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The map label for this gene is aspC [H]

Identifier: 18976894

GI number: 18976894

Start: 540820

End: 541992

Strand: Reverse

Name: aspC [H]

Synonym: PF0522

Alternate gene names: 18976894

Gene position: 541992-540820 (Counterclockwise)

Preceding gene: 18976895

Following gene: 18976893

Centisome position: 28.4

GC content: 41.52

Gene sequence:

>1173_bases
ATGAAAGAAAAGAGGAAATATTTTATGGCCCACAGAATTGGAGTTATCCAGCGTTCAAAGATTAGAGAGTTGTTTGAAAG
AGCATCTAAAATGGAAAACGTGATATCTCTTGGTATAGGTGAGCCTGACTTTGATACCCCGAATAACATAAAGGAAGCTG
CAAAGAGAGCCTTAGACGAAGGGTGGACTCATTACACTCCAAATGCCGGAATTCCAGAGCTAAGAGAAGCTATCGCGGAA
TACTACAAGAAGTTCTATGGAATTGATGTGGAAGTAGACAACGTTTTGGTGACTGCTGGAGCTTATGAAGCCACATATCT
TGCATTTGAGACCATGCTAGAGCAGGGGGATGAGGTAATTATACCAGACCCAGCATTCGTTTGTTATGTTGAAGATGCGA
AGCTTGCAGAGGCAAAGCCCATAAGACTACCTCTAAGGGAGGAAAATGACTTCAAGCCAGATATAGACGAGCTACTAGAA
AGAATTACAAAGAGAACTAGGATGATAGTCATAAACTATCCAAACAACCCAACCGGAGCAGTTTTAGATAAGGAGACAGC
CAAAGCTATAGCGGATGTTGCTGAGGATTATAACATTTACATTCTGAGTGATGAACCCTATGAGCACTTCTTATATGATG
ATGCAAAGCACTATCCAATGATAAAATTTGCTCCCGACAATACCATTCTCGCAAACTCATTCTCGAAGACTTTCGCAATG
ACTGGATGGAGACTTGGATTTGTCATAGCACCTACCCAAATAATAAGGGAAATGATTAAACTCCACGCCTACATAATAGG
GAATGTTGCTTCGTTCGTCCAAGTTGCTGGAATAGAAGCTCTCAGAAGTAAAGAAAGTTGGAAGGCAGTGGAAGAGATGA
GAAAAGAATACAACGAGAGAAGAAAACTAGTCCTACAAAGATTGAGAAAAATGCCATACATAAAGGTAAGAGAGCCCAAG
GGAGCATTCTACGTATTCCCCAATATAAGCGAGACCGAGATGAGTAGCGAGGAATTCAGTGAGTGGTTGCTAGAGAAGGC
CAAGGTAGTAGTGATCCCAGGAACGGCCTTTGGAGAAAATGGAGAGGGATATGTGAGAATTAGCTATGCAACAAGCAGAG
AAAAACTTATAGAGGCAATGGACAGGATAGAAAAGGCCCTAGAAGAAATATAG

Upstream 100 bases:

>100_bases
ATTTTTGATAGAACCTTAAAAAAGCCTAAAACCGCTTTTTAATCCCAAACTCCAAAGAATTTATAAAGAATTTCCCTATT
CCCCCATGAGGGAACTCCGT

Downstream 100 bases:

>100_bases
AGGGATAATTATGAAAGAAATTCTTAGCATTTTCATTGCAATCTTTTTAGCCGAATTTGGAGATAAGACTCAGCTAGCTA
CAATAGCTTTTGCCTCTAAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKEKRKYFMAHRIGVIQRSKIRELFERASKMENVISLGIGEPDFDTPNNIKEAAKRALDEGWTHYTPNAGIPELREAIAE
YYKKFYGIDVEVDNVLVTAGAYEATYLAFETMLEQGDEVIIPDPAFVCYVEDAKLAEAKPIRLPLREENDFKPDIDELLE
RITKRTRMIVINYPNNPTGAVLDKETAKAIADVAEDYNIYILSDEPYEHFLYDDAKHYPMIKFAPDNTILANSFSKTFAM
TGWRLGFVIAPTQIIREMIKLHAYIIGNVASFVQVAGIEALRSKESWKAVEEMRKEYNERRKLVLQRLRKMPYIKVREPK
GAFYVFPNISETEMSSEEFSEWLLEKAKVVVIPGTAFGENGEGYVRISYATSREKLIEAMDRIEKALEEI

Sequences:

>Translated_390_residues
MKEKRKYFMAHRIGVIQRSKIRELFERASKMENVISLGIGEPDFDTPNNIKEAAKRALDEGWTHYTPNAGIPELREAIAE
YYKKFYGIDVEVDNVLVTAGAYEATYLAFETMLEQGDEVIIPDPAFVCYVEDAKLAEAKPIRLPLREENDFKPDIDELLE
RITKRTRMIVINYPNNPTGAVLDKETAKAIADVAEDYNIYILSDEPYEHFLYDDAKHYPMIKFAPDNTILANSFSKTFAM
TGWRLGFVIAPTQIIREMIKLHAYIIGNVASFVQVAGIEALRSKESWKAVEEMRKEYNERRKLVLQRLRKMPYIKVREPK
GAFYVFPNISETEMSSEEFSEWLLEKAKVVVIPGTAFGENGEGYVRISYATSREKLIEAMDRIEKALEEI
>Mature_390_residues
MKEKRKYFMAHRIGVIQRSKIRELFERASKMENVISLGIGEPDFDTPNNIKEAAKRALDEGWTHYTPNAGIPELREAIAE
YYKKFYGIDVEVDNVLVTAGAYEATYLAFETMLEQGDEVIIPDPAFVCYVEDAKLAEAKPIRLPLREENDFKPDIDELLE
RITKRTRMIVINYPNNPTGAVLDKETAKAIADVAEDYNIYILSDEPYEHFLYDDAKHYPMIKFAPDNTILANSFSKTFAM
TGWRLGFVIAPTQIIREMIKLHAYIIGNVASFVQVAGIEALRSKESWKAVEEMRKEYNERRKLVLQRLRKMPYIKVREPK
GAFYVFPNISETEMSSEEFSEWLLEKAKVVVIPGTAFGENGEGYVRISYATSREKLIEAMDRIEKALEEI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=415, Percent_Identity=26.0240963855422, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI169881279, Length=415, Percent_Identity=26.0240963855422, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=28.1012658227848, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI56713256, Length=395, Percent_Identity=28.1012658227848, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=27.4406332453826, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI169881281, Length=412, Percent_Identity=21.8446601941748, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19263340, Length=398, Percent_Identity=23.6180904522613, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=23.6180904522613, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7705897, Length=369, Percent_Identity=24.1192411924119, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI33469970, Length=369, Percent_Identity=24.1192411924119, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786816, Length=388, Percent_Identity=28.3505154639175, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=30.7065217391304, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1788627, Length=352, Percent_Identity=30.9659090909091, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1787710, Length=331, Percent_Identity=25.3776435045317, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787909, Length=394, Percent_Identity=20.3045685279188, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790797, Length=393, Percent_Identity=23.6641221374046, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994949, Length=314, Percent_Identity=22.6114649681529, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=397, Percent_Identity=28.7153652392947, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=27.8061224489796, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=27.8061224489796, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=366, Percent_Identity=29.5081967213115, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI115534666, Length=351, Percent_Identity=23.3618233618234, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71981209, Length=403, Percent_Identity=23.8213399503722, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=355, Percent_Identity=27.3239436619718, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=404, Percent_Identity=27.2277227722772, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323118, Length=351, Percent_Identity=24.5014245014245, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321236, Length=402, Percent_Identity=24.6268656716418, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=26.1658031088083, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=26.1658031088083, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=26.1658031088083, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=26.1658031088083, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI18859735, Length=394, Percent_Identity=22.3350253807107, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356535, Length=413, Percent_Identity=23.2445520581114, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44887; Mature: 44887

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKRKYFMAHRIGVIQRSKIRELFERASKMENVISLGIGEPDFDTPNNIKEAAKRALDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GWTHYTPNAGIPELREAIAEYYKKFYGIDVEVDNVLVTAGAYEATYLAFETMLEQGDEVI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCEEEECCCHHHHHHHHHHHHHCCCEEE
IPDPAFVCYVEDAKLAEAKPIRLPLREENDFKPDIDELLERITKRTRMIVINYPNNPTGA
ECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCC
VLDKETAKAIADVAEDYNIYILSDEPYEHFLYDDAKHYPMIKFAPDNTILANSFSKTFAM
EECHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCEEEECCCCCEECCCHHHHHHH
TGWRLGFVIAPTQIIREMIKLHAYIIGNVASFVQVAGIEALRSKESWKAVEEMRKEYNER
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
RKLVLQRLRKMPYIKVREPKGAFYVFPNISETEMSSEEFSEWLLEKAKVVVIPGTAFGEN
HHHHHHHHHHCCCEEEECCCCCEEECCCCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCC
GEGYVRISYATSREKLIEAMDRIEKALEEI
CCCEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEKRKYFMAHRIGVIQRSKIRELFERASKMENVISLGIGEPDFDTPNNIKEAAKRALDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GWTHYTPNAGIPELREAIAEYYKKFYGIDVEVDNVLVTAGAYEATYLAFETMLEQGDEVI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCEEEECCCHHHHHHHHHHHHHCCCEEE
IPDPAFVCYVEDAKLAEAKPIRLPLREENDFKPDIDELLERITKRTRMIVINYPNNPTGA
ECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCC
VLDKETAKAIADVAEDYNIYILSDEPYEHFLYDDAKHYPMIKFAPDNTILANSFSKTFAM
EECHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCEEEECCCCCEECCCHHHHHHH
TGWRLGFVIAPTQIIREMIKLHAYIIGNVASFVQVAGIEALRSKESWKAVEEMRKEYNER
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
RKLVLQRLRKMPYIKVREPKGAFYVFPNISETEMSSEEFSEWLLEKAKVVVIPGTAFGEN
HHHHHHHHHHCCCEEEECCCCCEEECCCCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCC
GEGYVRISYATSREKLIEAMDRIEKALEEI
CCCEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]