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The map label for this gene is hsdR [H]

Identifier: 189424480

GI number: 189424480

Start: 1461750

End: 1464152

Strand: Reverse

Name: hsdR [H]

Synonym: Glov_1416

Alternate gene names: 189424480

Gene position: 1464152-1461750 (Counterclockwise)

Preceding gene: 189424481

Following gene: 189424479

Centisome position: 37.37

GC content: 54.02

Gene sequence:

>2403_bases
ATGACCTCTAAGAAAAATCTTTCAGAACGCGATATCTGCACCCAGTACATTGTGCCTGCCCTGAAAAAGGCCGGGTGGGA
TATCGAGCGTCAGGTACGAGAGGAGGTTTCTTTCACCGATGGTCGCATCTACGTGCGCGGCACTAGCTCTGCTCGTGGTA
GCCGCAAGCGGGCTGACTTTATCCTCTACTACAAGCCGAATATCCCCATTGCCGTCATAGAGGCCAAGGACAACAGCCAT
AACGTGGGCGACGGCATGCAGCAGGCTCTTGGCTATGCTGCAACCCTTGATATCCCGGTAGCATTCAGTTCCAACGGTGA
CGGGTTCGTGGAACATGACCGCACTGGTTCATCCGGCAGTGTAGAGCGCACGCTCCACCTTGATGATTTCCCCTCTCCTG
AAGAACTCTGGCAACGCTACAAAACATACAAAGGGATTGATACCCCGCATCAGGAACAGATTGCCTCTTTTGACTACTTC
TATGATGGTTCCGGCCGGGCGCCCCGCTACTACCAGCAGATAGCCATTAACCGCTCCGTCGAAGCAATTGCTAAAGGGCA
AGACCGGATTCTACTGGTCATGGCCACCGGCACCGGCAAGACCTACACCGCCTTTCAGATCATCCACCGTCTCTGGAAGA
GTGGCACCAAGAAACGCATCCTGTTCCTGGCCGACCGTAATGCCTTGATCGACCAGACCAAACGGGGCGACTTCAAGCAT
TTCAAGGACCGAATGACGGTCATCCGCAAGAAGAAGATCGACAAGGCCTTTGAGATTTATCTTGCCCTTTATCAGGGGTT
GACCAATTACGACGAGGATTCAGACGCCTACCGGGAGTTCAGCCCGGATTTCTTTGACCTGATCGTGGTGGATGAATGCC
ACCGTGGCAGCGCATCCGCTGACAGCGCCTGGCGGGAGATTCTGGACTACTTCAAAAGCGCCACTCATATCGGTCTCACC
GCCACACCGAAGGAAACCAAGACCGTCTCCAATATTGAATACTTCGGCGAACCGCTCTACACCTACTCCCTCCGGCAAGG
GATTGCCGATGGTTTTCTCGCTCCTTACAAAGTGCTCCGTGTCGGCCTTAACATCGACCTGGAAGGGTGGCGGCCGGAAG
AAGGTCAACTGGATGCCGACGGCAATCCGGTGGACGACCGGCTCTACAACACCAAGGATTTCGACCGTAACCTAGTCATT
GATGAACGTACCAGGACTATTGCCCGCAAGGTGACGGAGTTTCTCAAAAAGACCGACCCCTTCGACAAAACCATTGTTTT
CTGTGTCGATATCGAACACGCCACTCGTATGCGCCAAGCTCTGGCCAACGCCAATCCTGAAGAGGTACTGAAGAATCATA
AGTATGTCATGAAGATCACCGGCGATGACGATGACGGCAAGCGGGAGCTGGATAATTTCATCAACCCCGAAGAGCGCTAC
CCGGTCATTGCTGTGACCTCCAAACTGATGACCACCGGCGTCGATGCCCAGACCTGCAAATTGATTGTGCTTGATTCCAA
TATCAATTCCCCGACTGAGTTCAAGCAGATCATTGGACGTGGTACGCGCATCAACGAGGAGTTCGGCAAGCGCTACTTCA
CCATCATGGATTTCCGCAACGTGACCGACCTGTTTGCCGATCCGGATTTTGACGGCGACCCGGTCATGGTGAAGCAACTG
CTGGCAGATGATGAACTGACCGAAGCCGATATCCATCCCGAAGACGAGCCGGTCGTGGATGAAGAAACCGGGGACGAAAT
CCCCTTTGGTGATGACAAACCGGAAGTGACCTATGACCGCCCGGAGATCATCGATGGCGGCGGCATTGTGGCCGAGCCCC
TACCAAAGATCTATGTGGCTGGTGTCGATGTCTCGATCCTCAATGAGCGGGTGCAGTATCTGGGGGCCAACGGCAAGCTC
ACCACCGGCAGCCTGAAGGAGTTCACCCGCACCGGCCTACTGAATGAGTTCCGCACGCTCGATGACTTCCTGTCCCGCTG
GAACAGTGCCGAAAAGAAGAAAGCGGTGATCGACCAGCTGGCTGAGCATGACATTATTCTGGAAAATCTGCTGGATGAGA
CAAAGAAGGAGCTGGACCTGTTCGACCTGATCTGCCACATCGCCTGGGATCGGCCAGCACTTACCAGAAGAGAAAGAGCC
GAGCAGGTAACAAAACGTGATTACTTCACGCGGTATGGTGACAATGCCCGTCAAGTCTTGCAGGCGCTACTGGAAAAATA
CGCCAAAGACGGTATCGAGAACATCGAAGAGATGAAGGTGCTGACCATTGACCCGTTCAAGGCAATCGGCACCCCGGCTG
AGATCGTCCATCTCTTCGGCGGCAAGGAAGCCTATCAGGCGGCAGTGAGAGAGCTGGAAACTGAAATTTACAGGATGGCG
TAA

