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The map label for this gene is argS [H]

Identifier: 189424202

GI number: 189424202

Start: 1187812

End: 1189506

Strand: Reverse

Name: argS [H]

Synonym: Glov_1137

Alternate gene names: 189424202

Gene position: 1189506-1187812 (Counterclockwise)

Preceding gene: 189424203

Following gene: 189424201

Centisome position: 30.36

GC content: 59.06

Gene sequence:

>1695_bases
ATGATCCGTCAGAAACTTGCTGTACTGGTAACCCAAGCCCTTGCCTCTGCCCGCAATGCAGGCGTCCTTTGTTCAGAACT
GTTCCCTGATGTCGTTATCGGCACCCCTGCCCAGGAAGCCCACGGTGATTTTGCCTGCAACATCGCCCTGCAACTGGCAA
AACCGGAACGCAAGTCCCCCCGCCAGGTGGCTGAAAGTGTACTGCTGCACCTCCAGGACACTGACGGACTGATTCGCCGG
GCTGAAATAGCCGGTCCGGGCTTCATCAACTTTTTTATTGCTCCGTCTGCCTGGCAACAGTGCCTGCCACTGATTGAACA
GGCCGGCCCGGCCTACGGCACCACGGACAGCGGCGCCGGTCGCAAGGCGCAGGTTGAGTTTGTCAGTGCCAACCCCACCG
GGCCACTCCATATCGGCCATGGTCGGGGTGCTGCCATCGGTGATGTGCTCTGCCGCCTGCTGGCTGCAACCGGCTGGCAG
GTCACCCGTGAATTTTATTACAACGACGCCGGTGCCCAGATCAGCAACCTGGCCCTGTCGGTCCAGGCCCGCTGCCTCGG
GATTGAAACCGACGACCCGCGCTGGCCTGCAGATGGCTACCAGGGAGAGTACATCAAAGAGGTGGCAACGGCCTACCTTG
CCGGGGAGACCGTTGTTGCCGGAGACCAGCAGGTCACTGCCAGCGGCGACCCGGACGATCTGGATGCCATCCGGCGTTTT
GCCGTTGCAGCCCTGCGCAGGGAACAGGATCAGGATCTGCAGGCCTTTGATGTCCGCTTTGACCACTACTTCCTCGAATC
AAGCCTCTACTCTGACGGCAAGGTGGAGGCAGCAGTGCAGCAGATGATTGCCAATGGTCACACCTATGAGCAGGAGGGAG
CACTCTGGCTGCGCACCACCGATTTTGGTGATGACAAGGACCGGGTCATGCGCAAGACCGACGGCGGCTACACCTATTTC
GTACCGGATGTGGCCTACCATCTGGACAAATGGCAGCGCGGCTTCCTGCGGGTCGTCAATGAGCAGGGAGCCGACCACCA
CAGTACCATCACCCGGGTGCGGGCCGGCCTGCAGGCCCTGAACGCCGGTATTCCCAAGGGCTGGCCGGAATACGTCCTGC
ATCAGATGGTCACCGTCATGCGGGGTGGCGAAGAGGTCAAGATCTCCAAGCGGGCCGGCAGCTATGTCACCCTGCGGGAT
CTGATCGACGAGGTCGGTCGTGACGCCACCCGCTTCTTCTTTGTAATGCGTAAGCCCGACTCGCAACTGGTCTTTGACAT
AGACCTTGCCAAACAGCAATCACTGGACAACCCGGTCTACTATATCCAGTATGCCCATGCCCGTATCTGCAGCATCTTTG
AGAATGCGGCAGACAAAGGCATCCACCTGCCTGATCAGACGCCAGACGCAGCTGTTCTCGCTCAACTTGAGACCCCTGAA
GAACTGCGTCTGATCAAGTGGCTTGAAAGCCTGCCGGAAACCGTTGATGACGCGGCACAGGAGTTTGAACCGCACAAGAT
CGTCTATTACCTGACCGAACTGGCAGGCCAGTTCCACAGCTATTACAACAAGTCCAAGGTAGTGACGGAAGACACCTCAC
TGAGTATCGCACGACTCTACCTGTTGGCCCGCACCAGGCAGGTTATACAAAACGCCCTCACCCTGCTGGGCGTATCAGCC
CCGGAAAAGATGTAG

