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The map label for this gene is yeeO [C]

Identifier: 18977080

GI number: 18977080

Start: 711275

End: 712660

Strand: Reverse

Name: yeeO [C]

Synonym: PF0708

Alternate gene names: 18977080

Gene position: 712660-711275 (Counterclockwise)

Preceding gene: 18977081

Following gene: 33359500

Centisome position: 37.35

GC content: 55.12

Gene sequence:

>1386_bases
ATGAGTGAAAAAACCACCAAGGGCGTCCAGCTTTTGAGGGGCGACCCCAAAAAGGCCATAGTCAGGCTCTCGATTCCCAT
GATGATAGGCATGTCGGTTCAGACCCTATACAACCTCGCCGATGGAATATGGGTCTCGGGCCTAGGCCCGGAATCGCTTG
CGGCTGTCGGCCTCTTCTTCCCGGTCTTCATGGGCATAATAGCGCTCGCTGCCGGCCTGGGAGTGGGCACGAGCTCCGCG
ATAGCGAGAAGGATAGGCGCGAGGGACAAGGAAGGAGCTGACAACGTTGCCGTCCATTCCCTCATCCTCTCCCTCATCCT
TGGAGTTACGATAACTATCACAATGCTCCCGGCTATAGATTCCCTCTTCCGCTCCATGGGCGCAAAAGGAGAAGCCGTCG
AGCTGGCCATAGAGTATGCTAGGGTTCTCCTTGCCGGGGCGTTCATCATAGTCTTCAACAACGTCGGCAACGGCATCCTT
AGGGGAGAGGGAGACGCCAACAGGGCCATGTTAGCTATGGTGCTCGGCTCGGGCCTCAACATAGTCCTTGACCCGATATT
TATCTACACCCTCGGCTTTGGCGTCGTCGGAGCGGCCTACGCGACGCTGCTCTCCATGGTGGTGACCTCTCTCTTCATCG
CCTACTGGCTCTTCGTAAAACGGGACACCTACGTGGACATAACCCTTAGAGACTTCTCACCGAGTAGGGAGATCCTAAAG
GACATCCTCCGGGTTGGCCTGCCTTCCTCGCTCTCCCAGCTCTCGATGTCCATAGCGATGTTCTTCCTCAACAGCGTCGC
CATAACTGCTGGAGGGGAGAACGGAGTTGCAGTCTTCACGAGCGCGTGGAGAATCACGATGCTCGGCATAGTTCCAATAC
TCGGAATGGCGGCCGCGACCACATCCGTCACTGGAGCGGCCTACGGGGAGAGAAACGTAGAGAAGCTTGAAACTGCCTAT
CTCTATGCCATCAAGATCGCCTTCATGATAGAGCTTGCCGTTGTTGCATTCATAATGCTCTTCGCGCCCCAGGTGGCATA
CCTCTTCACGTACTCGGAATCTGCCCAGGTGATAAAGGGAGATCTCATAAGCGCTCTAAGAACCCTCCCGGTCTTTCTCG
TCCTCACGCCCTTCGGAATGATGACTTCGGCGATGTTCCAGGGCATAGGGGAGGGCGAGAAGTCCCTAATCCTCACAATA
TTCAGGACGCTAGTGATGCAGGTAGGCTTTGCCTACATCTTCGTCCACTACACGACCCTGGGCCTCAGGGGAGTGTGGAT
TGGAATAGTAATTGGAAACATGGTTGCTGCTATCGTTGGATTCCTGTGGGGTCGGATGAGGATAAGCGCTTTGAAGAAAA
CCTCCGCTACAGGGGGTAAAAGGTAA

Upstream 100 bases:

>100_bases
AAAGGAGCTTGATGAAAAGATTTTCGCCGAAATGAGTGTAGATGAAAGGATTGTTTTGTAAAGCTACTGAGAAAGGCCAT
AAAAGGACTGGGGGAGAAGA

Downstream 100 bases:

>100_bases
AGGGAAGGGGCTTACCCCCCTTCTCCTCGCTATTATGTCTGAGAGAAGCTCGCCATCGTAGCCAACGTTTTCCGTCTCGT
TCTCATGGATTATGACGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSEKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSA
IARRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGIL
RGEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATLLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILK
DILRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSVTGAAYGERNVEKLETAY
LYAIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKGDLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTI
FRTLVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKTSATGGKR

Sequences:

>Translated_461_residues
MSEKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSA
IARRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGIL
RGEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATLLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILK
DILRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSVTGAAYGERNVEKLETAY
LYAIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKGDLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTI
FRTLVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKTSATGGKR
>Mature_460_residues
SEKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSAI
ARRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILR
GEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATLLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKD
ILRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSVTGAAYGERNVEKLETAYL
YAIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKGDLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIF
RTLVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKTSATGGKR

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=434, Percent_Identity=22.1198156682028, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48994890, Length=447, Percent_Identity=23.7136465324385, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49239; Mature: 49108

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLAAVGLFF
CCCCCHHHHHHHCCCCHHEEEEEECHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
PVFMGIIALAAGLGVGTSSAIARRIGARDKEGADNVAVHSLILSLILGVTITITMLPAID
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRGEGDANRAMLAMVLGSGLN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHHHHHHHHCCCCH
IVLDPIFIYTLGFGVVGAAYATLLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
DILRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAAT
HHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
TSVTGAAYGERNVEKLETAYLYAIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHH
DLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRTLVMQVGFAYIFVHYTTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKTSATGGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLAAVGLFF
CCCCHHHHHHHCCCCHHEEEEEECHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
PVFMGIIALAAGLGVGTSSAIARRIGARDKEGADNVAVHSLILSLILGVTITITMLPAID
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRGEGDANRAMLAMVLGSGLN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHHHHHHHHCCCCH
IVLDPIFIYTLGFGVVGAAYATLLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
DILRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAAT
HHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
TSVTGAAYGERNVEKLETAYLYAIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHH
DLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRTLVMQVGFAYIFVHYTTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKTSATGGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]