Upstream 100 bases:

>100_bases
TATTTGAAATAGCCGGGTCTCTAGCGCAAATGACATATTCTGTCGCATAGCTGTGGTATATGGAATGATACCCAATCAGA
CATGAACATCGTGAGTGATC

Downstream 100 bases:

>100_bases
TTCATGAAAAATATCGGCACCATCATCAAACGGCTGCAGAACACCATGCGCAAGGATCAAGGCGTCTCCGGTGATGCCCA
ACGCATCGAACAGCTTGGCT

Product: EcoEI R domain-containing protein

Products: NA

Alternate protein names: R.EcoAI [H]

Number of amino acids: Translated: 800; Mature: 799

Protein sequence:

>800_residues
MTSKKNLSERDICTQYIVPALKKAGWDIERQVREEVSFTDGRIYVRGTSSARGSRKRADFILYYKPNIPIAVIEAKDNSH
NVGDGMQQALGYAATLDIPVAFSSNGDGFVEHDRTGSSGSVERTLHLDDFPSPEELWQRYKTYKGIDTPHQEQIASFDYF
YDGSGRAPRYYQQIAINRSVEAIAKGQDRILLVMATGTGKTYTAFQIIHRLWKSGTKKRILFLADRNALIDQTKRGDFKH
FKDRMTVIRKKKIDKAFEIYLALYQGLTNYDEDSDAYREFSPDFFDLIVVDECHRGSASADSAWREILDYFKSATHIGLT
ATPKETKTVSNIEYFGEPLYTYSLRQGIADGFLAPYKVLRVGLNIDLEGWRPEEGQLDADGNPVDDRLYNTKDFDRNLVI
DERTRTIARKVTEFLKKTDPFDKTIVFCVDIEHATRMRQALANANPEEVLKNHKYVMKITGDDDDGKRELDNFINPEERY
PVIAVTSKLMTTGVDAQTCKLIVLDSNINSPTEFKQIIGRGTRINEEFGKRYFTIMDFRNVTDLFADPDFDGDPVMVKQL
LADDELTEADIHPEDEPVVDEETGDEIPFGDDKPEVTYDRPEIIDGGGIVAEPLPKIYVAGVDVSILNERVQYLGANGKL
TTGSLKEFTRTGLLNEFRTLDDFLSRWNSAEKKKAVIDQLAEHDIILENLLDETKKELDLFDLICHIAWDRPALTRRERA
EQVTKRDYFTRYGDNARQVLQALLEKYAKDGIENIEEMKVLTIDPFKAIGTPAEIVHLFGGKEAYQAAVRELETEIYRMA

Sequences:

