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The map label for this gene is 18976833

Identifier: 18976833

GI number: 18976833

Start: 476258

End: 476839

Strand: Direct

Name: 18976833

Synonym: PF0461

Alternate gene names: NA

Gene position: 476258-476839 (Clockwise)

Preceding gene: 18976832

Following gene: 18976834

Centisome position: 24.96

GC content: 39.52

Gene sequence:

>582_bases
ATGATAGTTGTGTTAAGACTAGGCCACAGACCAGAAAGAGACAAGAGGGTAACTACCCATGTAGCATTAACAGCGAGAGC
TTTTGGAGCTGATGGAATAATAATTGCTGGAGAAGAAGATGAAAAGGTTAAAGAGAGCGTGGAGGATGTAGTGAAGAGAT
GGGGTGGGTCGTTCTTCATTAGGTTTGAAAAAAACTGGAGAAAAGAGATAAAGGAATTTAGAGGAATAAAAGTGCACTTG
ACGATGTATGGACTACATGTTGACGATATAATAGAGGATATTAAAGCGAAATTTAGAGAAGGGAATGACATAATGGTGAT
AGTAGGAGCTGAAAAAGTTCCGAGAGAAGTTTATGAGCTAGCTGATTACAATGTTGCTATAGGAAATCAACCTCATAGCG
AAGTTGCTGCTCTTGCAGTCTTCTTGGATAGACTTTTGGAAGGAAAAGGATTAAAAAAGGAGTTTAAGAATGCAAAACTT
AGGATAATACCGCAAGAACGCGGGAAAAAAGTAGTGGAGGTTGAAAGCAGTGCTGAGCAATTTGAGACCATTGGCGAAAA
AGCCACTGGAAAAGATAGCTGA

Upstream 100 bases:

>100_bases
AGCACTATACCAGTTTTATTATGACATAGAATGGGAGGAAGATTTTAGAGTATATTGGGTAAAGCTAATGCAGATTTACA
GCTAGAGGGGTGTTCCAATC

Downstream 100 bases:

>100_bases
GCCATTCTCAAAGCTTGGCATAACTCCTAATCAACTCACTATGGTTGGATTTTTCCTGTCTTTACTTGCATCTTATGAAT
ATTACCTCAATAATCAGGTT

Product: tRNA 2'-O-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIAGEEDEKVKESVEDVVKRWGGSFFIRFEKNWRKEIKEFRGIKVHL
TMYGLHVDDIIEDIKAKFREGNDIMVIVGAEKVPREVYELADYNVAIGNQPHSEVAALAVFLDRLLEGKGLKKEFKNAKL
RIIPQERGKKVVEVESSAEQFETIGEKATGKDS

Sequences:

>Translated_193_residues
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIAGEEDEKVKESVEDVVKRWGGSFFIRFEKNWRKEIKEFRGIKVHL
TMYGLHVDDIIEDIKAKFREGNDIMVIVGAEKVPREVYELADYNVAIGNQPHSEVAALAVFLDRLLEGKGLKKEFKNAKL
RIIPQERGKKVVEVESSAEQFETIGEKATGKDS
>Mature_193_residues
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIAGEEDEKVKESVEDVVKRWGGSFFIRFEKNWRKEIKEFRGIKVHL
TMYGLHVDDIIEDIKAKFREGNDIMVIVGAEKVPREVYELADYNVAIGNQPHSEVAALAVFLDRLLEGKGLKKEFKNAKL
RIIPQERGKKVVEVESSAEQFETIGEKATGKDS

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRM56_PYRFU (Q8U3K5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578190.1
- ProteinModelPortal:   Q8U3K5
- SMR:   Q8U3K5
- EnsemblBacteria:   EBPYRT00000004973
- GeneID:   1468302
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0461
- NMPDR:   fig|186497.1.peg.473
- GeneTree:   EBGT00050000023370
- HOGENOM:   HBG297370
- OMA:   GHRPERD
- ProtClustDB:   PRK03958
- GO:   GO:0005737
- HAMAP:   MF_00077
- InterPro:   IPR002845
- PIRSF:   PIRSF016123
- ProDom:   PD016584

Pfam domain/function: PF01994 DUF127

EC number: NA

Molecular weight: Translated: 21872; Mature: 21872

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: BINDING 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIAGEEDEKVKESVEDVVKRWGGSFFI
CEEEEECCCCCCCCCCHHHHEEEEEHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEE
RFEKNWRKEIKEFRGIKVHLTMYGLHVDDIIEDIKAKFREGNDIMVIVGAEKVPREVYEL
EECHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
ADYNVAIGNQPHSEVAALAVFLDRLLEGKGLKKEFKNAKLRIIPQERGKKVVEVESSAEQ
HCCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEEHHHCCEEEEECHHHHH
FETIGEKATGKDS
HHHHCCCCCCCCC
>Mature Secondary Structure
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIAGEEDEKVKESVEDVVKRWGGSFFI
CEEEEECCCCCCCCCCHHHHEEEEEHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEEEE
RFEKNWRKEIKEFRGIKVHLTMYGLHVDDIIEDIKAKFREGNDIMVIVGAEKVPREVYEL
EECHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
ADYNVAIGNQPHSEVAALAVFLDRLLEGKGLKKEFKNAKLRIIPQERGKKVVEVESSAEQ
HCCCEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEEHHHCCEEEEECHHHHH
FETIGEKATGKDS
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA