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The map label for this gene is csd [H]

Identifier: 18976536

GI number: 18976536

Start: 174556

End: 175761

Strand: Direct

Name: csd [H]

Synonym: PF0164

Alternate gene names: 18976536

Gene position: 174556-175761 (Clockwise)

Preceding gene: 18976534

Following gene: 18976540

Centisome position: 9.15

GC content: 42.37

Gene sequence:

>1206_bases
ATGAAGATTCCCGACGATGTTAGAAAGGATATTCCCTTGACCCAGGAAGTGATATATTTTGACAACACTGCCACCTCTCT
AACTCCAAAACCAGTTATTGAAGCGATGGATGAATATTACTTAAAATATAGGGCTAACGTTCATCGTGGAGTACATAGGC
TTTCCCAGATGGCTACCCAGAAATATGAGGAGTCAAGAAAGGTTGTTGCTGATTTCATAAATGCGAAGTTTGAGGAGATT
GTTTTTACAAAAAATACGAGCGAAAGTTTAAACTTGGTGGCCCTGGGACTTGAGCATACCTTCAAAAAAGGGGACAAAAT
CGTGACTACACCCTATGAGCACCACTCAAACCTCTTACCGTGGCAAAGGTTAGCAAAAAAGTTGGGATTGAAGCTTGAGT
TCATAGAGGGAGATGATGAGGGTAACTTGGACTTAAGCGATGCGGAAAAGAAAATTAAAGGGGCCAAGCTAGTAGCAGTG
CAACATGTTTCAAATGCCCTAGGTGTTATCCATGAAGTTGAAGAACTTGGAAGAATGGCAAAGGAGGAGGGGGCTATATT
TGTTGTAGACGCGGCACAAAGTGTTGGACACATGGAAGTTGACGTTAAGAAGCTTAATGCAGATTTTCTAGCATTTTCAG
GACACAAGGGGCCAATGGGGCCTACTGGAATTGGGGTTCTTTTTATAAGTGAAGAGTACTTCGATGTCTTTGACCCTCCA
TTGATAGGAGGAGGAACGATAGAGGACGTTGACCTCTGCTGTTATAAGTTGACTGAGCCCCCGGAGAGATTTGAAGCAGG
TACTCCAAACATTGGTGGAGCAATAGGATTGGCTGCGGGGATAAAGTACATAGAAAAGATTGGAATTGAGAAAATAGAGA
AGCAGGAAAGAAAGCTAGTAAAGAGAACCACAGAAGGGTTAGATGAGCTCGAAATTCCATGGTATGGACCTAGGAATCTA
GACAAACATGCAGGAGTTGTGAGCTTTAATGTTCCTCCTCTCCATCCCCACGATGTTGCTGCAGTTCTTGACGAGCATAA
AATTATGGTTAGAAGTGGCCATCACTGTGCTCTTCCAGTAATGAAGAAGCTTGGAATAAATGGGACTGTTAGAGCATCGT
TCCACGTCTATAATTCAGTAGAAGAAGTAGAAATTTTCCTTGGGGTGCTTGAAGATTTAGTCAGAAAAATTAGAGGAGCT
CTTTAA

Upstream 100 bases:

>100_bases
CATTTTTAAAATGTTTTGTTCCATTTTCAGAACAAAAATTCCACATAATTGTCCAGAAACGATTATTAAATTTGATGAAA
ATTTTTTCAAGGTGGTTAGC

Downstream 100 bases:

>100_bases
AGATCTCAGGAAGTGATTTTATATTTGGAATCTCGTATCCTCTCTCCTCTAACTTCTTGATTTCTTTTCCTTCTGTGTTT
ATCCACACTGCGGCCATGCC

Product: nifS protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKIPDDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLKYRANVHRGVHRLSQMATQKYEESRKVVADFINAKFEEI
VFTKNTSESLNLVALGLEHTFKKGDKIVTTPYEHHSNLLPWQRLAKKLGLKLEFIEGDDEGNLDLSDAEKKIKGAKLVAV
QHVSNALGVIHEVEELGRMAKEEGAIFVVDAAQSVGHMEVDVKKLNADFLAFSGHKGPMGPTGIGVLFISEEYFDVFDPP
LIGGGTIEDVDLCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIEKIEKQERKLVKRTTEGLDELEIPWYGPRNL
DKHAGVVSFNVPPLHPHDVAAVLDEHKIMVRSGHHCALPVMKKLGINGTVRASFHVYNSVEEVEIFLGVLEDLVRKIRGA
L

Sequences:

