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The map label for this gene is xanB [H]

Identifier: 18976961

GI number: 18976961

Start: 608213

End: 609598

Strand: Reverse

Name: xanB [H]

Synonym: PF0589

Alternate gene names: 18976961

Gene position: 609598-608213 (Counterclockwise)

Preceding gene: 33359488

Following gene: 18976960

Centisome position: 31.95

GC content: 43.51

Gene sequence:

>1386_bases
ATGAAGACATTAATTCTTGCTGGAGGAAAGGGAACGAGGCTTTGGCCACTGAGCAGAGAGCTAATGCCAAAGCAATTCAT
AAAAGTTTTCTCAAATAAATCTCTTTTCCAGAAAACAGTTGAGAGAGCACTAATTTTCTCAAAACCAAAGGAGATTTTCG
TTGTTACCAACAAAGAATACAGGTTCAGGGTTCTTGACGACTTAAACGAAATTGGAGTTAATATTCCAGAAGAGAACATC
CTTTTGGAACCCGTTGGGAAAAATACACTACCCGCAATTTATTGGGGACTCAAAGTTATCGACGAAAGCTTTGGAGACTC
AATAGTTGCAGTGCTACCAAGTGACCATGCGATAGATGTTAACGAGAACTACATAGAGGCCTTCAAGAAGGCTGAGAAGC
TCGCTGAAAATTACCTGGTTACCTTTGGAATAAAGCCAACGAAGCCACACACAGGTTATGGCTACATAAAGCCAGGAGAG
AAGATAAGCAACTTAGGATTTCTAGTTGATGAGTTTAAGGAAAAGCCAGACTTGGAAACCGCTAAAAGATACGTAGAGAA
CGGTTACTACTGGAACAGTGGAATGTTCATGTTCAGGACAACCCTCTTTATGGAAGAGGCCAGAAAGCATGCTCCAGATG
TAGTAAAGGCCTTTGAAGAAGGGAAGACTATAGAGGAAGCCTACGAATTAGCCCCAGAGATAAGCGTTGACTATGGAATC
ATGGAGAAGACCGATAAAGCGGCGGTTGTTCCGCTAAACACATACTGGAACGACCTGGGAAGCTTCGATGCCGTATATGA
GGCACTTCAAAAGGACGAGAATGGTAACGCTGTGGAGGTAAGGGGATTCAAGGCGAAGTACATAAACGTCGACTCCAAGA
ACAACCTAATTCTAACTGAAAGGTTAACAGCAACCGTTGGGGTTGAGGATCTAATTATTGTTGATACGGGAGATGCACTC
TTAGTTGCAAAGAAAGGAGAAACTCAGAAGGTCAAAGAGGTTTACAAGAAACTCAAGGAAGAAAACGATGAGAGGGCAAT
AGTTCATAGGACAGCTTATAGGCCATGGGGAAGCTACACAGTTCTGGAAGAAGGAGAGAGGTACAAGATAAAGAGGATAA
CCGTTCTACCTGGGAAAAGGCTAAGCCTACAACTCCACTACCACAGGAGCGAGCACTGGGTAGTTGTCAGGGGAACTGCA
AAGGTTAGGGTTGGTGACAAGGAATTCATTCTAAGGCCAGGAGAAAGCACATTCATCCCAGCGGGTGTTATCCATAGACT
AGAAAACCCAGGAAAAGTGGTTTTAGAAGTAATTGAGACTCAGATAGGAGAGTATCTTGGAGAGGACGACATAGTTAGAA
TAGAGGACGACTACCAGAGGGCTTAG

Upstream 100 bases:

>100_bases
GTCGATTTTGCATTTCTCATTGGAGATTTAAGACATGAAAATGCTGAAAATGTTACATCCATTAAAGATGTGTTAAAGAA
AATTTAAAGGAGGTGATGAC

Downstream 100 bases:

>100_bases
GTTTTTAACTTCTTTTTTATTAATCACTGGAGGTGATAAAATGGGGAAGCTGTTTGGAACATTTGGAGTGAGGGGGACAG
CAAACAAGGACATAACCCCA

Product: mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKTLILAGGKGTRLWPLSRELMPKQFIKVFSNKSLFQKTVERALIFSKPKEIFVVTNKEYRFRVLDDLNEIGVNIPEENI
LLEPVGKNTLPAIYWGLKVIDESFGDSIVAVLPSDHAIDVNENYIEAFKKAEKLAENYLVTFGIKPTKPHTGYGYIKPGE
KISNLGFLVDEFKEKPDLETAKRYVENGYYWNSGMFMFRTTLFMEEARKHAPDVVKAFEEGKTIEEAYELAPEISVDYGI
MEKTDKAAVVPLNTYWNDLGSFDAVYEALQKDENGNAVEVRGFKAKYINVDSKNNLILTERLTATVGVEDLIIVDTGDAL
LVAKKGETQKVKEVYKKLKEENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQLHYHRSEHWVVVRGTA
KVRVGDKEFILRPGESTFIPAGVIHRLENPGKVVLEVIETQIGEYLGEDDIVRIEDDYQRA

Sequences:

>Translated_461_residues
MKTLILAGGKGTRLWPLSRELMPKQFIKVFSNKSLFQKTVERALIFSKPKEIFVVTNKEYRFRVLDDLNEIGVNIPEENI
LLEPVGKNTLPAIYWGLKVIDESFGDSIVAVLPSDHAIDVNENYIEAFKKAEKLAENYLVTFGIKPTKPHTGYGYIKPGE
KISNLGFLVDEFKEKPDLETAKRYVENGYYWNSGMFMFRTTLFMEEARKHAPDVVKAFEEGKTIEEAYELAPEISVDYGI
MEKTDKAAVVPLNTYWNDLGSFDAVYEALQKDENGNAVEVRGFKAKYINVDSKNNLILTERLTATVGVEDLIIVDTGDAL
LVAKKGETQKVKEVYKKLKEENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQLHYHRSEHWVVVRGTA
KVRVGDKEFILRPGESTFIPAGVIHRLENPGKVVLEVIETQIGEYLGEDDIVRIEDDYQRA
>Mature_461_residues
MKTLILAGGKGTRLWPLSRELMPKQFIKVFSNKSLFQKTVERALIFSKPKEIFVVTNKEYRFRVLDDLNEIGVNIPEENI
LLEPVGKNTLPAIYWGLKVIDESFGDSIVAVLPSDHAIDVNENYIEAFKKAEKLAENYLVTFGIKPTKPHTGYGYIKPGE
KISNLGFLVDEFKEKPDLETAKRYVENGYYWNSGMFMFRTTLFMEEARKHAPDVVKAFEEGKTIEEAYELAPEISVDYGI
MEKTDKAAVVPLNTYWNDLGSFDAVYEALQKDENGNAVEVRGFKAKYINVDSKNNLILTERLTATVGVEDLIIVDTGDAL
LVAKKGETQKVKEVYKKLKEENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQLHYHRSEHWVVVRGTA
KVRVGDKEFILRPGESTFIPAGVIHRLENPGKVVLEVIETQIGEYLGEDDIVRIEDDYQRA

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=477, Percent_Identity=42.5576519916143, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 52622; Mature: 52622

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLILAGGKGTRLWPLSRELMPKQFIKVFSNKSLFQKTVERALIFSKPKEIFVVTNKEY
CCEEEEECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCE
RFRVLDDLNEIGVNIPEENILLEPVGKNTLPAIYWGLKVIDESFGDSIVAVLPSDHAIDV
EEEEHHCHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEC
NENYIEAFKKAEKLAENYLVTFGIKPTKPHTGYGYIKPGEKISNLGFLVDEFKEKPDLET
CHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHH
AKRYVENGYYWNSGMFMFRTTLFMEEARKHAPDVVKAFEEGKTIEEAYELAPEISVDYGI
HHHHHHCCEEECCCEEEHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCCEECCCC
MEKTDKAAVVPLNTYWNDLGSFDAVYEALQKDENGNAVEVRGFKAKYINVDSKNNLILTE
CCCCCCEEEEECHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCEEEEE
RLTATVGVEDLIIVDTGDALLVAKKGETQKVKEVYKKLKEENDERAIVHRTAYRPWGSYT
EEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEE
VLEEGERYKIKRITVLPGKRLSLQLHYHRSEHWVVVRGTAKVRVGDKEFILRPGESTFIP
EEECCCEEEEEEEEECCCCEEEEEEEEECCCCEEEEECCEEEEECCHHEEEECCCCCEEC
AGVIHRLENPGKVVLEVIETQIGEYLGEDDIVRIEDDYQRA
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKTLILAGGKGTRLWPLSRELMPKQFIKVFSNKSLFQKTVERALIFSKPKEIFVVTNKEY
CCEEEEECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCE
RFRVLDDLNEIGVNIPEENILLEPVGKNTLPAIYWGLKVIDESFGDSIVAVLPSDHAIDV
EEEEHHCHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEC
NENYIEAFKKAEKLAENYLVTFGIKPTKPHTGYGYIKPGEKISNLGFLVDEFKEKPDLET
CHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHH
AKRYVENGYYWNSGMFMFRTTLFMEEARKHAPDVVKAFEEGKTIEEAYELAPEISVDYGI
HHHHHHCCEEECCCEEEHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCCEECCCC
MEKTDKAAVVPLNTYWNDLGSFDAVYEALQKDENGNAVEVRGFKAKYINVDSKNNLILTE
CCCCCCEEEEECHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCEEEEE
RLTATVGVEDLIIVDTGDALLVAKKGETQKVKEVYKKLKEENDERAIVHRTAYRPWGSYT
EEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEE
VLEEGERYKIKRITVLPGKRLSLQLHYHRSEHWVVVRGTAKVRVGDKEFILRPGESTFIP
EEECCCEEEEEEEEECCCCEEEEEEEEECCCCEEEEECCEEEEECCHHEEEECCCCCEEC
AGVIHRLENPGKVVLEVIETQIGEYLGEDDIVRIEDDYQRA
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]