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The map label for this gene is 18977305

Identifier: 18977305

GI number: 18977305

Start: 895395

End: 897290

Strand: Reverse

Name: 18977305

Synonym: PF0933

Alternate gene names: NA

Gene position: 897290-895395 (Counterclockwise)

Preceding gene: 18977317

Following gene: 18977304

Centisome position: 47.02

GC content: 41.88

Gene sequence:

>1896_bases
ATGGAGGAGCTACAGTACTTTCCCTACGAGAGGTTAAGGCCAAATCAGCGAGAATTTATAGAAATTGTGAAAGAAGCTGT
AAAAAGAGGGGAAAACCTTATTGTTGAAGCTCCCACTGGATTTGGAAAAACTATAAGCGTTTTAGCTGGAGTCCTTCCCT
ATGCAATCTCTTTAGGCTATAAAGTTGTGTACCTGGCTAGAACTCATAAGCAGATGGATAGAGTAATAGAGGAGCTCAAA
AAAATTAGGGAAAGGAATGAAGTTAGCGGAATTGAATTCAGGAGTAGAAGGGACTTATGTCTTCACTCCTACATCCAAAC
ATTTGTCCAAGATGCCTACACTAGTATGATAGTCTGTAAAACCCTAAGAAAATTGGGAAAGTGCCCATTCTTTGAAAATA
TAAAAGAGAAAAGAGACAGAGTGGAGGAGATAGTGAGATTTTTCCTGAACTCTCCTCCTTTTCCCCATGAGGTTCTCGAA
TACAGCGAATTACTTGAGCTCTGCCCCTACGAAATTACGAAGAAAATTGGAGAGAAAGCTAATGTTATTGTAGCGAGCTA
CCTGTATATGATAAGCCCTCCAATAAGGCAGGCTTTCTTAGAAAACTTAGGTGTGGATTACTCAGATTTGATAGTTATAT
TTGACGAGGCTCACAACTTACCTGACCAAGCAATTTCTGCACTTAGTGATAGGCTAAGCATAAGGAGCATAGAGAGGGCC
ATTAAGGAGGCCGAAGAGTACGGAGAAAAGGACATTGAGAATTTCCTCTCAATACTCCTAAGGGGATTGGAGATTCTATA
CAAAGAAAAGCTGGAAAATTATGAAAGTGAAGAAGTCCCGATAAGGCCAGAAGAAGTGTTTCTTCACGTAGCTTCCGTTT
TGGGATGGAGTGGAAGGGAAATCGGCATGATGTTGGAAGATATGATTGAAGTTGGAGATGCAATTAGGGAGGATAGAATA
GAGAGAAACCTCCCCCCTAGAAGCTATGTTGGAAGGGTGGGAGAGTTTCTGTGGAATTGGCTTGCCCTTCGAGAGAGGGA
AGATTACCTTCACCTCTTTACAAAAGAGAGAGGACTTGCGTTGGAGTTAGTAGCATTAGATCCCTCAGTAGCCCTCGAAT
TCCTTGAAGAGGTTCACTCTGCAATATTCATGTCCGGAACTCTTAGCCCTTTGGAGGCATTTAGAGATATAATAGGAGTT
AAAGCAGAGTTAAAGAAGTTTCCCAGGATGATAAAGAGAGAAAATGCAATAGTTCTTGTGGCGAGAGACGTGTCTACAAG
GGGGATAGAGAGAAGCCCATCCCTTTATAGAAGAATTTCGGAATACATATTTGAGGCAGTAAGAAATACCCCAAAAAATG
TTGGAGTTTTCACAGCTTCCTATGAAGTTCTTGAAGGAATTCTAAGCACCAATGTCCACATAAAAATTGAAGAAGAGATA
GGGAAAAAGGTCTTTATAGAGAAGAGAGATGCACCGTCAAGAGAGAATGACGAAATGATAAGAGCATTCAAAGAAGAATC
CAAAGGGAAGGGAGCAGTATTATTTGGCGTTATGGGGGGAAGGAACAGTGAAGGGCAAGACTACTCCGGAGATGAAATGA
ACGGTGTTGTCTTAGTTGGGATACCCTATGCAAGGCCCACACCTAGAGTCCAGGCCCAAATTAGATACTTTGAGAAGAAA
TTCCCAGGGAAGGGGAGGTATTATGGGTACGTTTTGCCAGCCCACAGAAAGCTCACCCAAGCTGCGGGGAGAGTTCATAG
GTCTGAAGAGGAGAAGGGAAGCATAGTCATTTTAGACTATAGAGTTTTATGGAAAAGTGTTAAGAAAGATCTTCCTGACT
GGATGGTTGAGACAATGATTCCTGTAACCCTCCCCCACTATGAGAATAAAACTTAG

