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The map label for this gene is pkn1 [H]

Identifier: 189424234

GI number: 189424234

Start: 1223185

End: 1224024

Strand: Reverse

Name: pkn1 [H]

Synonym: Glov_1169

Alternate gene names: 189424234

Gene position: 1224024-1223185 (Counterclockwise)

Preceding gene: 189424235

Following gene: 189424233

Centisome position: 31.24

GC content: 52.38

Gene sequence:

>840_bases
ATGGGTACTCCCTCGATTAAAAAGCATCTATACACCCTTTCAGCCCTCACCTGGTTGACCATACTGCTGTTGCCAGTGAT
CTGTGATGCTCATGATGCACTGTTGGTGCCTGATGAGCTGAGACAACGCAGCGACATCGAACTTGTCCCGGTAAAAGGGG
GCTGCTTTCAGATGGGTGAATTCATTCTTGAAAGCGCTGGCGACGAGAAGCCGGTTCATGAGGTCTGTGTATCAGACTTT
ATGATTGCCAAATACGAGGTCACGCAGGGGCAATGGAAACAGTTCATGGGCAATAGGCCATCCAACTTCAGGGATTGCGG
CGACAGCTGCCCGGTTGAGCAGGTCAGCTGGAATGAGGTTCAACAGTTTATCCAACGCCTGAACAGACAAACCGGACTAC
AGTTCCGTCTCCCCAGCGAGGCTGAATGGGAATACGCCTGTCGCAGCGGTGGTAAACAGGAGAAGTTCTGTGGAGGTAAC
GACATTGATGTTCTGGCCTGGCACCATGACAATTCCGATGGCAGACCACATCCAGTTGGACAGAAAAAGCCTAATGGACT
CGGCATCTATGATATGAGCGGCAATGTGTGGGAATGGGTGCAGGACTGGTTTGATACGAGCTATTATAGCAAAAGCCCGA
GGATGAATCCTCAAGGCCCCACTACATCCTCTGAAAAGGCCGTCCGGGGTGGCTGCTGGGATTGCGAACCCAAATGCATC
CGCGCATCCATTCGCTACTGGTTTGCTCCCAACGGGCGTTTCAGTGGCCTTGGGTTCCGGCTTGCCCACCCGACAGCTGT
CAGCGTCAAACATTCAGGAGGTAAAACAGATGAGCAATGA

Upstream 100 bases:

>100_bases
GGCACGGCGCACAGATACTACCACTGGTGATTACTCAAACAAAAGACAGCGGCTAAACAGGACAGTCTTCTTCCTTTGCT
GTCCCAGGAGACAGACCTGC

Downstream 100 bases:

>100_bases
TGAGCGCTCAGTTGAAACAATAGAACTCAATATCCTCGGCCAGGTCTGCCCAGCCTGCCTGTTGGTAGTACTCAAGCAGA
TCAACCAATATCGGGAACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MGTPSIKKHLYTLSALTWLTILLLPVICDAHDALLVPDELRQRSDIELVPVKGGCFQMGEFILESAGDEKPVHEVCVSDF
MIAKYEVTQGQWKQFMGNRPSNFRDCGDSCPVEQVSWNEVQQFIQRLNRQTGLQFRLPSEAEWEYACRSGGKQEKFCGGN
DIDVLAWHHDNSDGRPHPVGQKKPNGLGIYDMSGNVWEWVQDWFDTSYYSKSPRMNPQGPTTSSEKAVRGGCWDCEPKCI
RASIRYWFAPNGRFSGLGFRLAHPTAVSVKHSGGKTDEQ

Sequences:

>Translated_279_residues
MGTPSIKKHLYTLSALTWLTILLLPVICDAHDALLVPDELRQRSDIELVPVKGGCFQMGEFILESAGDEKPVHEVCVSDF
MIAKYEVTQGQWKQFMGNRPSNFRDCGDSCPVEQVSWNEVQQFIQRLNRQTGLQFRLPSEAEWEYACRSGGKQEKFCGGN
DIDVLAWHHDNSDGRPHPVGQKKPNGLGIYDMSGNVWEWVQDWFDTSYYSKSPRMNPQGPTTSSEKAVRGGCWDCEPKCI
RASIRYWFAPNGRFSGLGFRLAHPTAVSVKHSGGKTDEQ
>Mature_278_residues
GTPSIKKHLYTLSALTWLTILLLPVICDAHDALLVPDELRQRSDIELVPVKGGCFQMGEFILESAGDEKPVHEVCVSDFM
IAKYEVTQGQWKQFMGNRPSNFRDCGDSCPVEQVSWNEVQQFIQRLNRQTGLQFRLPSEAEWEYACRSGGKQEKFCGGND
IDVLAWHHDNSDGRPHPVGQKKPNGLGIYDMSGNVWEWVQDWFDTSYYSKSPRMNPQGPTTSSEKAVRGGCWDCEPKCIR
ASIRYWFAPNGRFSGLGFRLAHPTAVSVKHSGGKTDEQ

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=270, Percent_Identity=30, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38202250, Length=169, Percent_Identity=33.7278106508876, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI257470977, Length=292, Percent_Identity=26.7123287671233, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130397, Length=282, Percent_Identity=27.3049645390071, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31491; Mature: 31360

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTPSIKKHLYTLSALTWLTILLLPVICDAHDALLVPDELRQRSDIELVPVKGGCFQMGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCCCEEEECCCCHHHHHH
FILESAGDEKPVHEVCVSDFMIAKYEVTQGQWKQFMGNRPSNFRDCGDSCPVEQVSWNEV
HHHHCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHH
QQFIQRLNRQTGLQFRLPSEAEWEYACRSGGKQEKFCGGNDIDVLAWHHDNSDGRPHPVG
HHHHHHHHHHCCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
QKKPNGLGIYDMSGNVWEWVQDWFDTSYYSKSPRMNPQGPTTSSEKAVRGGCWDCEPKCI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHH
RASIRYWFAPNGRFSGLGFRLAHPTAVSVKHSGGKTDEQ
HHEEHEEECCCCCCCCCEEEEECCEEEEEECCCCCCCCC
>Mature Secondary Structure 
GTPSIKKHLYTLSALTWLTILLLPVICDAHDALLVPDELRQRSDIELVPVKGGCFQMGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCCCEEEECCCCHHHHHH
FILESAGDEKPVHEVCVSDFMIAKYEVTQGQWKQFMGNRPSNFRDCGDSCPVEQVSWNEV
HHHHCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHH
QQFIQRLNRQTGLQFRLPSEAEWEYACRSGGKQEKFCGGNDIDVLAWHHDNSDGRPHPVG
HHHHHHHHHHCCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
QKKPNGLGIYDMSGNVWEWVQDWFDTSYYSKSPRMNPQGPTTSSEKAVRGGCWDCEPKCI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHH
RASIRYWFAPNGRFSGLGFRLAHPTAVSVKHSGGKTDEQ
HHEEHEEECCCCCCCCCEEEEECCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]