Click here to switch to the map view.

The map label for this gene is yngB [H]

Identifier: 18977142

GI number: 18977142

Start: 762368

End: 763246

Strand: Reverse

Name: yngB [H]

Synonym: PF0770

Alternate gene names: 18977142

Gene position: 763246-762368 (Counterclockwise)

Preceding gene: 18977143

Following gene: 18977141

Centisome position: 40.0

GC content: 42.78

Gene sequence:

>879_bases
GTGAAGGTTAGGAAGGCCGTGATTCCAGCTGCTGGCTTGGGAACAAGAATGCTTCCGATAACCAAGTCGATGCCAAAGGA
AATGCTACCAATAGTTGACAGGCCGGCCATTCACTATGTTGTTGAAGAGGCCATTAAAGCCGGAATCGAGGACATCTTGA
TTATCACTGGAAAGGGAAAGAGGGCGATTGAGGATTATTTTGACAGGAGTTTTGAGTTAGAATACTACCTTAGAGAGAGG
GGTAAGTTTGAGGAACTGAAGCAGGTGGAAGAGATTGGAGAGATGGTGGACATCTACTACGTGAGGCAGAAAAAACCCCT
AGGATTGGGAGATGCAATACTACACGCGGAAAAACACGTAAACGGAGAACCCTTCGCAGTCCTACTAGGAGACGACATCA
TAATCAGCAAAAAACCAGCAATCAAACAACTAATGGAAGTTGCAGAGCGAAAGAATACATCCGTAATCGGTGTTGAGAAA
GTACCATGGGAGCTAGTCAGCAGATACGGGATAATAAATGGACAAAAAATCGATGAACAGCTTTACACGATAACAGATAT
GGTAGAGAAACCATCCCCAGACGAAGCACCAAGCAACATGGCAATAATAGGAAGATACGTACTAATTCCTGAAATCTTTG
ATTTCCTTAAAGAAACTCCCCCAGGAAAAGGAGGGGAGATTCAGCTCACGGATGCATTAAGAGCAATGTTAAACGAATAT
GAGATGCTTGCAAAAGTAATTTCGGGGAGAAGATATGATATCGGAACACGCATTGGCTTTATCAAAGCGAACATTGAACT
CAGTTTACTTCGAGATGATCTAAGAGAGGGAGTTATCTTGTTTATAAAAAACATTCTCCAGGAGGTTCAAGATGAGTAG

Upstream 100 bases:

>100_bases
CCGACTTTGAGGAGTTAGATTACTCTGGGAAGATAGTGATCGACGGTAGGAGGATTAAAGCCGCTGAGAGGACTGCAAGA
ATTTATGAGGGGGTGTGCTG

Downstream 100 bases:

>100_bases
ACCTACAGTATCCGTTATAATACCAACCCACAACAGAGCGAAGCTACTAAAGAGAGCCATAATTAGTGTATTAAATCAGA
CATTTGAGGACTTTGAGATA

Product: glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKVRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPAIHYVVEEAIKAGIEDILIITGKGKRAIEDYFDRSFELEYYLRER
GKFEELKQVEEIGEMVDIYYVRQKKPLGLGDAILHAEKHVNGEPFAVLLGDDIIISKKPAIKQLMEVAERKNTSVIGVEK
VPWELVSRYGIINGQKIDEQLYTITDMVEKPSPDEAPSNMAIIGRYVLIPEIFDFLKETPPGKGGEIQLTDALRAMLNEY
EMLAKVISGRRYDIGTRIGFIKANIELSLLRDDLREGVILFIKNILQEVQDE

Sequences:

>Translated_292_residues
MKVRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPAIHYVVEEAIKAGIEDILIITGKGKRAIEDYFDRSFELEYYLRER
GKFEELKQVEEIGEMVDIYYVRQKKPLGLGDAILHAEKHVNGEPFAVLLGDDIIISKKPAIKQLMEVAERKNTSVIGVEK
VPWELVSRYGIINGQKIDEQLYTITDMVEKPSPDEAPSNMAIIGRYVLIPEIFDFLKETPPGKGGEIQLTDALRAMLNEY
EMLAKVISGRRYDIGTRIGFIKANIELSLLRDDLREGVILFIKNILQEVQDE
>Mature_292_residues
MKVRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPAIHYVVEEAIKAGIEDILIITGKGKRAIEDYFDRSFELEYYLRER
GKFEELKQVEEIGEMVDIYYVRQKKPLGLGDAILHAEKHVNGEPFAVLLGDDIIISKKPAIKQLMEVAERKNTSVIGVEK
VPWELVSRYGIINGQKIDEQLYTITDMVEKPSPDEAPSNMAIIGRYVLIPEIFDFLKETPPGKGGEIQLTDALRAMLNEY
EMLAKVISGRRYDIGTRIGFIKANIELSLLRDDLREGVILFIKNILQEVQDE

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=282, Percent_Identity=43.6170212765958, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788355, Length=283, Percent_Identity=40.2826855123675, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790224, Length=263, Percent_Identity=30.0380228136882, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788351, Length=270, Percent_Identity=30.3703703703704, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33098; Mature: 33098

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPAIHYVVEEAIKAGIEDILIITGKGK
CCCCHHHCCCCCCCCEECCCCHHCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
RAIEDYFDRSFELEYYLRERGKFEELKQVEEIGEMVDIYYVRQKKPLGLGDAILHAEKHV
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCC
NGEPFAVLLGDDIIISKKPAIKQLMEVAERKNTSVIGVEKVPWELVSRYGIINGQKIDEQ
CCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCHHHHH
LYTITDMVEKPSPDEAPSNMAIIGRYVLIPEIFDFLKETPPGKGGEIQLTDALRAMLNEY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
EMLAKVISGRRYDIGTRIGFIKANIELSLLRDDLREGVILFIKNILQEVQDE
HHHHHHHCCCCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPAIHYVVEEAIKAGIEDILIITGKGK
CCCCHHHCCCCCCCCEECCCCHHCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
RAIEDYFDRSFELEYYLRERGKFEELKQVEEIGEMVDIYYVRQKKPLGLGDAILHAEKHV
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCC
NGEPFAVLLGDDIIISKKPAIKQLMEVAERKNTSVIGVEKVPWELVSRYGIINGQKIDEQ
CCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCHHHHH
LYTITDMVEKPSPDEAPSNMAIIGRYVLIPEIFDFLKETPPGKGGEIQLTDALRAMLNEY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
EMLAKVISGRRYDIGTRIGFIKANIELSLLRDDLREGVILFIKNILQEVQDE
HHHHHHHCCCCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]