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The map label for this gene is pls

Identifier: 18976659

GI number: 18976659

Start: 297558

End: 301754

Strand: Direct

Name: pls

Synonym: PF0287

Alternate gene names: 18976659

Gene position: 297558-301754 (Clockwise)

Preceding gene: 18976658

Following gene: 18976661

Centisome position: 15.59

GC content: 43.2

Gene sequence:

>4197_bases
ATGAATAAGAAGGGACTTACTGTGCTATTTATAGCGATAATGCTCCTTTCAGTAGTTCCAGTGCACTTTGTGTCCGCAGG
AACACCACCGGTTAGTTCAGAAAATTCAACAACTTCTATACTCCCTAACCAACAAGTTGTGACAAAAGAAGTTTCACAAG
CGGCGCTTAATGCTATAATGAAAGGACAACCCAACATGGTTCTTATAATCAAGACTAAGGAAGGCAAACTTGAAGAGGCA
AAAACCGAGCTTGAAAAGCTAGGTGCAGAGATTCTTGACGAAAATAGAGTTCTTAACATGTTGCTAGTTAAGATTAAGCC
TGAGAAAGTTAAAGAGCTCAACTATATCTCATCTCTTGAAAAAGCCTGGCTTAACAGAGAAGTTAAGCTTTCCCCTCCAA
TTGTCGAAAAGGACGTCAAGACTAAGGAGCCCTCCCTAGAACCAAAAATGTATAACAGCACCTGGGTAATTAATGCTCTC
CAGTTCATCCAGGAATTTGGATATGATGGTAGTGGTGTTGTTGTTGCAGTACTTGACACGGGAGTTGATCCGAACCATCC
TTTCTTGAGCATAACTCCAGATGGACGCAGGAAAATTATAGAATGGAAGGATTTTACAGACGAGGGATTCGTGGATACAT
CATTCAGCTTTAGCAAGGTTGTAAATGGGACTCTTATAATTAACACAACATTCCAAGTGGCCTCAGGTCTCACGCTGAAT
GAATCGACAGGACTTATGGAATACGTTGTTAAGACTGTTTACGTGAGCAATGTGACCATTGGAAATATCACTTCTGCTAA
TGGCATCTATCACTTCGGCCTGCTCCCAGAAAGATACTTCGACTTAAACTTCGATGGTGATCAAGAGGACTTCTATCCTG
TCTTATTAGTTAACTCCACTGGCAATGGTTATGACATTGCATATGTGGATACTGACCTTGACTACGACTTCACCGACGAA
GTTCCACTTGGCCAGTACAACGTTACTTATGATGTTGCTGTTTTTAGCTACTACTACGGTCCTCTCAACTACGTGCTTGC
AGAAATAGATCCTAACGGAGAATATGCAGTATTTGGGTGGGATGGTCACGGTCACGGAACTCACGTAGCTGGAACTGTTG
CTGGTTACGACAGCAACAATGATGCTTGGGATTGGCTCAGTATGTACTCTGGTGAATGGGAAGTGTTCTCAAGACTCTAT
GGTTGGGATTATACGAACGTTACCACAGACACCGTGCAGGGTGTTGCTCCAGGTGCCCAAATAATGGCAATAAGAGTTCT
TAGGAGTGATGGACGGGGTAGCATGTGGGATATTATAGAAGGTATGACATACGCAGCAACCCATGGTGCAGACGTTATAA
GCATGAGTCTCGGTGGAAATGCTCCATACTTAGATGGTACTGATCCAGAAAGCGTTGCTGTGGATGAGCTTACCGAAAAG
TACGGTGTTGTATTCGTAATAGCTGCAGGAAATGAAGGTCCTGGCATTAACATCGTTGGAAGTCCTGGTGTTGCAACAAA
GGCAATAACTGTTGGAGCTGCTGCAGTGCCCATTAACGTTGGAGTTTATGTTTCCCAAGCACTTGGATATCCTGATTACT
ATGGATTCTATTACTTCCCCGCCTACACAAACGTTAGAATAGCATTCTTCTCAAGCAGAGGGCCGAGAATAGATGGTGAA
ATAAAACCCAATGTAGTGGCTCCAGGTTACGGAATTTACTCATCCCTGCCGATGTGGATTGGCGGAGCTGACTTCATGTC
TGGAACTTCGATGGCTACTCCACATGTCAGCGGTGTCGTTGCACTCCTCATAAGCGGGGCAAAGGCCGAGGGAATATACT
ACAATCCAGATATAATTAAGAAGGTTCTTGAGAGCGGTGCAACCTGGCTTGAGGGAGATCCATATACTGGGCAGAAGTAC
ACTGAGCTTGACCAAGGTCATGGTCTTGTTAACGTTACCAAGTCCTGGGAAATCCTTAAGGCTATAAACGGCACCACTCT
CCCAATTGTTGATCACTGGGCAGACAAGTCCTACAGCGACTTTGCGGAGTACTTGGGTGTGGACGTTATAAGAGGTCTCT
ACGCAAGGAACTCTATACCTGACATTGTCGAGTGGCACATTAAGTACGTAGGGGACACGGAGTACAGAACTTTTGAGATC
TATGCAACTGAGCCATGGATTAAGCCTTTTGTCAGTGGAAGTGTAATTCTAGAGAACAATACCGAGTTTGTCCTTAGGGT
GAAATATGATGTAGAGGGTCTTGAGCCAGGTCTCTATGTTGGAAGGATAATCATTGATGATCCAACAACGCCAGTTATTG
AAGACGAGATCTTGAACACAATTGTTATTCCCGAGAAGTTCACTCCTGAGAACAATTACACCCTCACCTGGTATGATATT
AATGGTCCAGAAATGGTGACTCACCACTTCTTCACTGTGCCTGAGGGAGTGGACGTTCTCTACGCGATGACCACATACTG
GGACTACGGTCTGTACAGACCAGATGGAATGTTTGTGTTCCCATACCAGCTAGATTATCTTCCCGCTGCAGTCTCAAATC
CAATGCCTGGAAACTGGGAGCTAGTATGGACTGGATTTAACTTTGCACCCCTCTATGAGTCGGGCTTCCTTGTAAGGATT
TACGGAGTAGAGATAACTCCAAGCGTTTGGTACATTAACAGGACATACCTTGACACTAACACTGAATTCTCAATTGAATT
CAATATTACTAACATCTATGCCCCAATTAATGCAACTCTAATCCCCATTGGCCTTGGAACCTACAATGCGAGCGTTGAAA
GCGTTGGTGATGGAGAGTTCTTCATAAAGGGCATTGAAGTTCCTGAAGGCACCGCAGAGTTGAAGATTAGGATAGGCAAC
CCAAGTGTTCCGAATTCAGATCTAGACTTGTACCTTTATGACAGTAAAGGCAATTTAGTGGCCTTAGATGGAAACCCAAC
AGCAGAAGAAGAGGTTGTAGTTGAGTATCCTAAGCCTGGAGTTTATTCAATAGTAGTACATGGTTACAGCGTCAGGGACG
AAAATGGTAATCCAACGACAACCACCTTTGACTTAGTTGTTCAAATGACCCTTGATAATGGAAACATAAAGCTTGACAAA
GACTCGATTATTCTTGGAAGCAATGAAAGCGTAGTTGTAACTGCAAACATAACAATTGATAGAGATCATCCTACAGGAGT
ATACTCTGGTATCATAGAGATTAGAGATAATGAGGTCTACCAGGATACAAATACTTCAATTGCGAAAATACCCATAACTT
TGGTAATTGACAAGGCGGACTTTGCCGTTGGTCTCACACCAGCAGAGGGAGTACTTGGAGAGGCTAGAAATTACACTCTA
ATTGTAAAGCATGCCCTAACACTAGAGCCTGTGCCAAATGCTACAGTGATTATAGGAAACTACACCTACCTCACAGACGA
AAACGGTACAGTGACATTCACGTATGCTCCAACTAAGTTAGGCAGTGATGAAATCACAGTCATAGTTAAGAAAGAGAACT
TCAACACATTAGAGAAGACCTTCCAAATCACAGTATCAGAGCCTGAAATAACTGAAGAGGACATAAATGAGCCCAAGCTT
GCAATGTCATCACCAGAAGCAAATGCTACCATAGTATCAGTTGAGATGGAGAGTGAGGGTGGCGTTAAAAAGACAGTGAC
AGTGGAAATAACTATAAACGGAACCGCTAATGAGACTGCAACAATAGTGGTTCCTGTTCCTAAGAAGGCCGAAAACATCG
AGGTAAGTGGAGACCACGTAATTTCCTATAGTATAGAGGAAGGAGAGTACGCCAAGTACGTTATAATTACAGTGAAGTTT
GCATCACCTGTAACAGTAACTGTTACTTACACTATCTATGCTGGCCCAAGAGTCTCAATCTTGACACTTAACTTCCTTGG
CTACTCATGGTACAGACTATATTCACAGAAGTTTGACGAATTGTACCAAAAGGCCCTTGAATTGGGAGTGGACAACGAGA
CATTAGCTTTAGCCCTCAGCTACCATGAAAAAGCCAAAGAGTACTACGAAAAGGCCCTTGAGCTTAGCGAGGGTAACATA
ATCCAATACCTTGGAGACATAAGACTATTACCTCCATTAAGACAGGCATACATCAATGAAATGAAGGCAGTTAAGATACT
GGAAAAGGCCATAGAAGAATTAGAGGGTGAAGAGTAA

Upstream 100 bases:

>100_bases
TCCGAGTGATGAGTAAGATACATCATTACAGTCCCAAAATGTTTATAATTGGAACGCAGTGAATATACAAAATGAATATA
ACCTCGGAGGTGACTGTAGA

Downstream 100 bases:

>100_bases
TCTCCAATTTTTCCCACTTTTTCTTTTATAACATTCCAAGCCTTTTCTTAGCTTCTTCGCTCATTCTATCAGGAGTCCAT
GGAGGATCAAAGGTAAGTTC

Product: pyrolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1398; Mature: 1398

Protein sequence:

>1398_residues
MNKKGLTVLFIAIMLLSVVPVHFVSAGTPPVSSENSTTSILPNQQVVTKEVSQAALNAIMKGQPNMVLIIKTKEGKLEEA
KTELEKLGAEILDENRVLNMLLVKIKPEKVKELNYISSLEKAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINAL
QFIQEFGYDGSGVVVAVLDTGVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLN
ESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPERYFDLNFDGDQEDFYPVLLVNSTGNGYDIAYVDTDLDYDFTDE
VPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGEYAVFGWDGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLY
GWDYTNVTTDTVQGVAPGAQIMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPESVAVDELTEK
YGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQALGYPDYYGFYYFPAYTNVRIAFFSSRGPRIDGE
IKPNVVAPGYGIYSSLPMWIGGADFMSGTSMATPHVSGVVALLISGAKAEGIYYNPDIIKKVLESGATWLEGDPYTGQKY
TELDQGHGLVNVTKSWEILKAINGTTLPIVDHWADKSYSDFAEYLGVDVIRGLYARNSIPDIVEWHIKYVGDTEYRTFEI
YATEPWIKPFVSGSVILENNTEFVLRVKYDVEGLEPGLYVGRIIIDDPTTPVIEDEILNTIVIPEKFTPENNYTLTWYDI
NGPEMVTHHFFTVPEGVDVLYAMTTYWDYGLYRPDGMFVFPYQLDYLPAAVSNPMPGNWELVWTGFNFAPLYESGFLVRI
YGVEITPSVWYINRTYLDTNTEFSIEFNITNIYAPINATLIPIGLGTYNASVESVGDGEFFIKGIEVPEGTAELKIRIGN
PSVPNSDLDLYLYDSKGNLVALDGNPTAEEEVVVEYPKPGVYSIVVHGYSVRDENGNPTTTTFDLVVQMTLDNGNIKLDK
DSIILGSNESVVVTANITIDRDHPTGVYSGIIEIRDNEVYQDTNTSIAKIPITLVIDKADFAVGLTPAEGVLGEARNYTL
IVKHALTLEPVPNATVIIGNYTYLTDENGTVTFTYAPTKLGSDEITVIVKKENFNTLEKTFQITVSEPEITEEDINEPKL
AMSSPEANATIVSVEMESEGGVKKTVTVEITINGTANETATIVVPVPKKAENIEVSGDHVISYSIEEGEYAKYVIITVKF
ASPVTVTVTYTIYAGPRVSILTLNFLGYSWYRLYSQKFDELYQKALELGVDNETLALALSYHEKAKEYYEKALELSEGNI
IQYLGDIRLLPPLRQAYINEMKAVKILEKAIEELEGEE

Sequences:

>Translated_1398_residues
MNKKGLTVLFIAIMLLSVVPVHFVSAGTPPVSSENSTTSILPNQQVVTKEVSQAALNAIMKGQPNMVLIIKTKEGKLEEA
KTELEKLGAEILDENRVLNMLLVKIKPEKVKELNYISSLEKAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINAL
QFIQEFGYDGSGVVVAVLDTGVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLN
ESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPERYFDLNFDGDQEDFYPVLLVNSTGNGYDIAYVDTDLDYDFTDE
VPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGEYAVFGWDGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLY
GWDYTNVTTDTVQGVAPGAQIMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPESVAVDELTEK
YGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQALGYPDYYGFYYFPAYTNVRIAFFSSRGPRIDGE
IKPNVVAPGYGIYSSLPMWIGGADFMSGTSMATPHVSGVVALLISGAKAEGIYYNPDIIKKVLESGATWLEGDPYTGQKY
TELDQGHGLVNVTKSWEILKAINGTTLPIVDHWADKSYSDFAEYLGVDVIRGLYARNSIPDIVEWHIKYVGDTEYRTFEI
YATEPWIKPFVSGSVILENNTEFVLRVKYDVEGLEPGLYVGRIIIDDPTTPVIEDEILNTIVIPEKFTPENNYTLTWYDI
NGPEMVTHHFFTVPEGVDVLYAMTTYWDYGLYRPDGMFVFPYQLDYLPAAVSNPMPGNWELVWTGFNFAPLYESGFLVRI
YGVEITPSVWYINRTYLDTNTEFSIEFNITNIYAPINATLIPIGLGTYNASVESVGDGEFFIKGIEVPEGTAELKIRIGN
PSVPNSDLDLYLYDSKGNLVALDGNPTAEEEVVVEYPKPGVYSIVVHGYSVRDENGNPTTTTFDLVVQMTLDNGNIKLDK
DSIILGSNESVVVTANITIDRDHPTGVYSGIIEIRDNEVYQDTNTSIAKIPITLVIDKADFAVGLTPAEGVLGEARNYTL
IVKHALTLEPVPNATVIIGNYTYLTDENGTVTFTYAPTKLGSDEITVIVKKENFNTLEKTFQITVSEPEITEEDINEPKL
AMSSPEANATIVSVEMESEGGVKKTVTVEITINGTANETATIVVPVPKKAENIEVSGDHVISYSIEEGEYAKYVIITVKF
ASPVTVTVTYTIYAGPRVSILTLNFLGYSWYRLYSQKFDELYQKALELGVDNETLALALSYHEKAKEYYEKALELSEGNI
IQYLGDIRLLPPLRQAYINEMKAVKILEKAIEELEGEE
>Mature_1398_residues
MNKKGLTVLFIAIMLLSVVPVHFVSAGTPPVSSENSTTSILPNQQVVTKEVSQAALNAIMKGQPNMVLIIKTKEGKLEEA
KTELEKLGAEILDENRVLNMLLVKIKPEKVKELNYISSLEKAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINAL
QFIQEFGYDGSGVVVAVLDTGVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLN
ESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPERYFDLNFDGDQEDFYPVLLVNSTGNGYDIAYVDTDLDYDFTDE
VPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGEYAVFGWDGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLY
GWDYTNVTTDTVQGVAPGAQIMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPESVAVDELTEK
YGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQALGYPDYYGFYYFPAYTNVRIAFFSSRGPRIDGE
IKPNVVAPGYGIYSSLPMWIGGADFMSGTSMATPHVSGVVALLISGAKAEGIYYNPDIIKKVLESGATWLEGDPYTGQKY
TELDQGHGLVNVTKSWEILKAINGTTLPIVDHWADKSYSDFAEYLGVDVIRGLYARNSIPDIVEWHIKYVGDTEYRTFEI
YATEPWIKPFVSGSVILENNTEFVLRVKYDVEGLEPGLYVGRIIIDDPTTPVIEDEILNTIVIPEKFTPENNYTLTWYDI
NGPEMVTHHFFTVPEGVDVLYAMTTYWDYGLYRPDGMFVFPYQLDYLPAAVSNPMPGNWELVWTGFNFAPLYESGFLVRI
YGVEITPSVWYINRTYLDTNTEFSIEFNITNIYAPINATLIPIGLGTYNASVESVGDGEFFIKGIEVPEGTAELKIRIGN
PSVPNSDLDLYLYDSKGNLVALDGNPTAEEEVVVEYPKPGVYSIVVHGYSVRDENGNPTTTTFDLVVQMTLDNGNIKLDK
DSIILGSNESVVVTANITIDRDHPTGVYSGIIEIRDNEVYQDTNTSIAKIPITLVIDKADFAVGLTPAEGVLGEARNYTL
IVKHALTLEPVPNATVIIGNYTYLTDENGTVTFTYAPTKLGSDEITVIVKKENFNTLEKTFQITVSEPEITEEDINEPKL
AMSSPEANATIVSVEMESEGGVKKTVTVEITINGTANETATIVVPVPKKAENIEVSGDHVISYSIEEGEYAKYVIITVKF
ASPVTVTVTYTIYAGPRVSILTLNFLGYSWYRLYSQKFDELYQKALELGVDNETLALALSYHEKAKEYYEKALELSEGNI
IQYLGDIRLLPPLRQAYINEMKAVKILEKAIEELEGEE

