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The map label for this gene is ahpC [H]

Identifier: 18977094

GI number: 18977094

Start: 720416

End: 720985

Strand: Direct

Name: ahpC [H]

Synonym: PF0722

Alternate gene names: 18977094

Gene position: 720416-720985 (Clockwise)

Preceding gene: 18977092

Following gene: 18977095

Centisome position: 37.75

GC content: 45.61

Gene sequence:

>570_bases
ATGATAAGGGTTGGAGAAGTGGTTCCTGATTTCGAGGCCGATGCTTACTTTCCGGAGAAGGACGAAATAGGAAAGCTCAG
GATTTCGGACTACAGAGGCAAATGGGTCGTTCTGGCCTTTTATCCAGCGGACTTTACGTTTGTCTGCCCAACGGAGCTTG
AGGAGCTCGCTGAGTATTATGAGGAATTCAAGAAGGAAGGAGCTGAAATAATAAGCGTTTCAACGGACACAGCTTATGTT
CACAAAGCTTGGCATGATACTTCACCCGCTATAAAGAAAGTGAGATTTCCGATGCTTGCTGATCCTGCTGGAAAGATATG
TAGGCTCTTTGGAACATACATTGAAGATGAGGGCATCTCCTGGAGAGCTACCTTCATAATAGATCCTGATGGAAAAGTTG
TTCACATGGAAATGCACGACAACAGCATAGGTAGAAGTGCTAAAGAGATACTCAGAAGGCTTAGGGCCGCTAAATTCGTT
CGCGAGAATCCTGGAGTGGTCTGTCCAGCAAGCTGGGAACCTGGCAAGGAAGCCTTAAAAGTTAGCCTTGATCTTGTTGG
GAAAATATGA

Upstream 100 bases:

>100_bases
TATCCTCTCGAAATGAAAAGTTTCGAAATTAAAAACTTTACACTTTGTTAGGACAACCTTTTTAAATTAGGGGAACCTAA
TTAATGATGGGGTAAACCAA

Downstream 100 bases:

>100_bases
TTTTCTTTTCTTATTTCTCTTTATCGCAAAGATGTGTACTTCCAAAGGAAAAACTATTTTGGAGCTAATTTTTAGATCTT
GTAAAACGATTTTCCTCCCA

Product: alkyl hydroperoxide reductase subunit c

Products: NA

Alternate protein names: Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MIRVGEVVPDFEADAYFPEKDEIGKLRISDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEIISVSTDTAYV
HKAWHDTSPAIKKVRFPMLADPAGKICRLFGTYIEDEGISWRATFIIDPDGKVVHMEMHDNSIGRSAKEILRRLRAAKFV
RENPGVVCPASWEPGKEALKVSLDLVGKI

Sequences:

>Translated_189_residues
MIRVGEVVPDFEADAYFPEKDEIGKLRISDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEIISVSTDTAYV
HKAWHDTSPAIKKVRFPMLADPAGKICRLFGTYIEDEGISWRATFIIDPDGKVVHMEMHDNSIGRSAKEILRRLRAAKFV
RENPGVVCPASWEPGKEALKVSLDLVGKI
>Mature_189_residues
MIRVGEVVPDFEADAYFPEKDEIGKLRISDYRGKWVVLAFYPADFTFVCPTELEELAEYYEEFKKEGAEIISVSTDTAYV
HKAWHDTSPAIKKVRFPMLADPAGKICRLFGTYIEDEGISWRATFIIDPDGKVVHMEMHDNSIGRSAKEILRRLRAAKFV
RENPGVVCPASWEPGKEALKVSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=185, Percent_Identity=39.4594594594595, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI4505591, Length=181, Percent_Identity=39.2265193370166, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI32455266, Length=181, Percent_Identity=39.2265193370166, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI32455264, Length=181, Percent_Identity=39.2265193370166, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI5453549, Length=161, Percent_Identity=39.1304347826087, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=36.8131868131868, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI32483377, Length=164, Percent_Identity=38.4146341463415, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI33188454, Length=87, Percent_Identity=44.8275862068966, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1786822, Length=160, Percent_Identity=50.625, Blast_Score=183, Evalue=5e-48,
Organism=Escherichia coli, GI1788825, Length=142, Percent_Identity=26.7605633802817, Blast_Score=60, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193204376, Length=180, Percent_Identity=40.5555555555556, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=180, Percent_Identity=40.5555555555556, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17554494, Length=154, Percent_Identity=41.5584415584416, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323613, Length=163, Percent_Identity=36.8098159509202, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320661, Length=159, Percent_Identity=37.7358490566038, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319407, Length=191, Percent_Identity=29.8429319371728, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=38.2198952879581, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI17738015, Length=187, Percent_Identity=37.4331550802139, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24656348, Length=179, Percent_Identity=40.2234636871508, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17864676, Length=179, Percent_Identity=40.2234636871508, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17157991, Length=157, Percent_Identity=40.1273885350318, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641739, Length=157, Percent_Identity=40.1273885350318, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652434, Length=190, Percent_Identity=32.6315789473684, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24652436, Length=190, Percent_Identity=32.6315789473684, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17975518, Length=190, Percent_Identity=32.6315789473684, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581278, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21446; Mature: 21446

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVGEVVPDFEADAYFPEKDEIGKLRISDYRGKWVVLAFYPADFTFVCPTELEELAEYY
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCEEEECHHHHHHHHHHH
EEFKKEGAEIISVSTDTAYVHKAWHDTSPAIKKVRFPMLADPAGKICRLFGTYIEDEGIS
HHHHHCCCEEEEEECCCCEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
WRATFIIDPDGKVVHMEMHDNSIGRSAKEILRRLRAAKFVRENPGVVCPASWEPGKEALK
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHE
VSLDLVGKI
EHEEEECCC
>Mature Secondary Structure
MIRVGEVVPDFEADAYFPEKDEIGKLRISDYRGKWVVLAFYPADFTFVCPTELEELAEYY
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCEEEECHHHHHHHHHHH
EEFKKEGAEIISVSTDTAYVHKAWHDTSPAIKKVRFPMLADPAGKICRLFGTYIEDEGIS
HHHHHCCCEEEEEECCCCEEEHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
WRATFIIDPDGKVVHMEMHDNSIGRSAKEILRRLRAAKFVRENPGVVCPASWEPGKEALK
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHE
VSLDLVGKI
EHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA