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The map label for this gene is queC

Identifier: 18976420

GI number: 18976420

Start: 55848

End: 56570

Strand: Direct

Name: queC

Synonym: PF0048

Alternate gene names: 18976420

Gene position: 55848-56570 (Clockwise)

Preceding gene: 18976408

Following gene: 18976429

Centisome position: 2.93

GC content: 42.19

Gene sequence:

>723_bases
ATGAAACGAAGAGCAGTTGTTCTGTTTTCTGGAGGATTGGATAGTACAGCATGCCTGTACTGGGCTAAAAAGCAGTATGA
TGAGGTCATTATGCTCACCGTAAACTATGGAAGCAACGAGGAAAGAGTTACAAACAAGGTAGCGGAGTACTTCTCAAAAG
AGTTAGACGTAAGGTTAAAAATTGTTAAGCTGGATTTTTTGAAGGAATTCTCGGAAATAAGGGGTAGCTCTCTTGTGGGT
GGAGAAGTTCCAAGAGTAACTGCAGAAGAGCTGGAGGATATTGAGAAAGCGAGCGAAACGGCAAGAAGTGTCTGGATTCC
AGCAAGAAATCTTGTTTTAATAAGTGTTGCTGCATCTCTCCTGGATGCCTTGGGTGGGGGAGATATAATTGTAGGGTTCA
ATGCTGAGGAAGCTACAACATTTCCAGACAACTCGAGAGAATTCGTGGAAAAGTTAAACGAGGCTCTAAGGTTTGCAACC
CTAAATCCGGTAAAAGTTGTTGCCCCTCTAATAGATTTGGACAAGAGGGGAATTGCAAAGTTGCTTAAAGAGCTAAATGC
GAAGTATGAGTACTCAAACTCCTGTTATAACCCAAAGGGTTTCACTGAAGATGGAAGGCCAATTCACTGTGGAGAATGTG
AGAGTTGTGTGAGAAGGCATAAGGGTCTTATTGAGGGGATTGGAGAAGATAAAACAGTTTATGCAATTACTCCCAGGATA
TAG

Upstream 100 bases:

>100_bases
AATAATAACTATGGCAATAAGAACTACTTTCGTTAGCTTGTCCATTTACTACCCCCTATATGGAAAAAGCATAAAAAGAT
ATTAAAACTTAATCATTGCC

Downstream 100 bases:

>100_bases
TCCTAAGCAAGAATTCTGCAATACTCCTTGCCAGTGGTGGTGGGACAGCTTCTCCTACGCTATCGAACTGTATGTTCCTA
CCACCGAGGAATACAAAATC

Product: succinoglycan biosynthesis regulator

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKRRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERVTNKVAEYFSKELDVRLKIVKLDFLKEFSEIRGSSLVG
GEVPRVTAEELEDIEKASETARSVWIPARNLVLISVAASLLDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFAT
LNPVKVVAPLIDLDKRGIAKLLKELNAKYEYSNSCYNPKGFTEDGRPIHCGECESCVRRHKGLIEGIGEDKTVYAITPRI

Sequences:

>Translated_240_residues
MKRRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERVTNKVAEYFSKELDVRLKIVKLDFLKEFSEIRGSSLVG
GEVPRVTAEELEDIEKASETARSVWIPARNLVLISVAASLLDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFAT
LNPVKVVAPLIDLDKRGIAKLLKELNAKYEYSNSCYNPKGFTEDGRPIHCGECESCVRRHKGLIEGIGEDKTVYAITPRI
>Mature_240_residues
MKRRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERVTNKVAEYFSKELDVRLKIVKLDFLKEFSEIRGSSLVG
GEVPRVTAEELEDIEKASETARSVWIPARNLVLISVAASLLDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFAT
LNPVKVVAPLIDLDKRGIAKLLKELNAKYEYSNSCYNPKGFTEDGRPIHCGECESCVRRHKGLIEGIGEDKTVYAITPRI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=237, Percent_Identity=31.2236286919831, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PYRFU (Q8U4N3)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_577777.1
- ProteinModelPortal:   Q8U4N3
- SMR:   Q8U4N3
- EnsemblBacteria:   EBPYRT00000005267
- GeneID:   1467877
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0048
- NMPDR:   fig|186497.1.peg.48
- GeneTree:   EBGT00050000022288
- HOGENOM:   HBG553284
- OMA:   ETARSVW
- ProtClustDB:   CLSK253111
- HAMAP:   MF_01633_A
- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26726; Mature: 26726

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERVTNKVAEYFSKELDVRLK
CCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
IVKLDFLKEFSEIRGSSLVGGEVPRVTAEELEDIEKASETARSVWIPARNLVLISVAASL
EEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
LDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFATLNPVKVVAPLIDLDKRGIAK
HHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LLKELNAKYEYSNSCYNPKGFTEDGRPIHCGECESCVRRHKGLIEGIGEDKTVYAITPRI
HHHHHCCCEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure
MKRRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERVTNKVAEYFSKELDVRLK
CCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
IVKLDFLKEFSEIRGSSLVGGEVPRVTAEELEDIEKASETARSVWIPARNLVLISVAASL
EEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
LDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFATLNPVKVVAPLIDLDKRGIAK
HHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LLKELNAKYEYSNSCYNPKGFTEDGRPIHCGECESCVRRHKGLIEGIGEDKTVYAITPRI
HHHHHCCCEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA