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The map label for this gene is 18977513

Identifier: 18977513

GI number: 18977513

Start: 1095644

End: 1095826

Strand: Direct

Name: 18977513

Synonym: PF1141

Alternate gene names: NA

Gene position: 1095644-1095826 (Clockwise)

Preceding gene: 18977512

Following gene: 18977514

Centisome position: 57.42

GC content: 48.63

Gene sequence:

>183_bases
ATGAGGTTTAGGATAAGGAAGTGTCCCAAGTGTGGGAGATACACCCTCAAGGAAGTCTGCCCTGTGTGTGGGGAAAAGAC
TAAAGTAGCTCATCCACCAAGGTTTTCCCCTGAGGACCCATATGGGGAATATAGGAGAAGGTGGAAGAGGGAGGTACTCG
GAATAGGGAGGAAGGAAAAATGA

Upstream 100 bases:

>100_bases
AAGAAATTCTTAGAGTAATAAAGGAGGCTGGTGGCGAGGCCACACTTCTGAGAAAGGAGAAGAGAATTAGGAAGGTTAAG
AAGAGGAAGAAGTGAGGGTT

Downstream 100 bases:

>100_bases
AGGAAACCACAATTGTTGTATATGAAAGGCCCGATATTTATGACCCAATATTTATTGAGGGCCTTCCTGGGATTGGATTA
GTTGGAAAGCTTGCAGCTGA

Product: H/ACA RNA-protein complex component Nop10p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 60; Mature: 60

Protein sequence:

>60_residues
MRFRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGIGRKEK

Sequences:

>Translated_60_residues
MRFRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGIGRKEK
>Mature_60_residues
MRFRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGIGRKEK

Specific function: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA [H]

COG id: COG2260

COG function: function code J; Predicted Zn-ribbon RNA-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NOP10 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007264 [H]

Pfam domain/function: PF04135 Nop10p [H]

EC number: NA

Molecular weight: Translated: 7224; Mature: 7224

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
6.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGIGRKEK
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRFRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGIGRKEK
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]