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The map label for this gene is rnr [H]

Identifier: 189424308

GI number: 189424308

Start: 1291313

End: 1293571

Strand: Reverse

Name: rnr [H]

Synonym: Glov_1243

Alternate gene names: 189424308

Gene position: 1293571-1291313 (Counterclockwise)

Preceding gene: 189424309

Following gene: 189424307

Centisome position: 33.02

GC content: 59.5

Gene sequence:

>2259_bases
ATGCTCCTGCACAAAAAAGAGATACTGAACCTGCTGGCTGAAGAACCCGAGGCACTGCACTTTGCCTCACTGCTCCGCGC
CTTTGGCGGCCGCCATATCAAAAACGAGCTCAAGCAGATTGTGGATGACCTGGTACGCAGTGGCGAGATCCTGCGTCTGC
GGGGCAACCGTTATACCCTGCCGGGAGCCGACAACAGCGGCACCGTGCAGGGCAGCATCTCGATTCACCGCGATGGGTAC
GGCTTTGTCAAGCCTGAGAGCGGCGGCGAGGACATCTTTATCCCGGGCAAGAACATCAATAACGCCCTGCATGGTGACAA
GGTATCGGTCAGGGCCGAGAAGAGCCGCTCCCAGCGCGGCAAGCTGGAAGGCCGGGTGGTTGCCGTACTGGAACGGGCCA
ACAGCCGGATTGTGGGGCGCCTGCAGCAAAGCAGGCGTGGCGCAACCGTGGTTCCGGAAGAGTTGCGGATCGGCACCTTC
TTCACCGTACCGGCCAATGCAGTCAATGGCGCGGTTGATGGGCAGCAGGTGGTGATTGAAGTGACCGCCTGGCCGGTCGG
GGGGCGTCCGCCCGAAGGCAAAGTGGTTGAAATCCTGGGCTGGCCCGACGACCCTGATGTTGAAGTACAGACGGTGATCC
GCAAGTTTGATCTGCCCCACACCTTTGAACCGGAGACGCTGGCAGAGGCCCAGGCAATCCCCTCTCAGGTCGGCAAAAAC
GATCTGAAGGACCGGGTTGACCTGCGCAAGCTGCCCACCGTGACCATTGACGGAGAAACGGCCAAAGACTTTGACGATGC
CGTTTCCATCCGGCAGGAAGGTCATAATTTCCGGCTCTGGGTATCCATTGCCGATGTTTCACACTACATTGAACCGGGGA
GCATGCTTGATCGCGAGGCCTACCTGCGCGGCACGTCGGTCTACTTTCCGGACCGTTGCATCCCGATGCTGCCGGAACGC
CTCTCAAACGGCATCTGCTCCCTGAATCCCCACCTGGACCGGCTGACCATGACCGCCGAGATGCTCTTTGACCAACAGGG
CAGGATGCTTGAATCCAGCTTCTATTCCAGCGTGATCAAGAGCGATGCCCGCCTGACCTATACCAAGGTCAAGCAGGTCA
TCATCGACGGCGATGAAAAGGTACTTGAAGAGGATCGCGGCCTGGCTCCGATGCTGTTGCAGATGAAAGAGCTGGCCCTG
ATTCTGCAGACGATGCGCAGGCAACGGGGCAGCATCGACTTTGACCTGCCGGAACCGGAGATCATCCTCGGCCTGACCGG
CCAGACCGAGGCGATCATCAAGAGTGAGCGCAATCTGGCCCACCAACTGATTGAAGAGTTCATGCTGGCTGCCAACGAGG
CCGTAGCACGCTTTGTGTCCGGGCAGGAGATGGCATTCATCTACCGGGTCCATGAGCCGCCTGACCCAACCAAGCTGACC
GCCTTCCGTGACTTTATCCTTCCCTTTGGCTTCACTCTGGAGATGCAGGGGGATCGGGTTGAGCCATCAGCCATGCAACG
CTTGATCAGCGATGCAGAGGGTAAGCCGGAAGAGCGGCTGGTTAACTACGGCCTGCTGCGTTGCATGAAGCAGGCCCGCT
ATGCTGCTGAAAATCTGAAGCACTTTGGCCTGGCCTCCAGCTGCTACACCCACTTTACCTCGCCGATCCGGCGCTATCCC
GACCTGATTGTCCACCGTCTGCTCCGGTTGGCACTGGAGCGCAAAGCCGGGACACTGGGCAAAAAAGGACAGCGCGAACT
GGACCGGATAGGCAGTACCCTTTCCGAAGCGGCCGAGCATACCAGCACCCGTGAACGGGTAGCCATGGAGGCAGAACGGG
ATATTGTCGAGCTGAAAAAACTGCAGTTCATGCAGGGCAGGATCGGCCAGGAGTTTGACGGCTTTATCGCCGGGGTGGCC
GGTTTCGGCTGTTTCGTAGAACTGTCCGAGGTCTTTGTGGAAGGACTGGTACATATTTCCACCCTGGCGGACGACCTCTA
CAACTTTGATGAACAAAACCACGCACTGATCGGCCGGCGTTCCGGACGCACCTTGCGGATCGGCGACCCTGTCCGGGTAC
GGGTGGTGGCGGTCAATCCTCAGGCCCGCAGAATCGAGTTTGTACTGGAAAGCCACAGCACAGTCCGCAGGGACGTGGCT
GCGGCACAACCGGCTGCCCCAGAGGAGTATCCACGCATTCCGATCAGGGGAAAGCGTCCGGTGCCGAAGGGCGCCGGCAA
CGGAAATCGCCGGCGTTAG

