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The map label for this gene is glmU [H]

Identifier: 189424568

GI number: 189424568

Start: 1579401

End: 1580045

Strand: Reverse

Name: glmU [H]

Synonym: Glov_1509

Alternate gene names: 189424568

Gene position: 1580045-1579401 (Counterclockwise)

Preceding gene: 189424569

Following gene: 189424567

Centisome position: 40.33

GC content: 55.19

Gene sequence:

>645_bases
ATGTCTGAATTCTTTGCCCACCAATCATCCTATATCGACGAAGGTGCAGAAATTGGTGCAGGCACCAAGATCTGGCACTT
CAGCCACATTATGAGCGGAGCAACCATTGGTGAACGCTGCAGCTTTGGCCAGAACTGTGTGGTATCGCCCGGTGTGGTAA
TCGGTTCCAATGTCAAGGTCCAGAACAACGTCTCCATCTATGAGGGCACGGTGATTGAAGACGATGTTTTCCTTGGCCCC
TCCTGCGTCTTGACCAATGTCACCAACCCCCGCTCCCAGGTGGTGCGGCGTAGCCTGTATGAGACAACCCTGCTGCGGCG
GGGCTGTTCCATCGGAGCGAACGCAACCATCGTGTGTGGCATCACCATAGGTCGCTATGCCTTTGTCGCTGCCGGTGCGG
TGGTTGCCAAAGATGTTCCCGATTACGCACTGATGGTTGGAGTGCCTGCCCGTCAGAAAGGCTGGATGAGCCGCCACGGA
CTGCCGCTTACTCCCGGCCCCGATGGCATCATGGTCTGCAAAGAAAGCGGTTACTGCTATCAGGAGGTGCAGCCGGGACT
GCTTAAATGCCTGGACCTCGATGAAGATGCACCACTACCATCAGAAAAAGCGGTTGGCAGCGTCTGCTATGATGACCTGA
AATAA

Upstream 100 bases:

>100_bases
CCGTCCGGCCATCGAACTGGCTCATGCCATCCGCAATGTCTCTGCGTCAGGTATATCTTCTGACTCACATCCATTTCTCC
AGCATAGTGTGAGGTAGCCC

Downstream 100 bases:

>100_bases
ACCCAAAAACGGCATTTACTCACGCAAAGACGCCAAGTATGAATAAAAGTCAGAATCTTATAAAAAACAGTCTACGTCTT
TCGGGTAATGATCTGATCTT

Product: transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSEFFAHQSSYIDEGAEIGAGTKIWHFSHIMSGATIGERCSFGQNCVVSPGVVIGSNVKVQNNVSIYEGTVIEDDVFLGP
SCVLTNVTNPRSQVVRRSLYETTLLRRGCSIGANATIVCGITIGRYAFVAAGAVVAKDVPDYALMVGVPARQKGWMSRHG
LPLTPGPDGIMVCKESGYCYQEVQPGLLKCLDLDEDAPLPSEKAVGSVCYDDLK

Sequences:

>Translated_214_residues
MSEFFAHQSSYIDEGAEIGAGTKIWHFSHIMSGATIGERCSFGQNCVVSPGVVIGSNVKVQNNVSIYEGTVIEDDVFLGP
SCVLTNVTNPRSQVVRRSLYETTLLRRGCSIGANATIVCGITIGRYAFVAAGAVVAKDVPDYALMVGVPARQKGWMSRHG
LPLTPGPDGIMVCKESGYCYQEVQPGLLKCLDLDEDAPLPSEKAVGSVCYDDLK
>Mature_213_residues
SEFFAHQSSYIDEGAEIGAGTKIWHFSHIMSGATIGERCSFGQNCVVSPGVVIGSNVKVQNNVSIYEGTVIEDDVFLGPS
CVLTNVTNPRSQVVRRSLYETTLLRRGCSIGANATIVCGITIGRYAFVAAGAVVAKDVPDYALMVGVPARQKGWMSRHGL
PLTPGPDGIMVCKESGYCYQEVQPGLLKCLDLDEDAPLPSEKAVGSVCYDDLK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 22897; Mature: 22766

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFFAHQSSYIDEGAEIGAGTKIWHFSHIMSGATIGERCSFGQNCVVSPGVVIGSNVKV
CCHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCHHCCCCCCCCCCCCEEECCCEEE
QNNVSIYEGTVIEDDVFLGPSCVLTNVTNPRSQVVRRSLYETTLLRRGCSIGANATIVCG
ECCCEEEECEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ITIGRYAFVAAGAVVAKDVPDYALMVGVPARQKGWMSRHGLPLTPGPDGIMVCKESGYCY
EEHHHHHHHHHCHHHCCCCCCEEEEEECCCHHCCCHHHCCCCCCCCCCCEEEECCCCCCH
QEVQPGLLKCLDLDEDAPLPSEKAVGSVCYDDLK
HHCCCCHHEEECCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SEFFAHQSSYIDEGAEIGAGTKIWHFSHIMSGATIGERCSFGQNCVVSPGVVIGSNVKV
CHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCCHHCCCCCCCCCCCCEEECCCEEE
QNNVSIYEGTVIEDDVFLGPSCVLTNVTNPRSQVVRRSLYETTLLRRGCSIGANATIVCG
ECCCEEEECEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ITIGRYAFVAAGAVVAKDVPDYALMVGVPARQKGWMSRHGLPLTPGPDGIMVCKESGYCY
EEHHHHHHHHHCHHHCCCCCCEEEEEECCCHHCCCHHHCCCCCCCCCCCEEEECCCCCCH
QEVQPGLLKCLDLDEDAPLPSEKAVGSVCYDDLK
HHCCCCHHEEECCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA