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The map label for this gene is pmtA [H]

Identifier: 18977110

GI number: 18977110

Start: 733362

End: 733907

Strand: Reverse

Name: pmtA [H]

Synonym: PF0738

Alternate gene names: 18977110

Gene position: 733907-733362 (Counterclockwise)

Preceding gene: 18977111

Following gene: 18977108

Centisome position: 38.46

GC content: 44.69

Gene sequence:

>546_bases
ATGGAGATACGAGCTTTTTCAAAATACAGGAAAAGAGCCCTAAGTCTTGTTAGGGGTAAAGTCCTCGAGATAGGAGTAGG
AACGGGAAAGAACCTCCCATATTACCCGAAGGATGTGGAGGTTATTGGCATAGACTTCAGCAGAAACATGCTTAAAAAAG
CTGAAGAACGGAGAAGGAAGCTCAGGTTAGAGAACGTCACGCTTTTATACATGGACGCCCAAGATCTGGAGTTTGAGGAT
AATACCTTCGACACCATAGTTAGCACGTTCGTCTTCTGTACAGTTCCAGATCCGATTAAAGGGCTAAAAGAGGCTTACAG
AGTGCTAAAACCTGGAGGAAGAGCAATATTTCTTGAGCACATGAAAAGCGAGTCAAAGCTTCTCAACGTCCCCCTCTACC
TCATGGAGCCCTTCATAAGAACGCTCCTCGGAACTTCTCTGCTGAGGGAAACTCAGAGAAACATCGAGAGGGCGGGCTTT
AAAATAGAAAAGGTCGAGAACCTCTTCTATGATATCGTGAGGCTGATAATAGCTACAAAAGACTGA

Upstream 100 bases:

>100_bases
TAATTTGGAAGTTTGCAAGGATAATTAACAGGCGAGAACCGTGAACCCCGCGAAAAAATATGATAGATTTGCAAAGATTT
ATGATCTGTTTGAAAGCCCT

Downstream 100 bases:

>100_bases
GGATTGAGCTGTTAATCCTCACCCTTCAAGAAGCTTTCTCTTTCTTCTCTGATATTCCTCGTCGTCTATCTCGCCTCTGG
CGTATTTTTCATCGAGAATT

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MEIRAFSKYRKRALSLVRGKVLEIGVGTGKNLPYYPKDVEVIGIDFSRNMLKKAEERRRKLRLENVTLLYMDAQDLEFED
NTFDTIVSTFVFCTVPDPIKGLKEAYRVLKPGGRAIFLEHMKSESKLLNVPLYLMEPFIRTLLGTSLLRETQRNIERAGF
KIEKVENLFYDIVRLIIATKD

Sequences:

>Translated_181_residues
MEIRAFSKYRKRALSLVRGKVLEIGVGTGKNLPYYPKDVEVIGIDFSRNMLKKAEERRRKLRLENVTLLYMDAQDLEFED
NTFDTIVSTFVFCTVPDPIKGLKEAYRVLKPGGRAIFLEHMKSESKLLNVPLYLMEPFIRTLLGTSLLRETQRNIERAGF
KIEKVENLFYDIVRLIIATKD
>Mature_181_residues
MEIRAFSKYRKRALSLVRGKVLEIGVGTGKNLPYYPKDVEVIGIDFSRNMLKKAEERRRKLRLENVTLLYMDAQDLEFED
NTFDTIVSTFVFCTVPDPIKGLKEAYRVLKPGGRAIFLEHMKSESKLLNVPLYLMEPFIRTLLGTSLLRETQRNIERAGF
KIEKVENLFYDIVRLIIATKD

Specific function: This enzyme catalyzes three distinct methylation reactions for converting phosphatidylethanolamine to phosphatidylcholine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI89145417, Length=164, Percent_Identity=31.7073170731707, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI164663805, Length=157, Percent_Identity=32.484076433121, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI48994983, Length=111, Percent_Identity=38.7387387387387, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.17 [H]

Molecular weight: Translated: 21037; Mature: 21037

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAFSKYRKRALSLVRGKVLEIGVGTGKNLPYYPKDVEVIGIDFSRNMLKKAEERRRK
CCCHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
LRLENVTLLYMDAQDLEFEDNTFDTIVSTFVFCTVPDPIKGLKEAYRVLKPGGRAIFLEH
HHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEHHHH
MKSESKLLNVPLYLMEPFIRTLLGTSLLRETQRNIERAGFKIEKVENLFYDIVRLIIATK
HCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MEIRAFSKYRKRALSLVRGKVLEIGVGTGKNLPYYPKDVEVIGIDFSRNMLKKAEERRRK
CCCHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
LRLENVTLLYMDAQDLEFEDNTFDTIVSTFVFCTVPDPIKGLKEAYRVLKPGGRAIFLEH
HHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEHHHH
MKSESKLLNVPLYLMEPFIRTLLGTSLLRETQRNIERAGFKIEKVENLFYDIVRLIIATK
HCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8340421 [H]