Upstream 100 bases:

>100_bases
TTCATATGCACACATCTGTGCCCTAACTTATACATTCAGGTATATAGAATATATAGACGGTAGGTTTTTAGGTAGCGAGG
AGACTAGAATTACGAGAAAA

Downstream 100 bases:

>100_bases
GAGATTTTGGAGGGACAGGTTAAATGAAATGGGACAAAAAATGGAATGATGGGATAATATTGGCATTGGAAACAGCTTTT
ATCTCATGGTTTACCTACGC

Product: DNA repair helicase rad3, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MEELQYFPYERLRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGYKVVYLARTHKQMDRVIEELK
KIRERNEVSGIEFRSRRDLCLHSYIQTFVQDAYTSMIVCKTLRKLGKCPFFENIKEKRDRVEEIVRFFLNSPPFPHEVLE
YSELLELCPYEITKKIGEKANVIVASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSIRSIERA
IKEAEEYGEKDIENFLSILLRGLEILYKEKLENYESEEVPIRPEEVFLHVASVLGWSGREIGMMLEDMIEVGDAIREDRI
ERNLPPRSYVGRVGEFLWNWLALREREDYLHLFTKERGLALELVALDPSVALEFLEEVHSAIFMSGTLSPLEAFRDIIGV
KAELKKFPRMIKRENAIVLVARDVSTRGIERSPSLYRRISEYIFEAVRNTPKNVGVFTASYEVLEGILSTNVHIKIEEEI
GKKVFIEKRDAPSRENDEMIRAFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVVLVGIPYARPTPRVQAQIRYFEKK
FPGKGRYYGYVLPAHRKLTQAAGRVHRSEEEKGSIVILDYRVLWKSVKKDLPDWMVETMIPVTLPHYENKT

Sequences:

>Translated_631_residues
MEELQYFPYERLRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGYKVVYLARTHKQMDRVIEELK
KIRERNEVSGIEFRSRRDLCLHSYIQTFVQDAYTSMIVCKTLRKLGKCPFFENIKEKRDRVEEIVRFFLNSPPFPHEVLE
YSELLELCPYEITKKIGEKANVIVASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSIRSIERA
IKEAEEYGEKDIENFLSILLRGLEILYKEKLENYESEEVPIRPEEVFLHVASVLGWSGREIGMMLEDMIEVGDAIREDRI
ERNLPPRSYVGRVGEFLWNWLALREREDYLHLFTKERGLALELVALDPSVALEFLEEVHSAIFMSGTLSPLEAFRDIIGV
KAELKKFPRMIKRENAIVLVARDVSTRGIERSPSLYRRISEYIFEAVRNTPKNVGVFTASYEVLEGILSTNVHIKIEEEI
GKKVFIEKRDAPSRENDEMIRAFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVVLVGIPYARPTPRVQAQIRYFEKK
FPGKGRYYGYVLPAHRKLTQAAGRVHRSEEEKGSIVILDYRVLWKSVKKDLPDWMVETMIPVTLPHYENKT
>Mature_631_residues
MEELQYFPYERLRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGYKVVYLARTHKQMDRVIEELK
KIRERNEVSGIEFRSRRDLCLHSYIQTFVQDAYTSMIVCKTLRKLGKCPFFENIKEKRDRVEEIVRFFLNSPPFPHEVLE
YSELLELCPYEITKKIGEKANVIVASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSIRSIERA
IKEAEEYGEKDIENFLSILLRGLEILYKEKLENYESEEVPIRPEEVFLHVASVLGWSGREIGMMLEDMIEVGDAIREDRI
ERNLPPRSYVGRVGEFLWNWLALREREDYLHLFTKERGLALELVALDPSVALEFLEEVHSAIFMSGTLSPLEAFRDIIGV
KAELKKFPRMIKRENAIVLVARDVSTRGIERSPSLYRRISEYIFEAVRNTPKNVGVFTASYEVLEGILSTNVHIKIEEEI
GKKVFIEKRDAPSRENDEMIRAFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVVLVGIPYARPTPRVQAQIRYFEKK
FPGKGRYYGYVLPAHRKLTQAAGRVHRSEEEKGSIVILDYRVLWKSVKKDLPDWMVETMIPVTLPHYENKT