>Translated_401_residues
MKIPDDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLKYRANVHRGVHRLSQMATQKYEESRKVVADFINAKFEEI
VFTKNTSESLNLVALGLEHTFKKGDKIVTTPYEHHSNLLPWQRLAKKLGLKLEFIEGDDEGNLDLSDAEKKIKGAKLVAV
QHVSNALGVIHEVEELGRMAKEEGAIFVVDAAQSVGHMEVDVKKLNADFLAFSGHKGPMGPTGIGVLFISEEYFDVFDPP
LIGGGTIEDVDLCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIEKIEKQERKLVKRTTEGLDELEIPWYGPRNL
DKHAGVVSFNVPPLHPHDVAAVLDEHKIMVRSGHHCALPVMKKLGINGTVRASFHVYNSVEEVEIFLGVLEDLVRKIRGA
L
>Mature_401_residues
MKIPDDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLKYRANVHRGVHRLSQMATQKYEESRKVVADFINAKFEEI
VFTKNTSESLNLVALGLEHTFKKGDKIVTTPYEHHSNLLPWQRLAKKLGLKLEFIEGDDEGNLDLSDAEKKIKGAKLVAV
QHVSNALGVIHEVEELGRMAKEEGAIFVVDAAQSVGHMEVDVKKLNADFLAFSGHKGPMGPTGIGVLFISEEYFDVFDPP
LIGGGTIEDVDLCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIEKIEKQERKLVKRTTEGLDELEIPWYGPRNL
DKHAGVVSFNVPPLHPHDVAAVLDEHKIMVRSGHHCALPVMKKLGINGTVRASFHVYNSVEEVEIFLGVLEDLVRKIRGA
L

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=213, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI156713448, Length=261, Percent_Identity=28.3524904214559, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787970, Length=402, Percent_Identity=39.8009950248756, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1789175, Length=393, Percent_Identity=32.824427480916, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI48994898, Length=401, Percent_Identity=27.1820448877805, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25143064, Length=237, Percent_Identity=29.535864978903, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=387, Percent_Identity=26.6149870801034, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147498, Length=388, Percent_Identity=24.2268041237113, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=34.4978165938865, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI20129463, Length=229, Percent_Identity=30.5676855895196, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44609; Mature: 44609

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPDDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLKYRANVHRGVHRLSQMATQ
CCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYEESRKVVADFINAKFEEIVFTKNTSESLNLVALGLEHTFKKGDKIVTTPYEHHSNLLP
HHHHHHHHHHHHHCCHHHHEEEECCCCCCCEEEEECHHHHHHCCCEEEECCHHHCCCCCC
WQRLAKKLGLKLEFIEGDDEGNLDLSDAEKKIKGAKLVAVQHVSNALGVIHEVEELGRMA
HHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
KEEGAIFVVDAAQSVGHMEVDVKKLNADFLAFSGHKGPMGPTGIGVLFISEEYFDVFDPP
HHCCCEEEEECCCCCCCEEEEHHHHCCCEEEECCCCCCCCCCCEEEEEEECHHHHHCCCC
LIGGGTIEDVDLCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIEKIEKQERKLV
CCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KRTTEGLDELEIPWYGPRNLDKHAGVVSFNVPPLHPHDVAAVLDEHKIMVRSGHHCALPV
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHH
MKKLGINGTVRASFHVYNSVEEVEIFLGVLEDLVRKIRGAL
HHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPDDVRKDIPLTQEVIYFDNTATSLTPKPVIEAMDEYYLKYRANVHRGVHRLSQMATQ
CCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYEESRKVVADFINAKFEEIVFTKNTSESLNLVALGLEHTFKKGDKIVTTPYEHHSNLLP
HHHHHHHHHHHHHCCHHHHEEEECCCCCCCEEEEECHHHHHHCCCEEEECCHHHCCCCCC
WQRLAKKLGLKLEFIEGDDEGNLDLSDAEKKIKGAKLVAVQHVSNALGVIHEVEELGRMA
HHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
KEEGAIFVVDAAQSVGHMEVDVKKLNADFLAFSGHKGPMGPTGIGVLFISEEYFDVFDPP
HHCCCEEEEECCCCCCCEEEEHHHHCCCEEEECCCCCCCCCCCEEEEEEECHHHHHCCCC
LIGGGTIEDVDLCCYKLTEPPERFEAGTPNIGGAIGLAAGIKYIEKIGIEKIEKQERKLV
CCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KRTTEGLDELEIPWYGPRNLDKHAGVVSFNVPPLHPHDVAAVLDEHKIMVRSGHHCALPV
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHH
MKKLGINGTVRASFHVYNSVEEVEIFLGVLEDLVRKIRGAL
HHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]