Upstream 100 bases:

>100_bases
CCGCTCGTCGCCTCCAATATAAAAGGGGTTAGCTCATACAGCTAACCCCTTTTCCTGTTCAATCAACCATAGATTCACCC
TAAAGGAAATGGTTTCTGCG

Downstream 100 bases:

>100_bases
TTGCGCCTTTGCAACGCCTGTGCTAGTTTTGCCCGATTACCACCTACAGGAGCAGTCATGTCTGAAGAGCCATCCAAAGT
TCTCCCCTTTATCGAGCATC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MLLHKKEILNLLAEEPEALHFASLLRAFGGRHIKNELKQIVDDLVRSGEILRLRGNRYTLPGADNSGTVQGSISIHRDGY
GFVKPESGGEDIFIPGKNINNALHGDKVSVRAEKSRSQRGKLEGRVVAVLERANSRIVGRLQQSRRGATVVPEELRIGTF
FTVPANAVNGAVDGQQVVIEVTAWPVGGRPPEGKVVEILGWPDDPDVEVQTVIRKFDLPHTFEPETLAEAQAIPSQVGKN
DLKDRVDLRKLPTVTIDGETAKDFDDAVSIRQEGHNFRLWVSIADVSHYIEPGSMLDREAYLRGTSVYFPDRCIPMLPER
LSNGICSLNPHLDRLTMTAEMLFDQQGRMLESSFYSSVIKSDARLTYTKVKQVIIDGDEKVLEEDRGLAPMLLQMKELAL
ILQTMRRQRGSIDFDLPEPEIILGLTGQTEAIIKSERNLAHQLIEEFMLAANEAVARFVSGQEMAFIYRVHEPPDPTKLT
AFRDFILPFGFTLEMQGDRVEPSAMQRLISDAEGKPEERLVNYGLLRCMKQARYAAENLKHFGLASSCYTHFTSPIRRYP
DLIVHRLLRLALERKAGTLGKKGQRELDRIGSTLSEAAEHTSTRERVAMEAERDIVELKKLQFMQGRIGQEFDGFIAGVA
GFGCFVELSEVFVEGLVHISTLADDLYNFDEQNHALIGRRSGRTLRIGDPVRVRVVAVNPQARRIEFVLESHSTVRRDVA
AAQPAAPEEYPRIPIRGKRPVPKGAGNGNRRR

Sequences:

