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The map label for this gene is cfiA [H]

Identifier: 18977045

GI number: 18977045

Start: 683759

End: 684193

Strand: Direct

Name: cfiA [H]

Synonym: PF0673

Alternate gene names: 18977045

Gene position: 683759-684193 (Clockwise)

Preceding gene: 18977044

Following gene: 18977046

Centisome position: 35.83

GC content: 45.75

Gene sequence:

>435_bases
ATGAAGGTCAAGATCGTTATAAATGGAGAGGAATACGAGGTTGAAGTAGAGGAAATAATGCCTGGAAAGTTCAAGGTTAC
TCTGGAAGGAGAAACTTACGAAGTGGAAGCCAAAGACCTGGGAATCTCTACCCCAGCTCCAGTTCCACAAGTTCCCACTC
CAACCCCAGCTCCAGCCCCTGCCCCAATGCCAACTTCAACACCAGCTTCACCACAAGTCGGGGATAACGTGGTTACAGCT
CCAATGCCTGGAAAAATACTGAAGATACTTGTAAGCGAAGGGCAAAGGGTAACAATAGGTCAAGGATTACTAATTCTGGA
AGCAATGAAGATGGAGAACGAAATTCCATCGCCTAAGGATGGCGTTGTGAAGAAGATTTACGTCAAAGAAGGAGACACAG
TTGATACTGGACAGCCATTAATTGAGTTAGGGTGA

Upstream 100 bases:

>100_bases
CAATCAAGAGAAAACCTTCTCCAAATTGGTGGTTATCTGGTCTCATCACCCAAATGGAAGAAGTTGAAAACTTCAACTAT
GAGATAGGGAAGTGGTGAGG

Downstream 100 bases:

>100_bases
GGGAGAATGGGACTTGAACAGGCAGTAGTTGACTTCTTCAACCACATGGGACTTCTTAATTTAACAGTGGGAAATGTAGT
GATGATCATAGTTGGATTAA

Product: putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit

Products: NA

Alternate protein names: 2-oxoglutarate carboxylase alpha subunit [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKVKIVINGEEYEVEVEEIMPGKFKVTLEGETYEVEAKDLGISTPAPVPQVPTPTPAPAPAPMPTSTPASPQVGDNVVTA
PMPGKILKILVSEGQRVTIGQGLLILEAMKMENEIPSPKDGVVKKIYVKEGDTVDTGQPLIELG

Sequences:

>Translated_144_residues
MKVKIVINGEEYEVEVEEIMPGKFKVTLEGETYEVEAKDLGISTPAPVPQVPTPTPAPAPAPMPTSTPASPQVGDNVVTA
PMPGKILKILVSEGQRVTIGQGLLILEAMKMENEIPSPKDGVVKKIYVKEGDTVDTGQPLIELG
>Mature_144_residues
MKVKIVINGEEYEVEVEEIMPGKFKVTLEGETYEVEAKDLGISTPAPVPQVPTPTPAPAPAPMPTSTPASPQVGDNVVTA
PMPGKILKILVSEGQRVTIGQGLLILEAMKMENEIPSPKDGVVKKIYVKEGDTVDTGQPLIELG

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=64, Percent_Identity=46.875, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1789653, Length=104, Percent_Identity=37.5, Blast_Score=67, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71987519, Length=149, Percent_Identity=33.5570469798658, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.7 [H]

Molecular weight: Translated: 15315; Mature: 15315

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKIVINGEEYEVEVEEIMPGKFKVTLEGETYEVEAKDLGISTPAPVPQVPTPTPAPAP
CEEEEEECCCCEEEEHHHCCCCEEEEEECCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
APMPTSTPASPQVGDNVVTAPMPGKILKILVSEGQRVTIGQGLLILEAMKMENEIPSPKD
CCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCCEEEECCCEEEEEEHHHHCCCCCCCC
GVVKKIYVKEGDTVDTGQPLIELG
CCEEEEEEECCCCCCCCCCEEECC
>Mature Secondary Structure
MKVKIVINGEEYEVEVEEIMPGKFKVTLEGETYEVEAKDLGISTPAPVPQVPTPTPAPAP
CEEEEEECCCCEEEEHHHCCCCEEEEEECCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
APMPTSTPASPQVGDNVVTAPMPGKILKILVSEGQRVTIGQGLLILEAMKMENEIPSPKD
CCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCCEEEECCCEEEEEEHHHHCCCCCCCC
GVVKKIYVKEGDTVDTGQPLIELG
CCEEEEEEECCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA