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The map label for this gene is gltB [C]

Identifier: 18976577

GI number: 18976577

Start: 220424

End: 221932

Strand: Direct

Name: gltB [C]

Synonym: PF0205

Alternate gene names: 18976577

Gene position: 220424-221932 (Clockwise)

Preceding gene: 18976576

Following gene: 18976578

Centisome position: 11.55

GC content: 41.42

Gene sequence:

>1509_bases
ATGAGAACCCATGTTCTCCCAGAATTTCTGGTTGAAAGAGATGACAAGAGGTGTATAAAGTGTGGTGCGTGTATATACCA
ATGCCCCTTTGGAGTTTACAAATGGAATGCTGATAAAAGTGATATTACAATTGACTATACAAAGTGTGTTGGTTGTCAAA
GATGCGTTGTGTTCTGTCCCACAGATGCTTTAATTGTGAGACCTTATCCGGGCTCTTATAAACCCAATGCGTATTGGAAT
AGAGAGGTTATATCTGATATAAAGAGACAGGCTGAGGGAGGAGGAGTTTTATTAACTGGGACAGGTAATGATAAACCTTA
CAAAGTCTATTTTGACCACATACTTCTTAATGCTTCTCAAGTTACCAATCCTCCTATAGATCCGCTAAGAGAACCTATTG
AACTCAGAACGTTTATTGGGGGCAAGCCAGAAAAATTAGAAGTGGATTTAGAAAATATCGAGATAAAAACAGAAATTCCT
CCTAACATAGAAATAGAGGTTCCAATTATGTTTGCAGGCATGAGCTACGGTGCTTTAAGCTACAACGCTTTTCTTGCAAT
AGCTATGGCTGCTAAGGAATTTGGAACTATGTTTAGTACAGGAGAAGGTGGTTTGCCCAGGGAGCTTAGGAGGAAATATG
GTGATCATGCAATAGTTCAAGTTGCAAGTGGAAGGTTTGGGGTTGATCCTGATTACCTAAATTCGGCTGCAGCAATTGAG
ATAAAAATTGGCCAGGGAGCAAAGCCAGGAATAGGTGGTCATCTTCCTGGGGAAAAAGTTACAGAAGGAATAGCTAGAAC
ACGTATGATACCTCCTGGGACTGATGCAATATCTCCAGCTCCCCATCATGATATATACTCAATTGAAGACTTAGCTACGT
TGATACACGCAATAAAAGAAGCAACAAATTATGAAAAGCCGGTATTTGTTAAAGTTGCTGCAGTTCACAATATAGCAGCA
ATAGCAAGTGGAATAGCAAGGGCTGGAGCTGATGCGATAGTTATAGATGGATTTAGAGGAGGCACTGGGGCGGCACCAAA
GAGAATTAGAGACAACGTTGGGATACCAATTGAGCTGGCCTTAGCTTCCGTGGATAGGAGATTGAGAGAGGAAGGAATTA
GGAATAGGGTATCGTTAATAGTTTCTGGGGGAATTAGAAACGCTGCCGACGTTGTCAAAGCTATAGCACTTGGAGCGGAT
GCAGTGTACATTGGAACTGCAGCTTTGATTGCAATCGGATGTACAATGTGTCAGAAGTGCTATACGGGGAAATGTCCTTG
GGGAATAACAACTCAAGATCCTATTCTTTCGAGAAGATTGGATCCAAATGAGGCCTCAAAGAGACTAATTAATCTTTTGA
AGGCCTGGAGTTTGGAAATAAAAGAAATGCTTGGGGCTATGGGCATAAATGCCATAGAAAGTTTGAGAGGAAATAGGGAA
CATCTAAGAGGAATTGGGTTGGAGAAATGGGAGCTTGAAGTATTAGGAATTAAGGGGGCGGGAGAATGA

Upstream 100 bases:

>100_bases
ATCTGTTTAGAGATGTTGACAGGATTTACACTCCCTATGGAGGTGAACTAGTAGTAGGTAAGCTAGAGGAAGACATTAAA
AAATTTGTGGGGGAGAGCCA

Downstream 100 bases:

>100_bases
GCACGGCCGAAGTTTTGAACCCTTATATATTTGGAGTTAGACCTATAGAGGTTCTTAAAAGACAGGTAAAGGTTGAAGGA
GAAAGAGCAACTATTGATGC

Product: glutamate synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MRTHVLPEFLVERDDKRCIKCGACIYQCPFGVYKWNADKSDITIDYTKCVGCQRCVVFCPTDALIVRPYPGSYKPNAYWN
REVISDIKRQAEGGGVLLTGTGNDKPYKVYFDHILLNASQVTNPPIDPLREPIELRTFIGGKPEKLEVDLENIEIKTEIP
PNIEIEVPIMFAGMSYGALSYNAFLAIAMAAKEFGTMFSTGEGGLPRELRRKYGDHAIVQVASGRFGVDPDYLNSAAAIE
IKIGQGAKPGIGGHLPGEKVTEGIARTRMIPPGTDAISPAPHHDIYSIEDLATLIHAIKEATNYEKPVFVKVAAVHNIAA
IASGIARAGADAIVIDGFRGGTGAAPKRIRDNVGIPIELALASVDRRLREEGIRNRVSLIVSGGIRNAADVVKAIALGAD
AVYIGTAALIAIGCTMCQKCYTGKCPWGITTQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLRGNRE
HLRGIGLEKWELEVLGIKGAGE

Sequences:

