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The map label for this gene is gufA [H]

Identifier: 18977118

GI number: 18977118

Start: 743091

End: 743900

Strand: Direct

Name: gufA [H]

Synonym: PF0746

Alternate gene names: 18977118

Gene position: 743091-743900 (Clockwise)

Preceding gene: 18977115

Following gene: 18977120

Centisome position: 38.94

GC content: 40.49

Gene sequence:

>810_bases
ATGTTTGAAAACTTTATCTCAAATCTTGCCTCATACATTCTGAGTATTTCAGGAGGGAACATAATAGTAGTTTCCATATA
TGCTGGACTATTTGTTGCTCTTATGACAACTTTAGGAGCTTTGGTAGCTATAATCGCTCACAAACTTCCTGAGTGGAGCG
TTGATATTAGCCTTTCTTTTGCGGCAGGAGTAATGATTGTAGCTAGTTTTACAAGCCTAATTATCCCAGGAATAGAGCTT
TCAGGTAGATTCCTGCCCGTGGGGGTGGGTATTTTTCTTGGAGTGCTCCTTATATACGCGATTGACAACTTACTTCCCCA
TGAACATTTGGTTAAGGGATATGAGGGCCCTAGAGAACTTAAAGAAAGATTAAGAACAGTGTGGTTAATTGTGTTTGCTG
TTATAATTCATAATTTGCCCGAGGGTTTAGCCATAGGAACGTCTCTTGTGTACAATCTTAAGAGTGGTCTTGTTACTGCA
ATAGCAATTGGAATACAGGATTTCCCTGAAGGAACAGTTGTTTCTCTCCCCCTGGCTTCTATTCAAAAGAAGCGTCTAAC
TCCTATAGCAATGGGAGCTTTGAGCGGTATAGCTGAGATGATAATGGTGGTCTTGGGGGCATTGCTTTTCTCTTTCTTCC
ATGGCCTTCTTCCCTATGGGTTAGGATTGGCTGGAGGGGCAATGCTTTATGTTACCGTGAAGGAGATGATTCCAGAAATA
TACAAGAGAGAGGAAAATGAAAAACTCGTGACATTAGGATTTTTCTTAGGGTTTTACGTAATGCTCTTCTTAGATTCAAT
GTTAGGTTAG

Upstream 100 bases:

>100_bases
CCTCCATAAAAGAGTAAAAAGTCTTTTAGAACTTCCATGAGTATCACCCTTTTCAGTAACCTTTTAAGTTTAAAATTCTT
TTTTCTCCTGGGGATGACAG

Downstream 100 bases:

>100_bases
CTTTTCTAACTCATCTTTTTTGACGAGATATGTATCTTCGTGCTTAATTGCCCCTTCTGGAATCATGAGAGGTGTGTGAA
TTATGCTCAGAACCATATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MFENFISNLASYILSISGGNIIVVSIYAGLFVALMTTLGALVAIIAHKLPEWSVDISLSFAAGVMIVASFTSLIIPGIEL
SGRFLPVGVGIFLGVLLIYAIDNLLPHEHLVKGYEGPRELKERLRTVWLIVFAVIIHNLPEGLAIGTSLVYNLKSGLVTA
IAIGIQDFPEGTVVSLPLASIQKKRLTPIAMGALSGIAEMIMVVLGALLFSFFHGLLPYGLGLAGGAMLYVTVKEMIPEI
YKREENEKLVTLGFFLGFYVMLFLDSMLG

Sequences:

>Translated_269_residues
MFENFISNLASYILSISGGNIIVVSIYAGLFVALMTTLGALVAIIAHKLPEWSVDISLSFAAGVMIVASFTSLIIPGIEL
SGRFLPVGVGIFLGVLLIYAIDNLLPHEHLVKGYEGPRELKERLRTVWLIVFAVIIHNLPEGLAIGTSLVYNLKSGLVTA
IAIGIQDFPEGTVVSLPLASIQKKRLTPIAMGALSGIAEMIMVVLGALLFSFFHGLLPYGLGLAGGAMLYVTVKEMIPEI
YKREENEKLVTLGFFLGFYVMLFLDSMLG
>Mature_269_residues
MFENFISNLASYILSISGGNIIVVSIYAGLFVALMTTLGALVAIIAHKLPEWSVDISLSFAAGVMIVASFTSLIIPGIEL
SGRFLPVGVGIFLGVLLIYAIDNLLPHEHLVKGYEGPRELKERLRTVWLIVFAVIIHNLPEGLAIGTSLVYNLKSGLVTA
IAIGIQDFPEGTVVSLPLASIQKKRLTPIAMGALSGIAEMIMVVLGALLFSFFHGLLPYGLGLAGGAMLYVTVKEMIPEI
YKREENEKLVTLGFFLGFYVMLFLDSMLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=152, Percent_Identity=40.7894736842105, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI229577422, Length=152, Percent_Identity=40.7894736842105, Blast_Score=95, Evalue=7e-20,
Organism=Escherichia coli, GI1789419, Length=236, Percent_Identity=27.5423728813559, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507805, Length=321, Percent_Identity=34.5794392523364, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24652846, Length=167, Percent_Identity=37.7245508982036, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29018; Mature: 29018

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENFISNLASYILSISGGNIIVVSIYAGLFVALMTTLGALVAIIAHKLPEWSVDISLSF
CHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
AAGVMIVASFTSLIIPGIELSGRFLPVGVGIFLGVLLIYAIDNLLPHEHLVKGYEGPREL
HHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHH
KERLRTVWLIVFAVIIHNLPEGLAIGTSLVYNLKSGLVTAIAIGIQDFPEGTVVSLPLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHH
IQKKRLTPIAMGALSGIAEMIMVVLGALLFSFFHGLLPYGLGLAGGAMLYVTVKEMIPEI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YKREENEKLVTLGFFLGFYVMLFLDSMLG
HCCCCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFENFISNLASYILSISGGNIIVVSIYAGLFVALMTTLGALVAIIAHKLPEWSVDISLSF
CHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
AAGVMIVASFTSLIIPGIELSGRFLPVGVGIFLGVLLIYAIDNLLPHEHLVKGYEGPREL
HHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHH
KERLRTVWLIVFAVIIHNLPEGLAIGTSLVYNLKSGLVTAIAIGIQDFPEGTVVSLPLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHH
IQKKRLTPIAMGALSGIAEMIMVVLGALLFSFFHGLLPYGLGLAGGAMLYVTVKEMIPEI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YKREENEKLVTLGFFLGFYVMLFLDSMLG
HCCCCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]