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The map label for this gene is idsA [H]

Identifier: 18977474

GI number: 18977474

Start: 1049547

End: 1050569

Strand: Direct

Name: idsA [H]

Synonym: PF1102

Alternate gene names: 18977474

Gene position: 1049547-1050569 (Clockwise)

Preceding gene: 18977473

Following gene: 18977475

Centisome position: 55.0

GC content: 42.72

Gene sequence:

>1023_bases
ATGTATGATGAGCTTTTTAAAAAGATAAAGGAGAAGGCTAAGTTTGTTGATGAAAAACTGCTCTCTCTAATCCCTGAAAA
GGAACCAAAGATTCTTTATGAAGCCGCAAGGCACTATCCCCTGGCTGGTGGAAAAAGGGTTAGGCCATTTGTTGTTTTAA
CGGCAACTGAAGCTGTGGGGGGAGAGTGGGAAAAGGCAATATACCCAGCTGTAGCTATAGAACTAATTCATAATTACTCC
TTAGTGCATGACGATATTATGGATATGGATGAAACTAGGAGGGGAAGGCCCACAGTTCATAAGGTTTGGGGAATCAACAT
GGCAATATTAGCTGGAGATCTGCTCTTCAGCAAGGCCTTTGAGGCTATTTCGAGGGCAGAGATACCACCGGAAAAGAAGG
CAAGAGTTCTTGAAACAGTTGTAAAGGCATCAAATGAGCTTTGTGAAGGTCAAGCTATGGATTTAGAATTTGAGAAGAGG
GACACCGTAACAATAGAAGAGTACATGAGGATGATAAGTGGGAAGACAGGGGCTTTGTTTGATGCATCTGCAAAGGTTGG
AGGAATAGTTGGGACTGACAACGAAGAATACATTAATGCACTATCAACTTGGGGAAGAAACGTTGGAATAGCCTTTCAGA
TTTGGGACGATGTCCTTGACTTGATTGCCGACGAGGAGAAGCTCGGAAAGCCTGTGGGGAGCGATATTAGAAAGGGCAAG
AAAACCCTAATAGTTGCCCACTTCTTCGAAAACGCCGATGAAAAAGATAAGCAGAAGTTCCTGAAAGTTTTCGGAAAGTA
CGCTGGAGATGTAAAGGGGGAGGGGATAATAGAGGAAGACATCAAGGCAGAAGTCATGGAGGCAATAGATTTGCTTAAGA
AATATGGAAGTATAGATTATGCCGCCAACATTGCTAGAGAGATGGTAAAGAAGGCAAATGAAGCCCTTAAGGTTCTTCCT
GAGAGTGAGGCTAGGAAAGATTTAGAACTGCTAGCTAGATTCATTGTTGAAAGGGAGTATTAA

Upstream 100 bases:

>100_bases
CACTATGCAGAATTGGCAGAAGAGGAAGGATATATGATTGGCAAGGATGTTTTCATTTCAAGAAACGGTCATGCAATAAC
AATTTAGGGGGGTGAATTAG

Downstream 100 bases:

>100_bases
CTTTCCTTTTTGCACGTTCCATAAATCTTTTTAAGTCTAAGATTTCTTAAATAAACGATTCTCATGAAGTTTGGAATAGT
TGCAAGGAGGGATAAAGAGG

Product: bifunctional short chain isoprenyl diphosphate synthase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MYDELFKKIKEKAKFVDEKLLSLIPEKEPKILYEAARHYPLAGGKRVRPFVVLTATEAVGGEWEKAIYPAVAIELIHNYS
LVHDDIMDMDETRRGRPTVHKVWGINMAILAGDLLFSKAFEAISRAEIPPEKKARVLETVVKASNELCEGQAMDLEFEKR
DTVTIEEYMRMISGKTGALFDASAKVGGIVGTDNEEYINALSTWGRNVGIAFQIWDDVLDLIADEEKLGKPVGSDIRKGK
KTLIVAHFFENADEKDKQKFLKVFGKYAGDVKGEGIIEEDIKAEVMEAIDLLKKYGSIDYAANIAREMVKKANEALKVLP
ESEARKDLELLARFIVEREY

Sequences:

>Translated_340_residues
MYDELFKKIKEKAKFVDEKLLSLIPEKEPKILYEAARHYPLAGGKRVRPFVVLTATEAVGGEWEKAIYPAVAIELIHNYS
LVHDDIMDMDETRRGRPTVHKVWGINMAILAGDLLFSKAFEAISRAEIPPEKKARVLETVVKASNELCEGQAMDLEFEKR
DTVTIEEYMRMISGKTGALFDASAKVGGIVGTDNEEYINALSTWGRNVGIAFQIWDDVLDLIADEEKLGKPVGSDIRKGK
KTLIVAHFFENADEKDKQKFLKVFGKYAGDVKGEGIIEEDIKAEVMEAIDLLKKYGSIDYAANIAREMVKKANEALKVLP
ESEARKDLELLARFIVEREY
>Mature_340_residues
MYDELFKKIKEKAKFVDEKLLSLIPEKEPKILYEAARHYPLAGGKRVRPFVVLTATEAVGGEWEKAIYPAVAIELIHNYS
LVHDDIMDMDETRRGRPTVHKVWGINMAILAGDLLFSKAFEAISRAEIPPEKKARVLETVVKASNELCEGQAMDLEFEKR
DTVTIEEYMRMISGKTGALFDASAKVGGIVGTDNEEYINALSTWGRNVGIAFQIWDDVLDLIADEEKLGKPVGSDIRKGK
KTLIVAHFFENADEKDKQKFLKVFGKYAGDVKGEGIIEEDIKAEVMEAIDLLKKYGSIDYAANIAREMVKKANEALKVLP
ESEARKDLELLARFIVEREY

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=218, Percent_Identity=32.1100917431193, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI4758430, Length=290, Percent_Identity=26.8965517241379, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI83700220, Length=290, Percent_Identity=26.8965517241379, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789578, Length=297, Percent_Identity=34.3434343434343, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1786623, Length=248, Percent_Identity=34.2741935483871, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17505681, Length=264, Percent_Identity=28.7878787878788, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17508563, Length=246, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319475, Length=311, Percent_Identity=27.9742765273312, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325188, Length=305, Percent_Identity=23.9344262295082, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322294, Length=268, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651612, Length=314, Percent_Identity=26.4331210191083, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281365769, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660002, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137582, Length=206, Percent_Identity=25.2427184466019, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 38305; Mature: 38305

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDELFKKIKEKAKFVDEKLLSLIPEKEPKILYEAARHYPLAGGKRVRPFVVLTATEAVG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHC
GEWEKAIYPAVAIELIHNYSLVHDDIMDMDETRRGRPTVHKVWGINMAILAGDLLFSKAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHH
EAISRAEIPPEKKARVLETVVKASNELCEGQAMDLEFEKRDTVTIEEYMRMISGKTGALF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEHHHHHHHHCCCCCCEE
DASAKVGGIVGTDNEEYINALSTWGRNVGIAFQIWDDVLDLIADEEKLGKPVGSDIRKGK
ECCCCCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHCCC
KTLIVAHFFENADEKDKQKFLKVFGKYAGDVKGEGIIEEDIKAEVMEAIDLLKKYGSIDY
HHEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
AANIAREMVKKANEALKVLPESEARKDLELLARFIVEREY
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYDELFKKIKEKAKFVDEKLLSLIPEKEPKILYEAARHYPLAGGKRVRPFVVLTATEAVG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHC
GEWEKAIYPAVAIELIHNYSLVHDDIMDMDETRRGRPTVHKVWGINMAILAGDLLFSKAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHH
EAISRAEIPPEKKARVLETVVKASNELCEGQAMDLEFEKRDTVTIEEYMRMISGKTGALF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEHHHHHHHHCCCCCCEE
DASAKVGGIVGTDNEEYINALSTWGRNVGIAFQIWDDVLDLIADEEKLGKPVGSDIRKGK
ECCCCCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHCCC
KTLIVAHFFENADEKDKQKFLKVFGKYAGDVKGEGIIEEDIKAEVMEAIDLLKKYGSIDY
HHEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
AANIAREMVKKANEALKVLPESEARKDLELLARFIVEREY
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]