Specific function: Unknown

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI7706541, Length=742, Percent_Identity=22.911051212938, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI91984775, Length=742, Percent_Identity=23.0458221024259, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI15834617, Length=265, Percent_Identity=26.7924528301887, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI195947407, Length=235, Percent_Identity=26.8085106382979, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI301897118, Length=262, Percent_Identity=24.4274809160305, Blast_Score=77, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994598, Length=540, Percent_Identity=25, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17506821, Length=274, Percent_Identity=25.9124087591241, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554258, Length=273, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507137, Length=266, Percent_Identity=25.187969924812, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321019, Length=713, Percent_Identity=24.9649368863955, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325249, Length=636, Percent_Identity=19.6540880503145, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45551134, Length=275, Percent_Identity=24, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639946, Length=280, Percent_Identity=25.3571428571429, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363902, Length=275, Percent_Identity=24, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17137232, Length=275, Percent_Identity=24, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18543219, Length=279, Percent_Identity=23.6559139784946, Blast_Score=66, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 72852; Mature: 72852

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELQYFPYERLRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGY
CCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
KVVYLARTHKQMDRVIEELKKIRERNEVSGIEFRSRRDLCLHSYIQTFVQDAYTSMIVCK
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLGKCPFFENIKEKRDRVEEIVRFFLNSPPFPHEVLEYSELLELCPYEITKKIGEKA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCC
NVIVASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSIRSIERA
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IKEAEEYGEKDIENFLSILLRGLEILYKEKLENYESEEVPIRPEEVFLHVASVLGWSGRE
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCH
IGMMLEDMIEVGDAIREDRIERNLPPRSYVGRVGEFLWNWLALREREDYLHLFTKERGLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LELVALDPSVALEFLEEVHSAIFMSGTLSPLEAFRDIIGVKAELKKFPRMIKRENAIVLV
EEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
ARDVSTRGIERSPSLYRRISEYIFEAVRNTPKNVGVFTASYEVLEGILSTNVHIKIEEEI
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCEEEEHHHC
GKKVFIEKRDAPSRENDEMIRAFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVVLVG
CCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
IPYARPTPRVQAQIRYFEKKFPGKGRYYGYVLPAHRKLTQAAGRVHRSEEEKGSIVILDY
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEH
RVLWKSVKKDLPDWMVETMIPVTLPHYENKT
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEELQYFPYERLRPNQREFIEIVKEAVKRGENLIVEAPTGFGKTISVLAGVLPYAISLGY
CCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
KVVYLARTHKQMDRVIEELKKIRERNEVSGIEFRSRRDLCLHSYIQTFVQDAYTSMIVCK
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLGKCPFFENIKEKRDRVEEIVRFFLNSPPFPHEVLEYSELLELCPYEITKKIGEKA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCC
NVIVASYLYMISPPIRQAFLENLGVDYSDLIVIFDEAHNLPDQAISALSDRLSIRSIERA
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IKEAEEYGEKDIENFLSILLRGLEILYKEKLENYESEEVPIRPEEVFLHVASVLGWSGRE
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCH
IGMMLEDMIEVGDAIREDRIERNLPPRSYVGRVGEFLWNWLALREREDYLHLFTKERGLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LELVALDPSVALEFLEEVHSAIFMSGTLSPLEAFRDIIGVKAELKKFPRMIKRENAIVLV
EEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
ARDVSTRGIERSPSLYRRISEYIFEAVRNTPKNVGVFTASYEVLEGILSTNVHIKIEEEI
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCEEEEHHHC
GKKVFIEKRDAPSRENDEMIRAFKEESKGKGAVLFGVMGGRNSEGQDYSGDEMNGVVLVG
CCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
IPYARPTPRVQAQIRYFEKKFPGKGRYYGYVLPAHRKLTQAAGRVHRSEEEKGSIVILDY
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEH
RVLWKSVKKDLPDWMVETMIPVTLPHYENKT
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]