>Translated_800_residues
MTSKKNLSERDICTQYIVPALKKAGWDIERQVREEVSFTDGRIYVRGTSSARGSRKRADFILYYKPNIPIAVIEAKDNSH
NVGDGMQQALGYAATLDIPVAFSSNGDGFVEHDRTGSSGSVERTLHLDDFPSPEELWQRYKTYKGIDTPHQEQIASFDYF
YDGSGRAPRYYQQIAINRSVEAIAKGQDRILLVMATGTGKTYTAFQIIHRLWKSGTKKRILFLADRNALIDQTKRGDFKH
FKDRMTVIRKKKIDKAFEIYLALYQGLTNYDEDSDAYREFSPDFFDLIVVDECHRGSASADSAWREILDYFKSATHIGLT
ATPKETKTVSNIEYFGEPLYTYSLRQGIADGFLAPYKVLRVGLNIDLEGWRPEEGQLDADGNPVDDRLYNTKDFDRNLVI
DERTRTIARKVTEFLKKTDPFDKTIVFCVDIEHATRMRQALANANPEEVLKNHKYVMKITGDDDDGKRELDNFINPEERY
PVIAVTSKLMTTGVDAQTCKLIVLDSNINSPTEFKQIIGRGTRINEEFGKRYFTIMDFRNVTDLFADPDFDGDPVMVKQL
LADDELTEADIHPEDEPVVDEETGDEIPFGDDKPEVTYDRPEIIDGGGIVAEPLPKIYVAGVDVSILNERVQYLGANGKL
TTGSLKEFTRTGLLNEFRTLDDFLSRWNSAEKKKAVIDQLAEHDIILENLLDETKKELDLFDLICHIAWDRPALTRRERA
EQVTKRDYFTRYGDNARQVLQALLEKYAKDGIENIEEMKVLTIDPFKAIGTPAEIVHLFGGKEAYQAAVRELETEIYRMA
>Mature_799_residues
TSKKNLSERDICTQYIVPALKKAGWDIERQVREEVSFTDGRIYVRGTSSARGSRKRADFILYYKPNIPIAVIEAKDNSHN
VGDGMQQALGYAATLDIPVAFSSNGDGFVEHDRTGSSGSVERTLHLDDFPSPEELWQRYKTYKGIDTPHQEQIASFDYFY
DGSGRAPRYYQQIAINRSVEAIAKGQDRILLVMATGTGKTYTAFQIIHRLWKSGTKKRILFLADRNALIDQTKRGDFKHF
KDRMTVIRKKKIDKAFEIYLALYQGLTNYDEDSDAYREFSPDFFDLIVVDECHRGSASADSAWREILDYFKSATHIGLTA
TPKETKTVSNIEYFGEPLYTYSLRQGIADGFLAPYKVLRVGLNIDLEGWRPEEGQLDADGNPVDDRLYNTKDFDRNLVID
ERTRTIARKVTEFLKKTDPFDKTIVFCVDIEHATRMRQALANANPEEVLKNHKYVMKITGDDDDGKRELDNFINPEERYP
VIAVTSKLMTTGVDAQTCKLIVLDSNINSPTEFKQIIGRGTRINEEFGKRYFTIMDFRNVTDLFADPDFDGDPVMVKQLL
ADDELTEADIHPEDEPVVDEETGDEIPFGDDKPEVTYDRPEIIDGGGIVAEPLPKIYVAGVDVSILNERVQYLGANGKLT
TGSLKEFTRTGLLNEFRTLDDFLSRWNSAEKKKAVIDQLAEHDIILENLLDETKKELDLFDLICHIAWDRPALTRRERAE
QVTKRDYFTRYGDNARQVLQALLEKYAKDGIENIEEMKVLTIDPFKAIGTPAEIVHLFGGKEAYQAAVRELETEIYRMA

Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI226510991, Length=656, Percent_Identity=29.7256097560976, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6320539, Length=395, Percent_Identity=26.3291139240506, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 91207; Mature: 91075