Specific function: Has endopeptidase activity toward caseins, casein fragments including alpha-S1-casein and synthetic peptides

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell envelope. Note=Cell envelope associated

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family

Homologues:

Organism=Homo sapiens, GI186972143, Length=845, Percent_Identity=25.3254437869822, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI4506775, Length=305, Percent_Identity=25.9016393442623, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533391, Length=556, Percent_Identity=25.5395683453237, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17137360, Length=711, Percent_Identity=26.5822784810127, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24653270, Length=711, Percent_Identity=26.5822784810127, Blast_Score=150, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PLS_PYRFU (P72186)

Other databases:

- EMBL:   U55835
- EMBL:   AE009950
- PIR:   T28159
- RefSeq:   NP_578016.1
- ProteinModelPortal:   P72186
- SMR:   P72186
- MEROPS:   S08.100
- EnsemblBacteria:   EBPYRT00000004688
- GeneID:   1468121
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0287
- NMPDR:   fig|186497.1.peg.292
- GeneTree:   EBGT00050000023056
- OMA:   NNARAEL
- ProtClustDB:   CLSK2393699
- GO:   GO:0031975
- GO:   GO:0006508
- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- Gene3D:   G3DSA:3.40.50.200
- PANTHER:   PTHR10795
- PRINTS:   PR00723