>Translated_752_residues
MLLHKKEILNLLAEEPEALHFASLLRAFGGRHIKNELKQIVDDLVRSGEILRLRGNRYTLPGADNSGTVQGSISIHRDGY
GFVKPESGGEDIFIPGKNINNALHGDKVSVRAEKSRSQRGKLEGRVVAVLERANSRIVGRLQQSRRGATVVPEELRIGTF
FTVPANAVNGAVDGQQVVIEVTAWPVGGRPPEGKVVEILGWPDDPDVEVQTVIRKFDLPHTFEPETLAEAQAIPSQVGKN
DLKDRVDLRKLPTVTIDGETAKDFDDAVSIRQEGHNFRLWVSIADVSHYIEPGSMLDREAYLRGTSVYFPDRCIPMLPER
LSNGICSLNPHLDRLTMTAEMLFDQQGRMLESSFYSSVIKSDARLTYTKVKQVIIDGDEKVLEEDRGLAPMLLQMKELAL
ILQTMRRQRGSIDFDLPEPEIILGLTGQTEAIIKSERNLAHQLIEEFMLAANEAVARFVSGQEMAFIYRVHEPPDPTKLT
AFRDFILPFGFTLEMQGDRVEPSAMQRLISDAEGKPEERLVNYGLLRCMKQARYAAENLKHFGLASSCYTHFTSPIRRYP
DLIVHRLLRLALERKAGTLGKKGQRELDRIGSTLSEAAEHTSTRERVAMEAERDIVELKKLQFMQGRIGQEFDGFIAGVA
GFGCFVELSEVFVEGLVHISTLADDLYNFDEQNHALIGRRSGRTLRIGDPVRVRVVAVNPQARRIEFVLESHSTVRRDVA
AAQPAAPEEYPRIPIRGKRPVPKGAGNGNRRR
>Mature_752_residues
MLLHKKEILNLLAEEPEALHFASLLRAFGGRHIKNELKQIVDDLVRSGEILRLRGNRYTLPGADNSGTVQGSISIHRDGY
GFVKPESGGEDIFIPGKNINNALHGDKVSVRAEKSRSQRGKLEGRVVAVLERANSRIVGRLQQSRRGATVVPEELRIGTF
FTVPANAVNGAVDGQQVVIEVTAWPVGGRPPEGKVVEILGWPDDPDVEVQTVIRKFDLPHTFEPETLAEAQAIPSQVGKN
DLKDRVDLRKLPTVTIDGETAKDFDDAVSIRQEGHNFRLWVSIADVSHYIEPGSMLDREAYLRGTSVYFPDRCIPMLPER
LSNGICSLNPHLDRLTMTAEMLFDQQGRMLESSFYSSVIKSDARLTYTKVKQVIIDGDEKVLEEDRGLAPMLLQMKELAL
ILQTMRRQRGSIDFDLPEPEIILGLTGQTEAIIKSERNLAHQLIEEFMLAANEAVARFVSGQEMAFIYRVHEPPDPTKLT
AFRDFILPFGFTLEMQGDRVEPSAMQRLISDAEGKPEERLVNYGLLRCMKQARYAAENLKHFGLASSCYTHFTSPIRRYP
DLIVHRLLRLALERKAGTLGKKGQRELDRIGSTLSEAAEHTSTRERVAMEAERDIVELKKLQFMQGRIGQEFDGFIAGVA
GFGCFVELSEVFVEGLVHISTLADDLYNFDEQNHALIGRRSGRTLRIGDPVRVRVVAVNPQARRIEFVLESHSTVRRDVA
AAQPAAPEEYPRIPIRGKRPVPKGAGNGNRRR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=557, Percent_Identity=30.3411131059246, Blast_Score=213, Evalue=8e-55,
Organism=Homo sapiens, GI190014625, Length=557, Percent_Identity=30.3411131059246, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI134288890, Length=561, Percent_Identity=28.5204991087344, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI19115966, Length=612, Percent_Identity=26.3071895424837, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI219521928, Length=612, Percent_Identity=26.3071895424837, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI156105693, Length=490, Percent_Identity=25.3061224489796, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI156105695, Length=490, Percent_Identity=25.3061224489796, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI87082383, Length=696, Percent_Identity=39.2241379310345, Blast_Score=477, Evalue=1e-135,
Organism=Escherichia coli, GI1787542, Length=578, Percent_Identity=27.1626297577855, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI212645896, Length=712, Percent_Identity=26.8258426966292, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17553506, Length=500, Percent_Identity=28.8, Blast_Score=162, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=623, Percent_Identity=27.1268057784912, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320499, Length=572, Percent_Identity=22.2027972027972, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24649634, Length=728, Percent_Identity=28.4340659340659, Blast_Score=219, Evalue=7e-57,
Organism=Drosophila melanogaster, GI19922976, Length=364, Percent_Identity=34.0659340659341, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24654597, Length=364, Percent_Identity=34.0659340659341, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24654592, Length=364, Percent_Identity=34.0659340659341, Blast_Score=180, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84190; Mature: 84190

