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The map label for this gene is 18976484

Identifier: 18976484

GI number: 18976484

Start: 117115

End: 118179

Strand: Direct

Name: 18976484

Synonym: PF0112

Alternate gene names: NA

Gene position: 117115-118179 (Clockwise)

Preceding gene: 18976480

Following gene: 18976485

Centisome position: 6.14

GC content: 38.12

Gene sequence:

>1065_bases
ATGGAAGTTAACAAAGCATCTTTAACTTATGACGTCCCAGAGGATAGGGAATATGCTACAAAGAGGATACTTTCCCTCAA
AAGGCCTTCAAAAATTATGGTAATCGGAGATGTCGATACTGGGAAGACGACACTCATTGTCTATTTGGCAAATGAGCTTA
TATCGAGAGGATTTAAAGTTGCAATAGTCGATGCTGATGTTGGTCAGAAAGGCATTCTTCCCCCAGCCACAATAAGCTTA
GCTCTCGCTGACATGAAATTTTCCTCTCTAAGTGAGTTGAAACCCTTAATTCACTATTTTGTAGGTTCTATAACTCCTTC
CCAGTTTTTTGGAGAGATGATTGTTGGAACTATGCGCTTGAGTGAGATTGGGAAAAAATTTGCTGATTATGTGCTAATAG
ATACAACTGGGATGATATATGGCTCAGGAGTGGAATTGAAGAGATTGAAGATAGAGGCCGTTAAACCAGATTTAATACTT
GCCTTAGAGAAGAAAGAAGAGCTAAATCCCATTGTTTCAGGATTTGAGGACAAAACGATAAAACTAAAGGTTAGTGAAAA
TGCTAGGAGTTATTCTAGAAGTGAAAGAAGGCAAATTAGGCAAGAAAAATGGAGAAAGTATTTTGAAAATGCAAAAATCG
TTAGTTTTTCTCTGGAGAATGTTGTTGTTACGGGAACATCATTATTTCAGGGGAGTGATATAAGAGAAGAGGAAAAATCC
CTTTTGGAAAGGCTCTTTAAATGGGTAATTCTTCATGGAAGAAGGATAGGGGATAAGTATTTTGTGGTTAAAGCAGATGT
TGCGGAAGTGCCTAGGGTAGTGGACAAAAATGTTGTTAGGTACTTTGACTTTGAAAAGCTTAGCAATCTCCTTGTAGGTT
TACTAAACGAGGAGGGCTTATGCCTAGGAGTAGGAATTATTAAAGGCATAAACTTTGGGGAAAAAAGGATAGATATCTTG
ACTCCAGTCTCTGAAATTGAGAATGTCAGGGAAATAAGGTTTGGTAGGATTAGGGTAAGGGAAGATGGTGAAGAGTTGGG
AATACTGGATAGGGAAGCACTTTAA

Upstream 100 bases:

>100_bases
TCCGAATTCTTTTAGTAGTTCTTTGGCCTTCTCACTAAATGGGTCTAGCATGTTTGATAAAATAAATGAACCCCGATATA
ACTTTAATGGAGGTGGGAGA

Downstream 100 bases:

>100_bases
CAAAAAGGTTTATGAAACCTGTAAAGTAAAATGTTATTGAAAATCAAGATGGAGGTAGGCATATGCCAAGGGAGAACGTT
GAGCTAACTAACAGACAGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Polynucleotide kinase PF0112

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKVAIVDADVGQKGILPPATISL
ALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRLSEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLIL
ALEKKEELNPIVSGFEDKTIKLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKS
LLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGLCLGVGIIKGINFGEKRIDIL
TPVSEIENVREIRFGRIRVREDGEELGILDREAL

Sequences:

>Translated_354_residues
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKVAIVDADVGQKGILPPATISL
ALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRLSEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLIL
ALEKKEELNPIVSGFEDKTIKLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKS
LLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGLCLGVGIIKGINFGEKRIDIL
TPVSEIENVREIRFGRIRVREDGEELGILDREAL
>Mature_354_residues
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKVAIVDADVGQKGILPPATISL
ALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRLSEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLIL
ALEKKEELNPIVSGFEDKTIKLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKS
LLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGLCLGVGIIKGINFGEKRIDIL
TPVSEIENVREIRFGRIRVREDGEELGILDREAL

Specific function: Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA

COG id: COG1341

COG function: function code R; Predicted GTPase or GTP-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRNK_PYRFU (Q8U4H6)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_577841.1
- ProteinModelPortal:   Q8U4H6
- EnsemblBacteria:   EBPYRT00000005826
- GeneID:   1467941
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0112
- NMPDR:   fig|186497.1.peg.112
- GeneTree:   EBGT00050000023291
- HOGENOM:   HBG538965
- OMA:   NDLGPPT
- ProtClustDB:   CLSK544691
- InterPro:   IPR010655

Pfam domain/function: PF06807 Clp1

EC number: =2.7.1.78

Molecular weight: Translated: 40054; Mature: 40054

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKV
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEHHHHHHCCCEE
AIVDADVGQKGILPPATISLALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRL
EEEECCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLILALEKKEELNPIVSGFEDKTI
HHHHHHHHCEEEEEECCEEEECCCEEEEEEEEEECCCEEEEECCHHHCCHHHCCCCCCEE
KLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKS
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCEECCCCCCHHHHH
LLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGL
HHHHHHHHHHHCCCEECCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
CLGVGIIKGINFGEKRIDILTPVSEIENVREIRFGRIRVREDGEELGILDREAL
EEEEHHHHCCCCCCHHEEEECCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKV
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEHHHHHHCCCEE
AIVDADVGQKGILPPATISLALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRL
EEEECCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLILALEKKEELNPIVSGFEDKTI
HHHHHHHHCEEEEEECCEEEECCCEEEEEEEEEECCCEEEEECCHHHCCHHHCCCCCCEE
KLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKS
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCEECCCCCCHHHHH
LLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGL
HHHHHHHHHHHCCCEECCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
CLGVGIIKGINFGEKRIDILTPVSEIENVREIRFGRIRVREDGEELGILDREAL
EEEEHHHHCCCCCCHHEEEECCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA