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The map label for this gene is pepQ [H]

Identifier: 18977119

GI number: 18977119

Start: 743892

End: 744968

Strand: Reverse

Name: pepQ [H]

Synonym: PF0747

Alternate gene names: 18977119

Gene position: 744968-743892 (Counterclockwise)

Preceding gene: 18977123

Following gene: 18977117

Centisome position: 39.04

GC content: 40.48

Gene sequence:

>1077_bases
ATGAGAGGAAATCAAAAAATTTTTAGAAAAAGAATGGAGAGATTTCAGGAAGCTTTAAAAGAAAAAGACATAGATGCAGC
AGTTATAAGAACTCTATCAACCTTTATTTACTTAACAGGGACTAAGTGGCTCCGTCCAAGCCTTTTCGTCCCCGCAGAGG
GAGAGCCAACTGTATTCGTTGTTAAAGGAGAAGCGGAAGAATTCAAGAGAAGGAGCTGGATAGAGAATGTAGTTGAATTC
CAAAAAGTTGAAGATCTAATGGCTGGAGTAGTTAAGCTAATTCAAAGTAGTGGAGCTAGAAGGGTAGGGCTTGAGTTTGG
TGTGGAAAGAGACGCATACTTGCTATTTTTCAAAATGTTCCAAAGGCTTAATCCAACTGTCGAAGTAGTGGACATCCTTG
ACATAACTATGGGTATGAGAATGATAAAAGACGAGTGGGAAATAGAAAATATCAGAAAAGCCGCCAAAATAGCTAATAAA
GGAATGAAGGTTGCCGAGGAGATAATCAAGCCAGGACTCAGTGAACTCGAAATAGCGGCAGAAATATACAGAGAGCTTAT
GTTAAATGGAAGTGAGGATCCAAAGGTTTATGTCTCAACTACTCCAAGAGCACACGCCGAACCCTTCCGAGATCTAAAGG
TAAAAGAAAATAGTGTGGTGACGGTTGTTATAGGAACCGACTGGAATCATTATTACGCGAATATGGCAAGAACTTTTGTA
GTAGGGGAGCCTAACGAAAGAGTAAAGAAGGCAATAGAGGTAAAGGAAAAAGCTTTAGAAATTGCCCTAGAAGAAACAAA
AGTAGGCGTCCCACTAAACTCAGTTGAAAGAAAGCTCTTCCAGTTCTTTAAGGAGAACGGATTCGAAGATTCCTACCTCG
CTGGTTACACCCACGGTGTCGGCTTGCTCATAGAAGAACCACCAATGCCCACTATTGTAGTTCCAACGAGAGCAACAAAA
GTTGCAGAAAATATGGTTCTGAGCATAATTCACACACCTCTCATGATTCCAGAAGGGGCAATTAAGCACGAAGATACATA
TCTCGTCAAAAAAGATGAGTTAGAAAAGCTAACCTAA

Upstream 100 bases:

>100_bases
AATCTTTTTTTATCTCCATACTGTCCTTGGGATGTAGTGTTGTTTATCCTTAATAAAATCTATTAAGGAAAGCTATCTAT
AATGATATAGGGGTTAACCA

Downstream 100 bases:

>100_bases
CATTGAATCTAAGAAGAGCATTACGTAAAACCCTAAGAAAAATCCTAATGTCACGAGTTTTTCATTTTCCTCTCTCTTGT
ATATTTCTGGAATCATCTCC

Product: putative proline dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRGNQKIFRKRMERFQEALKEKDIDAAVIRTLSTFIYLTGTKWLRPSLFVPAEGEPTVFVVKGEAEEFKRRSWIENVVEF
QKVEDLMAGVVKLIQSSGARRVGLEFGVERDAYLLFFKMFQRLNPTVEVVDILDITMGMRMIKDEWEIENIRKAAKIANK
GMKVAEEIIKPGLSELEIAAEIYRELMLNGSEDPKVYVSTTPRAHAEPFRDLKVKENSVVTVVIGTDWNHYYANMARTFV
VGEPNERVKKAIEVKEKALEIALEETKVGVPLNSVERKLFQFFKENGFEDSYLAGYTHGVGLLIEEPPMPTIVVPTRATK
VAENMVLSIIHTPLMIPEGAIKHEDTYLVKKDELEKLT

