Click here to switch to the map view.

The map label for this gene is yfbG [C]

Identifier: 189424205

GI number: 189424205

Start: 1189993

End: 1190931

Strand: Reverse

Name: yfbG [C]

Synonym: Glov_1140

Alternate gene names: 189424205

Gene position: 1190931-1189993 (Counterclockwise)

Preceding gene: 189424206

Following gene: 189424204

Centisome position: 30.4

GC content: 55.17

Gene sequence:

>939_bases
ATGCGTATTCTCGTCACCGGCGGCGCGGGCTTTCTGGGCAGTCACCTCTGTGAGCGGCTGCTCAATGAAGGCAATGACGT
CATCTGCCTGGACAACCTCTTTACCGGCAGCAAAGACAACATCATCCACCTGATGGACAACCATCGCTTTGAGCTGATCC
GTCACGACATCGTGGAACCGATCCTGCTGGAGGTGGACCGGATCTACAATCTGGCCTGTCCCGCTTCGCCGGTGCACTAC
CAGTACAACCCGGTCAAGACCGTCAAGACCAGCGTGATGGGGATGATCAACATGCTGGGGATGGCAAAACGGGTCAAGGC
CCGTATCCTGCAGGCCTCTACCTCGGAGGTCTACGGTGATCCCCAGGTCCACCCCCAGAAGGAGGAATACTGGGGCAACG
TCAACCCGATCGGTATTCGCAGCTGCTACGATGAAGGCAAGCGGGTAGCCGAGACCCTGATGATGGACTACCATCGCCAG
AACAAGGTTGATATCCGTATCATCAGGATCTTCAACACCTACGGCCCCCGCATGGCGGAAAACGACGGCAGGGTGGTATC
CAACTTCATGCTGCAGGCCCTGAAAAACGAAGACATTACGGTCTTCGGCGAAGGCAGGCAGACCCGCTCCTTCTGCTACG
TCAGCGACCTGATCGACGGCATGATCAGGATGATGGAAAATGAGCAGGACTTCATCGGCCCGGTCAATCTGGGGAACCCG
GTTGAAAACACCATCCTTGAATTTGCTGAAAAAATCATTACAATAACCGGCTCAAAATCAAAGATAATATACAAACCGCT
GCCTCAGGATGACCCGAAACAACGCAGACCGGACATCACCCTGGCGCAGGAGAAACTTGGTTGGCAGCCGTCCATAGACC
TTGAAACAGGCCTGAAGGCCACAGCGGACTACTTTGCAGCACGCTGTAACAGGGGTTGA

Upstream 100 bases:

>100_bases
AATAGAGGAGATTTGTTTTAACTTAGAGGGTAAACTTCATACAGATTGTGTATCCCCTCCATCCCTTGTATCCCTGTTAT
TGCTAGAAAGGTTTTGAATT

Downstream 100 bases:

>100_bases
TATGACCGGAATCCGCATCACACGCCGCACCTGGCTGATCCCAGCCATCTGCCTTGCCTTTATCCTGTTTTTCACGGTAT
TCGGCGAACGCGGTCTTTTG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRILVTGGAGFLGSHLCERLLNEGNDVICLDNLFTGSKDNIIHLMDNHRFELIRHDIVEPILLEVDRIYNLACPASPVHY
QYNPVKTVKTSVMGMINMLGMAKRVKARILQASTSEVYGDPQVHPQKEEYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NKVDIRIIRIFNTYGPRMAENDGRVVSNFMLQALKNEDITVFGEGRQTRSFCYVSDLIDGMIRMMENEQDFIGPVNLGNP
VENTILEFAEKIITITGSKSKIIYKPLPQDDPKQRRPDITLAQEKLGWQPSIDLETGLKATADYFAARCNRG

Sequences:

>Translated_312_residues
MRILVTGGAGFLGSHLCERLLNEGNDVICLDNLFTGSKDNIIHLMDNHRFELIRHDIVEPILLEVDRIYNLACPASPVHY
QYNPVKTVKTSVMGMINMLGMAKRVKARILQASTSEVYGDPQVHPQKEEYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NKVDIRIIRIFNTYGPRMAENDGRVVSNFMLQALKNEDITVFGEGRQTRSFCYVSDLIDGMIRMMENEQDFIGPVNLGNP
VENTILEFAEKIITITGSKSKIIYKPLPQDDPKQRRPDITLAQEKLGWQPSIDLETGLKATADYFAARCNRG
>Mature_312_residues
MRILVTGGAGFLGSHLCERLLNEGNDVICLDNLFTGSKDNIIHLMDNHRFELIRHDIVEPILLEVDRIYNLACPASPVHY
QYNPVKTVKTSVMGMINMLGMAKRVKARILQASTSEVYGDPQVHPQKEEYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NKVDIRIIRIFNTYGPRMAENDGRVVSNFMLQALKNEDITVFGEGRQTRSFCYVSDLIDGMIRMMENEQDFIGPVNLGNP
VENTILEFAEKIITITGSKSKIIYKPLPQDDPKQRRPDITLAQEKLGWQPSIDLETGLKATADYFAARCNRG

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=304, Percent_Identity=58.8815789473684, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=25.1552795031056, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1788589, Length=338, Percent_Identity=25.4437869822485, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786974, Length=318, Percent_Identity=25.1572327044025, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI48994969, Length=341, Percent_Identity=24.3401759530792, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=23.9644970414201, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788365, Length=329, Percent_Identity=24.0121580547112, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=311, Percent_Identity=58.5209003215434, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71982035, Length=332, Percent_Identity=26.2048192771084, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=339, Percent_Identity=25.9587020648968, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=320, Percent_Identity=24.6875, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=341, Percent_Identity=23.4604105571848, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=61.6613418530351, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=24.7787610619469, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35440; Mature: 35440

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGFLGSHLCERLLNEGNDVICLDNLFTGSKDNIIHLMDNHRFELIRHDIVEP
CEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ILLEVDRIYNLACPASPVHYQYNPVKTVKTSVMGMINMLGMAKRVKARILQASTSEVYGD
HHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQVHPQKEEYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQNKVDIRIIRIFNTYGPRMAE
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCC
NDGRVVSNFMLQALKNEDITVFGEGRQTRSFCYVSDLIDGMIRMMENEQDFIGPVNLGNP
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VENTILEFAEKIITITGSKSKIIYKPLPQDDPKQRRPDITLAQEKLGWQPSIDLETGLKA
HHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCCCEEHHHHCCCCCCCCHHCCCHH
TADYFAARCNRG
HHHHHHHHCCCC
>Mature Secondary Structure
MRILVTGGAGFLGSHLCERLLNEGNDVICLDNLFTGSKDNIIHLMDNHRFELIRHDIVEP
CEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ILLEVDRIYNLACPASPVHYQYNPVKTVKTSVMGMINMLGMAKRVKARILQASTSEVYGD
HHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQVHPQKEEYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQNKVDIRIIRIFNTYGPRMAE
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCC
NDGRVVSNFMLQALKNEDITVFGEGRQTRSFCYVSDLIDGMIRMMENEQDFIGPVNLGNP
CCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VENTILEFAEKIITITGSKSKIIYKPLPQDDPKQRRPDITLAQEKLGWQPSIDLETGLKA
HHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCCCEEHHHHCCCCCCCCHHCCCHH
TADYFAARCNRG
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]