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKKNLSERDICTQYIVPALKKAGWDIERQVREEVSFTDGRIYVRGTSSARGSRKRADF
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCE
ILYYKPNIPIAVIEAKDNSHNVGDGMQQALGYAATLDIPVAFSSNGDGFVEHDRTGSSGS
EEEECCCCCEEEEEECCCCCCCCHHHHHHHCEEEEEEEEEEECCCCCCCEECCCCCCCCC
VERTLHLDDFPSPEELWQRYKTYKGIDTPHQEQIASFDYFYDGSGRAPRYYQQIAINRSV
CEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCH
EAIAKGQDRILLVMATGTGKTYTAFQIIHRLWKSGTKKRILFLADRNALIDQTKRGDFKH
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCCCCHHH
FKDRMTVIRKKKIDKAFEIYLALYQGLTNYDEDSDAYREFSPDFFDLIVVDECHRGSASA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCH
DSAWREILDYFKSATHIGLTATPKETKTVSNIEYFGEPLYTYSLRQGIADGFLAPYKVLR
HHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
VGLNIDLEGWRPEEGQLDADGNPVDDRLYNTKDFDRNLVIDERTRTIARKVTEFLKKTDP
CCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCC
FDKTIVFCVDIEHATRMRQALANANPEEVLKNHKYVMKITGDDDDGKRELDNFINPEERY
CCCEEEEEEECHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCHHCC
PVIAVTSKLMTTGVDAQTCKLIVLDSNINSPTEFKQIIGRGTRINEEFGKRYFTIMDFRN
CEEEEEHHHHHCCCCHHHEEEEEEECCCCCHHHHHHHHCCCCCCCHHHCCCEEEEEEHHH
VTDLFADPDFDGDPVMVKQLLADDELTEADIHPEDEPVVDEETGDEIPFGDDKPEVTYDR
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC
PEIIDGGGIVAEPLPKIYVAGVDVSILNERVQYLGANGKLTTGSLKEFTRTGLLNEFRTL
CCEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DDFLSRWNSAEKKKAVIDQLAEHDIILENLLDETKKELDLFDLICHIAWDRPALTRRERA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQVTKRDYFTRYGDNARQVLQALLEKYAKDGIENIEEMKVLTIDPFKAIGTPAEIVHLFG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHCCHHHHHHHHC
GKEAYQAAVRELETEIYRMA
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSKKNLSERDICTQYIVPALKKAGWDIERQVREEVSFTDGRIYVRGTSSARGSRKRADF
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCE
ILYYKPNIPIAVIEAKDNSHNVGDGMQQALGYAATLDIPVAFSSNGDGFVEHDRTGSSGS
EEEECCCCCEEEEEECCCCCCCCHHHHHHHCEEEEEEEEEEECCCCCCCEECCCCCCCCC
VERTLHLDDFPSPEELWQRYKTYKGIDTPHQEQIASFDYFYDGSGRAPRYYQQIAINRSV
CEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCH
EAIAKGQDRILLVMATGTGKTYTAFQIIHRLWKSGTKKRILFLADRNALIDQTKRGDFKH
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCCCCHHH
FKDRMTVIRKKKIDKAFEIYLALYQGLTNYDEDSDAYREFSPDFFDLIVVDECHRGSASA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCH
DSAWREILDYFKSATHIGLTATPKETKTVSNIEYFGEPLYTYSLRQGIADGFLAPYKVLR
HHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHH
VGLNIDLEGWRPEEGQLDADGNPVDDRLYNTKDFDRNLVIDERTRTIARKVTEFLKKTDP
CCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCC
FDKTIVFCVDIEHATRMRQALANANPEEVLKNHKYVMKITGDDDDGKRELDNFINPEERY
CCCEEEEEEECHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCHHCC
PVIAVTSKLMTTGVDAQTCKLIVLDSNINSPTEFKQIIGRGTRINEEFGKRYFTIMDFRN
CEEEEEHHHHHCCCCHHHEEEEEEECCCCCHHHHHHHHCCCCCCCHHHCCCEEEEEEHHH
VTDLFADPDFDGDPVMVKQLLADDELTEADIHPEDEPVVDEETGDEIPFGDDKPEVTYDR
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC
PEIIDGGGIVAEPLPKIYVAGVDVSILNERVQYLGANGKLTTGSLKEFTRTGLLNEFRTL
CCEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DDFLSRWNSAEKKKAVIDQLAEHDIILENLLDETKKELDLFDLICHIAWDRPALTRRERA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQVTKRDYFTRYGDNARQVLQALLEKYAKDGIENIEEMKVLTIDPFKAIGTPAEIVHLFG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHCCHHHHHHHHC
GKEAYQAAVRELETEIYRMA
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]