Sequences:

>Translated_358_residues
MRGNQKIFRKRMERFQEALKEKDIDAAVIRTLSTFIYLTGTKWLRPSLFVPAEGEPTVFVVKGEAEEFKRRSWIENVVEF
QKVEDLMAGVVKLIQSSGARRVGLEFGVERDAYLLFFKMFQRLNPTVEVVDILDITMGMRMIKDEWEIENIRKAAKIANK
GMKVAEEIIKPGLSELEIAAEIYRELMLNGSEDPKVYVSTTPRAHAEPFRDLKVKENSVVTVVIGTDWNHYYANMARTFV
VGEPNERVKKAIEVKEKALEIALEETKVGVPLNSVERKLFQFFKENGFEDSYLAGYTHGVGLLIEEPPMPTIVVPTRATK
VAENMVLSIIHTPLMIPEGAIKHEDTYLVKKDELEKLT
>Mature_358_residues
MRGNQKIFRKRMERFQEALKEKDIDAAVIRTLSTFIYLTGTKWLRPSLFVPAEGEPTVFVVKGEAEEFKRRSWIENVVEF
QKVEDLMAGVVKLIQSSGARRVGLEFGVERDAYLLFFKMFQRLNPTVEVVDILDITMGMRMIKDEWEIENIRKAAKIANK
GMKVAEEIIKPGLSELEIAAEIYRELMLNGSEDPKVYVSTTPRAHAEPFRDLKVKENSVVTVVIGTDWNHYYANMARTFV
VGEPNERVKKAIEVKEKALEIALEETKVGVPLNSVERKLFQFFKENGFEDSYLAGYTHGVGLLIEEPPMPTIVVPTRATK
VAENMVLSIIHTPLMIPEGAIKHEDTYLVKKDELEKLT

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 40897; Mature: 40897

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGNQKIFRKRMERFQEALKEKDIDAAVIRTLSTFIYLTGTKWLRPSLFVPAEGEPTVFV
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCCCEEECCCCCCEEEE
VKGEAEEFKRRSWIENVVEFQKVEDLMAGVVKLIQSSGARRVGLEFGVERDAYLLFFKMF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCHHHHHHHHH
QRLNPTVEVVDILDITMGMRMIKDEWEIENIRKAAKIANKGMKVAEEIIKPGLSELEIAA
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EIYRELMLNGSEDPKVYVSTTPRAHAEPFRDLKVKENSVVTVVIGTDWNHYYANMARTFV
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHEEE
VGEPNERVKKAIEVKEKALEIALEETKVGVPLNSVERKLFQFFKENGFEDSYLAGYTHGV
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
GLLIEEPPMPTIVVPTRATKVAENMVLSIIHTPLMIPEGAIKHEDTYLVKKDELEKLT
EEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHCCC
>Mature Secondary Structure
MRGNQKIFRKRMERFQEALKEKDIDAAVIRTLSTFIYLTGTKWLRPSLFVPAEGEPTVFV
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCCCEEECCCCCCEEEE
VKGEAEEFKRRSWIENVVEFQKVEDLMAGVVKLIQSSGARRVGLEFGVERDAYLLFFKMF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCHHHHHHHHH
QRLNPTVEVVDILDITMGMRMIKDEWEIENIRKAAKIANKGMKVAEEIIKPGLSELEIAA
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EIYRELMLNGSEDPKVYVSTTPRAHAEPFRDLKVKENSVVTVVIGTDWNHYYANMARTFV
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHEEE
VGEPNERVKKAIEVKEKALEIALEETKVGVPLNSVERKLFQFFKENGFEDSYLAGYTHGV
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
GLLIEEPPMPTIVVPTRATKVAENMVLSIIHTPLMIPEGAIKHEDTYLVKKDELEKLT
EEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]