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The map label for this gene is yfjP [H]

Identifier: 18976883

GI number: 18976883

Start: 530974

End: 531792

Strand: Reverse

Name: yfjP [H]

Synonym: PF0511

Alternate gene names: 18976883

Gene position: 531792-530974 (Counterclockwise)

Preceding gene: 18976885

Following gene: 18976882

Centisome position: 27.87

GC content: 37.97

Gene sequence:

>819_bases
ATGATTGATCTAAAAAAGACCACTCATGAGATGATCAAGAACGGAACTTGGAAATTTGAGAATGGAATCTTTTGGCAAGC
TCTTCCCTCAGGAGTTGTTGGTTACAATGGAGAAGACTTTACATTTCCAGATCACTTTGGGAAAAGGGAAAAGAAAGAAG
CAGAAGAGAGAATAAGGTTTATTTTAGGCCTTGATACAAATTTAGAAAAATTTTACTCAGAAATTCAAGATTCGAAGTTT
GCCTTTCTTGTAGATGAGTTTTATGGTTTAACCATGCCAGCTGCCCCAACACCATATCAGGCAATTGTTGAAGTTATAGC
CCAACAACAGATAAGCTTTGAATTCGCACAGAAAGCAATCTACAACCTAGTTAAACTTATTGGTAAAAGAATTGGAGACC
TCTATCTCTTTCCTGAGCCCAAAGATATACTAAAACTTGGGGAAAGAATAAAGGAAGCAAAGCTTGGATACAGAGGGGAT
TACATATTGAACATTACCCAAGAATACGTAAAAGGGAATTTAAGGCTAGACTTATGGGAATTAAATGAGAAAGATGCAAC
AAAGTACCTCACTAAGTTTAGAGGGATAGGAAGGTGGAGTGCTGAGCTATTTTTAATGTATGGGCTTAGGAAAAATGTTT
ATCCCGCGAGCGACCTAGGATTGAGAAGGGGAATAGCAAAAATATTTGGGCTACCTCTAAAGAAGGTTACTGAGAGGACT
GTTAGGGAGATCATTGAACCCTATGGGAAGTGGAAAAGCCTTTTGGCATTTTACATCCTGTGTTATGATAGAAAGACAGA
AATGGAGGTGAGGAAATGA

Upstream 100 bases:

>100_bases
AGCAATGTTAAAAAATAATATGGTCATTAATAAGATGCGCGATGAAGAAAGCGAACTGCTCTGAGAGATGATGAAAAGGG
CCTAACAGAGCGTGAGAGGC

Downstream 100 bases:

>100_bases
GAATCAGAGAGTTCCAAGAAATGATCAAGGAGATTTACTATCACAAAGACAAGAAGAGGGGAGTGGAAAAAACTTTCTTC
TGGTTTGTTGAGGAAGTGGG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIDLKKTTHEMIKNGTWKFENGIFWQALPSGVVGYNGEDFTFPDHFGKREKKEAEERIRFILGLDTNLEKFYSEIQDSKF
AFLVDEFYGLTMPAAPTPYQAIVEVIAQQQISFEFAQKAIYNLVKLIGKRIGDLYLFPEPKDILKLGERIKEAKLGYRGD
YILNITQEYVKGNLRLDLWELNEKDATKYLTKFRGIGRWSAELFLMYGLRKNVYPASDLGLRRGIAKIFGLPLKKVTERT
VREIIEPYGKWKSLLAFYILCYDRKTEMEVRK

Sequences:

>Translated_272_residues
MIDLKKTTHEMIKNGTWKFENGIFWQALPSGVVGYNGEDFTFPDHFGKREKKEAEERIRFILGLDTNLEKFYSEIQDSKF
AFLVDEFYGLTMPAAPTPYQAIVEVIAQQQISFEFAQKAIYNLVKLIGKRIGDLYLFPEPKDILKLGERIKEAKLGYRGD
YILNITQEYVKGNLRLDLWELNEKDATKYLTKFRGIGRWSAELFLMYGLRKNVYPASDLGLRRGIAKIFGLPLKKVTERT
VREIIEPYGKWKSLLAFYILCYDRKTEMEVRK
>Mature_272_residues
MIDLKKTTHEMIKNGTWKFENGIFWQALPSGVVGYNGEDFTFPDHFGKREKKEAEERIRFILGLDTNLEKFYSEIQDSKF
AFLVDEFYGLTMPAAPTPYQAIVEVIAQQQISFEFAQKAIYNLVKLIGKRIGDLYLFPEPKDILKLGERIKEAKLGYRGD
YILNITQEYVKGNLRLDLWELNEKDATKYLTKFRGIGRWSAELFLMYGLRKNVYPASDLGLRRGIAKIFGLPLKKVTERT
VREIIEPYGKWKSLLAFYILCYDRKTEMEVRK

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 31801; Mature: 31801

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLKKTTHEMIKNGTWKFENGIFWQALPSGVVGYNGEDFTFPDHFGKREKKEAEERIRF
CCCCHHHHHHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHH
ILGLDTNLEKFYSEIQDSKFAFLVDEFYGLTMPAAPTPYQAIVEVIAQQQISFEFAQKAI
HHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YNLVKLIGKRIGDLYLFPEPKDILKLGERIKEAKLGYRGDYILNITQEYVKGNLRLDLWE
HHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEE
LNEKDATKYLTKFRGIGRWSAELFLMYGLRKNVYPASDLGLRRGIAKIFGLPLKKVTERT
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VREIIEPYGKWKSLLAFYILCYDRKTEMEVRK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIDLKKTTHEMIKNGTWKFENGIFWQALPSGVVGYNGEDFTFPDHFGKREKKEAEERIRF
CCCCHHHHHHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHH
ILGLDTNLEKFYSEIQDSKFAFLVDEFYGLTMPAAPTPYQAIVEVIAQQQISFEFAQKAI
HHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YNLVKLIGKRIGDLYLFPEPKDILKLGERIKEAKLGYRGDYILNITQEYVKGNLRLDLWE
HHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEE
LNEKDATKYLTKFRGIGRWSAELFLMYGLRKNVYPASDLGLRRGIAKIFGLPLKKVTERT
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VREIIEPYGKWKSLLAFYILCYDRKTEMEVRK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]