICFVDDPEKAIKEAYRVLK
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
PGGYIVIGFVDKESLIGREYEKRKDKSVFYRDARFFSAREIMELLERNGFKIDGVVQTLF
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
KKLDEIRDVEPVEEGYGRGSFVVIRAKKVV
HHHHHHCCCCCHHHCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]