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC; SSF52743 Pept_S8_S53

EC number: NA

Molecular weight: Translated: 154476; Mature: 154476

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS00136 SUBTILASE_ASP; PS00137 SUBTILASE_HIS; PS00138 SUBTILASE_SER

Important sites: ACT_SITE 179-179 ACT_SITE 365-365 ACT_SITE 590-590

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKGLTVLFIAIMLLSVVPVHFVSAGTPPVSSENSTTSILPNQQVVTKEVSQAALNAIM
CCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
KGQPNMVLIIKTKEGKLEEAKTELEKLGAEILDENRVLNMLLVKIKPEKVKELNYISSLE
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHH
KAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINALQFIQEFGYDGSGVVVAVLDT
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC
GVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLN
CCCCCCCEEEECCCCCEEEEEEECCCCCCCEECCCCHHHHCCCEEEEEEEHHHHCCCEEC
ESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPERYFDLNFDGDQEDFYPVLLVNST
CCCCHHHHHHHHEEEECEEECCEECCCCEEEECCCCCCEEEECCCCCCCCCEEEEEEECC
GNGYDIAYVDTDLDYDFTDEVPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGEYAVFGW
CCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEECCCCCEEEEEE
DGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLYGWDYTNVTTDTVQGVAPGAQ
CCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCE
IMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPESVAVDELTEK
EEEEEEEECCCCCCHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCEEHHHHHHC
YGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQALGYPDYYGFYYFP
CCEEEEEEECCCCCCEEEEECCCCCEEEEEECEEEEEEEECEEEEHHCCCCCCCCEEEEE
AYTNVRIAFFSSRGPRIDGEIKPNVVAPGYGIYSSLPMWIGGADFMSGTSMATPHVSGVV
CCCEEEEEEEECCCCCCCCCCCCCEECCCCCHHHCCCCEECCHHHCCCCCCCCCCHHHHH
ALLISGAKAEGIYYNPDIIKKVLESGATWLEGDPYTGQKYTELDQGHGLVNVTKSWEILK
EEEECCCCCCCEEECHHHHHHHHHCCCCEECCCCCCCCCCCCHHCCCCEEEECCCCEEHH
AINGTTLPIVDHWADKSYSDFAEYLGVDVIRGLYARNSIPDIVEWHIKYVGDTEYRTFEI
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCEEEEEE
YATEPWIKPFVSGSVILENNTEFVLRVKYDVEGLEPGLYVGRIIIDDPTTPVIEDEILNT
EECCCCHHHHCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHCE
IVIPEKFTPENNYTLTWYDINGPEMVTHHFFTVPEGVDVLYAMTTYWDYGLYRPDGMFVF
EECCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEEHHHCCCEECCCCEEEE
PYQLDYLPAAVSNPMPGNWELVWTGFNFAPLYESGFLVRIYGVEITPSVWYINRTYLDTN
EEEECCCCHHHCCCCCCCEEEEEECCCCCEECCCCCEEEEEEEEECCEEEEEEEEEECCC
TEFSIEFNITNIYAPINATLIPIGLGTYNASVESVGDGEFFIKGIEVPEGTAELKIRIGN
CEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECC
PSVPNSDLDLYLYDSKGNLVALDGNPTAEEEVVVEYPKPGVYSIVVHGYSVRDENGNPTT
CCCCCCCEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCEEEEEEEEEEEECCCCCCCE
TTFDLVVQMTLDNGNIKLDKDSIILGSNESVVVTANITIDRDHPTGVYSGIIEIRDNEVY
EEEEEEEEEEECCCCEEECCCEEEECCCCCEEEEEEEEEECCCCCCCEEEEEEEECCEEE
QDTNTSIAKIPITLVIDKADFAVGLTPAEGVLGEARNYTLIVKHALTLEPVPNATVIIGN
ECCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEE
YTYLTDENGTVTFTYAPTKLGSDEITVIVKKENFNTLEKTFQITVSEPEITEEDINEPKL
EEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCE
AMSSPEANATIVSVEMESEGGVKKTVTVEITINGTANETATIVVPVPKKAENIEVSGDHV
EECCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCEEECCCEE
ISYSIEEGEYAKYVIITVKFASPVTVTVTYTIYAGPRVSILTLNFLGYSWYRLYSQKFDE
EEEEECCCCEEEEEEEEEEECCCEEEEEEEEEEECCEEEEEEEEECCHHHHHHHHHHHHH