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLHKKEILNLLAEEPEALHFASLLRAFGGRHIKNELKQIVDDLVRSGEILRLRGNRYTL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEC
PGADNSGTVQGSISIHRDGYGFVKPESGGEDIFIPGKNINNALHGDKVSVRAEKSRSQRG
CCCCCCCEEEEEEEEEECCCCEECCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHHHHCC
KLEGRVVAVLERANSRIVGRLQQSRRGATVVPEELRIGTFFTVPANAVNGAVDGQQVVIE
CCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHCEECEEEECCCHHHCCCCCCCEEEEE
VTAWPVGGRPPEGKVVEILGWPDDPDVEVQTVIRKFDLPHTFEPETLAEAQAIPSQVGKN
EEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHH
DLKDRVDLRKLPTVTIDGETAKDFDDAVSIRQEGHNFRLWVSIADVSHYIEPGSMLDREA
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECHHHHCCCCHHHCHHH
YLRGTSVYFPDRCIPMLPERLSNGICSLNPHLDRLTMTAEMLFDQQGRMLESSFYSSVIK
HHCCCCEECCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SDARLTYTKVKQVIIDGDEKVLEEDRGLAPMLLQMKELALILQTMRRQRGSIDFDLPEPE
CCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IILGLTGQTEAIIKSERNLAHQLIEEFMLAANEAVARFVSGQEMAFIYRVHEPPDPTKLT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
AFRDFILPFGFTLEMQGDRVEPSAMQRLISDAEGKPEERLVNYGLLRCMKQARYAAENLK
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFGLASSCYTHFTSPIRRYPDLIVHRLLRLALERKAGTLGKKGQRELDRIGSTLSEAAEH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TSTRERVAMEAERDIVELKKLQFMQGRIGQEFDGFIAGVAGFGCFVELSEVFVEGLVHIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADDLYNFDEQNHALIGRRSGRTLRIGDPVRVRVVAVNPQARRIEFVLESHSTVRRDVA
HHHHHHHCCCCCCCEEEEECCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
AAQPAAPEEYPRIPIRGKRPVPKGAGNGNRRR
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLHKKEILNLLAEEPEALHFASLLRAFGGRHIKNELKQIVDDLVRSGEILRLRGNRYTL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEC
PGADNSGTVQGSISIHRDGYGFVKPESGGEDIFIPGKNINNALHGDKVSVRAEKSRSQRG
CCCCCCCEEEEEEEEEECCCCEECCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHHHHCC
KLEGRVVAVLERANSRIVGRLQQSRRGATVVPEELRIGTFFTVPANAVNGAVDGQQVVIE
CCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHCEECEEEECCCHHHCCCCCCCEEEEE
VTAWPVGGRPPEGKVVEILGWPDDPDVEVQTVIRKFDLPHTFEPETLAEAQAIPSQVGKN
EEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHH
DLKDRVDLRKLPTVTIDGETAKDFDDAVSIRQEGHNFRLWVSIADVSHYIEPGSMLDREA
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECHHHHCCCCHHHCHHH
YLRGTSVYFPDRCIPMLPERLSNGICSLNPHLDRLTMTAEMLFDQQGRMLESSFYSSVIK
HHCCCCEECCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SDARLTYTKVKQVIIDGDEKVLEEDRGLAPMLLQMKELALILQTMRRQRGSIDFDLPEPE
CCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IILGLTGQTEAIIKSERNLAHQLIEEFMLAANEAVARFVSGQEMAFIYRVHEPPDPTKLT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
AFRDFILPFGFTLEMQGDRVEPSAMQRLISDAEGKPEERLVNYGLLRCMKQARYAAENLK
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFGLASSCYTHFTSPIRRYPDLIVHRLLRLALERKAGTLGKKGQRELDRIGSTLSEAAEH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TSTRERVAMEAERDIVELKKLQFMQGRIGQEFDGFIAGVAGFGCFVELSEVFVEGLVHIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADDLYNFDEQNHALIGRRSGRTLRIGDPVRVRVVAVNPQARRIEFVLESHSTVRRDVA
HHHHHHHCCCCCCCEEEEECCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
AAQPAAPEEYPRIPIRGKRPVPKGAGNGNRRR
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]