>Translated_502_residues
MRTHVLPEFLVERDDKRCIKCGACIYQCPFGVYKWNADKSDITIDYTKCVGCQRCVVFCPTDALIVRPYPGSYKPNAYWN
REVISDIKRQAEGGGVLLTGTGNDKPYKVYFDHILLNASQVTNPPIDPLREPIELRTFIGGKPEKLEVDLENIEIKTEIP
PNIEIEVPIMFAGMSYGALSYNAFLAIAMAAKEFGTMFSTGEGGLPRELRRKYGDHAIVQVASGRFGVDPDYLNSAAAIE
IKIGQGAKPGIGGHLPGEKVTEGIARTRMIPPGTDAISPAPHHDIYSIEDLATLIHAIKEATNYEKPVFVKVAAVHNIAA
IASGIARAGADAIVIDGFRGGTGAAPKRIRDNVGIPIELALASVDRRLREEGIRNRVSLIVSGGIRNAADVVKAIALGAD
AVYIGTAALIAIGCTMCQKCYTGKCPWGITTQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLRGNRE
HLRGIGLEKWELEVLGIKGAGE
>Mature_502_residues
MRTHVLPEFLVERDDKRCIKCGACIYQCPFGVYKWNADKSDITIDYTKCVGCQRCVVFCPTDALIVRPYPGSYKPNAYWN
REVISDIKRQAEGGGVLLTGTGNDKPYKVYFDHILLNASQVTNPPIDPLREPIELRTFIGGKPEKLEVDLENIEIKTEIP
PNIEIEVPIMFAGMSYGALSYNAFLAIAMAAKEFGTMFSTGEGGLPRELRRKYGDHAIVQVASGRFGVDPDYLNSAAAIE
IKIGQGAKPGIGGHLPGEKVTEGIARTRMIPPGTDAISPAPHHDIYSIEDLATLIHAIKEATNYEKPVFVKVAAVHNIAA
IASGIARAGADAIVIDGFRGGTGAAPKRIRDNVGIPIELALASVDRRLREEGIRNRVSLIVSGGIRNAADVVKAIALGAD
AVYIGTAALIAIGCTMCQKCYTGKCPWGITTQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLRGNRE
HLRGIGLEKWELEVLGIKGAGE

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=357, Percent_Identity=37.2549019607843, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17570289, Length=360, Percent_Identity=39.1666666666667, Blast_Score=231, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6320030, Length=345, Percent_Identity=39.1304347826087, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28574881, Length=345, Percent_Identity=40.5797101449275, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24665539, Length=345, Percent_Identity=40.5797101449275, Blast_Score=218, Evalue=9e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013785
- InterPro:   IPR002932 [H]

Pfam domain/function: PF01645 Glu_synthase [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 54458; Mature: 54458

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHVLPEFLVERDDKRCIKCGACIYQCPFGVYKWNADKSDITIDYTKCVGCQRCVVFCP
CCCCCCHHHHHCCCCHHHHHHCCHHHHCCCCEEEECCCCCCEEEEHHHHCCCCEEEEECC
TDALIVRPYPGSYKPNAYWNREVISDIKRQAEGGGVLLTGTGNDKPYKVYFDHILLNASQ
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEHHHEEHHH
VTNPPIDPLREPIELRTFIGGKPEKLEVDLENIEIKTEIPPNIEIEVPIMFAGMSYGALS
CCCCCHHHHHCCHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCH
YNAFLAIAMAAKEFGTMFSTGEGGLPRELRRKYGDHAIVQVASGRFGVDPDYLNSAAAIE
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHCCCCEEEE
IKIGQGAKPGIGGHLPGEKVTEGIARTRMIPPGTDAISPAPHHDIYSIEDLATLIHAIKE
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ATNYEKPVFVKVAAVHNIAAIASGIARAGADAIVIDGFRGGTGAAPKRIRDNVGIPIELA
HCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHCCCCCCHHHH
LASVDRRLREEGIRNRVSLIVSGGIRNAADVVKAIALGADAVYIGTAALIAIGCTMCQKC
HHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YTGKCPWGITTQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLRGNRE
CCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHH
HLRGIGLEKWELEVLGIKGAGE
HHHCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MRTHVLPEFLVERDDKRCIKCGACIYQCPFGVYKWNADKSDITIDYTKCVGCQRCVVFCP
CCCCCCHHHHHCCCCHHHHHHCCHHHHCCCCEEEECCCCCCEEEEHHHHCCCCEEEEECC
TDALIVRPYPGSYKPNAYWNREVISDIKRQAEGGGVLLTGTGNDKPYKVYFDHILLNASQ
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEHHHEEHHH
VTNPPIDPLREPIELRTFIGGKPEKLEVDLENIEIKTEIPPNIEIEVPIMFAGMSYGALS
CCCCCHHHHHCCHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCH
YNAFLAIAMAAKEFGTMFSTGEGGLPRELRRKYGDHAIVQVASGRFGVDPDYLNSAAAIE
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHCCCCEEEE
IKIGQGAKPGIGGHLPGEKVTEGIARTRMIPPGTDAISPAPHHDIYSIEDLATLIHAIKE
EEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ATNYEKPVFVKVAAVHNIAAIASGIARAGADAIVIDGFRGGTGAAPKRIRDNVGIPIELA
HCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHCCCCCCHHHH
LASVDRRLREEGIRNRVSLIVSGGIRNAADVVKAIALGADAVYIGTAALIAIGCTMCQKC
HHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YTGKCPWGITTQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLRGNRE
CCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHH
HLRGIGLEKWELEVLGIKGAGE
HHHCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]