LYQKALELGVDNETLALALSYHEKAKEYYEKALELSEGNIIQYLGDIRLLPPLRQAYINE
HHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCEECCCHHHHHHHHH
MKAVKILEKAIEELEGEE
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKGLTVLFIAIMLLSVVPVHFVSAGTPPVSSENSTTSILPNQQVVTKEVSQAALNAIM
CCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
KGQPNMVLIIKTKEGKLEEAKTELEKLGAEILDENRVLNMLLVKIKPEKVKELNYISSLE
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHH
KAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINALQFIQEFGYDGSGVVVAVLDT
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC
GVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLN
CCCCCCCEEEECCCCCEEEEEEECCCCCCCEECCCCHHHHCCCEEEEEEEHHHHCCCEEC
ESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPERYFDLNFDGDQEDFYPVLLVNST
CCCCHHHHHHHHEEEECEEECCEECCCCEEEECCCCCCEEEECCCCCCCCCEEEEEEECC
GNGYDIAYVDTDLDYDFTDEVPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGEYAVFGW
CCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEECCCCCEEEEEE
DGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLYGWDYTNVTTDTVQGVAPGAQ
CCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCE
IMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPESVAVDELTEK
EEEEEEEECCCCCCHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCEEHHHHHHC
YGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQALGYPDYYGFYYFP
CCEEEEEEECCCCCCEEEEECCCCCEEEEEECEEEEEEEECEEEEHHCCCCCCCCEEEEE
AYTNVRIAFFSSRGPRIDGEIKPNVVAPGYGIYSSLPMWIGGADFMSGTSMATPHVSGVV
CCCEEEEEEEECCCCCCCCCCCCCEECCCCCHHHCCCCEECCHHHCCCCCCCCCCHHHHH
ALLISGAKAEGIYYNPDIIKKVLESGATWLEGDPYTGQKYTELDQGHGLVNVTKSWEILK
EEEECCCCCCCEEECHHHHHHHHHCCCCEECCCCCCCCCCCCHHCCCCEEEECCCCEEHH
AINGTTLPIVDHWADKSYSDFAEYLGVDVIRGLYARNSIPDIVEWHIKYVGDTEYRTFEI
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCEEEEEE
YATEPWIKPFVSGSVILENNTEFVLRVKYDVEGLEPGLYVGRIIIDDPTTPVIEDEILNT
EECCCCHHHHCCCEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHCE
IVIPEKFTPENNYTLTWYDINGPEMVTHHFFTVPEGVDVLYAMTTYWDYGLYRPDGMFVF
EECCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEEHHHCCCEECCCCEEEE
PYQLDYLPAAVSNPMPGNWELVWTGFNFAPLYESGFLVRIYGVEITPSVWYINRTYLDTN
EEEECCCCHHHCCCCCCCEEEEEECCCCCEECCCCCEEEEEEEEECCEEEEEEEEEECCC
TEFSIEFNITNIYAPINATLIPIGLGTYNASVESVGDGEFFIKGIEVPEGTAELKIRIGN
CEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECC
PSVPNSDLDLYLYDSKGNLVALDGNPTAEEEVVVEYPKPGVYSIVVHGYSVRDENGNPTT
CCCCCCCEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCEEEEEEEEEEEECCCCCCCE
TTFDLVVQMTLDNGNIKLDKDSIILGSNESVVVTANITIDRDHPTGVYSGIIEIRDNEVY
EEEEEEEEEEECCCCEEECCCEEEECCCCCEEEEEEEEEECCCCCCCEEEEEEEECCEEE
QDTNTSIAKIPITLVIDKADFAVGLTPAEGVLGEARNYTLIVKHALTLEPVPNATVIIGN
ECCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEE
YTYLTDENGTVTFTYAPTKLGSDEITVIVKKENFNTLEKTFQITVSEPEITEEDINEPKL
EEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCE
AMSSPEANATIVSVEMESEGGVKKTVTVEITINGTANETATIVVPVPKKAENIEVSGDHV
EECCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCEEECCCEE
ISYSIEEGEYAKYVIITVKFASPVTVTVTYTIYAGPRVSILTLNFLGYSWYRLYSQKFDE
EEEEECCCCEEEEEEEEEEECCCEEEEEEEEEEECCEEEEEEEEECCHHHHHHHHHHHHH
LYQKALELGVDNETLALALSYHEKAKEYYEKALELSEGNIIQYLGDIRLLPPLRQAYINE
HHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCEECCCHHHHHHHHH
MKAVKILEKAIEELEGEE
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8702780; 11210516