Upstream 100 bases:

>100_bases
GTGCCCGCTGCCCCGATTTTTCACGGGATATCACCATAAAAGATCAGGACACTGCCGAGCTGCCTGCGACCAATGATTCT
TCCAAGGAACCTCCCCAACA

Downstream 100 bases:

>100_bases
GAGGTCAGCCATGCGGATCGACTATAGTGAGCCACGGCAATCCTACGGCTCCAGCAGTTCAAGCAGTGGCGGCAGTCCAC
GCAAGGCAGACAGATCATCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MIRQKLAVLVTQALASARNAGVLCSELFPDVVIGTPAQEAHGDFACNIALQLAKPERKSPRQVAESVLLHLQDTDGLIRR
AEIAGPGFINFFIAPSAWQQCLPLIEQAGPAYGTTDSGAGRKAQVEFVSANPTGPLHIGHGRGAAIGDVLCRLLAATGWQ
VTREFYYNDAGAQISNLALSVQARCLGIETDDPRWPADGYQGEYIKEVATAYLAGETVVAGDQQVTASGDPDDLDAIRRF
AVAALRREQDQDLQAFDVRFDHYFLESSLYSDGKVEAAVQQMIANGHTYEQEGALWLRTTDFGDDKDRVMRKTDGGYTYF
VPDVAYHLDKWQRGFLRVVNEQGADHHSTITRVRAGLQALNAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRD
LIDEVGRDATRFFFVMRKPDSQLVFDIDLAKQQSLDNPVYYIQYAHARICSIFENAADKGIHLPDQTPDAAVLAQLETPE
ELRLIKWLESLPETVDDAAQEFEPHKIVYYLTELAGQFHSYYNKSKVVTEDTSLSIARLYLLARTRQVIQNALTLLGVSA
PEKM

Sequences:

>Translated_564_residues
MIRQKLAVLVTQALASARNAGVLCSELFPDVVIGTPAQEAHGDFACNIALQLAKPERKSPRQVAESVLLHLQDTDGLIRR
AEIAGPGFINFFIAPSAWQQCLPLIEQAGPAYGTTDSGAGRKAQVEFVSANPTGPLHIGHGRGAAIGDVLCRLLAATGWQ
VTREFYYNDAGAQISNLALSVQARCLGIETDDPRWPADGYQGEYIKEVATAYLAGETVVAGDQQVTASGDPDDLDAIRRF
AVAALRREQDQDLQAFDVRFDHYFLESSLYSDGKVEAAVQQMIANGHTYEQEGALWLRTTDFGDDKDRVMRKTDGGYTYF
VPDVAYHLDKWQRGFLRVVNEQGADHHSTITRVRAGLQALNAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRD
LIDEVGRDATRFFFVMRKPDSQLVFDIDLAKQQSLDNPVYYIQYAHARICSIFENAADKGIHLPDQTPDAAVLAQLETPE
ELRLIKWLESLPETVDDAAQEFEPHKIVYYLTELAGQFHSYYNKSKVVTEDTSLSIARLYLLARTRQVIQNALTLLGVSA
PEKM
>Mature_564_residues
MIRQKLAVLVTQALASARNAGVLCSELFPDVVIGTPAQEAHGDFACNIALQLAKPERKSPRQVAESVLLHLQDTDGLIRR
AEIAGPGFINFFIAPSAWQQCLPLIEQAGPAYGTTDSGAGRKAQVEFVSANPTGPLHIGHGRGAAIGDVLCRLLAATGWQ
VTREFYYNDAGAQISNLALSVQARCLGIETDDPRWPADGYQGEYIKEVATAYLAGETVVAGDQQVTASGDPDDLDAIRRF
AVAALRREQDQDLQAFDVRFDHYFLESSLYSDGKVEAAVQQMIANGHTYEQEGALWLRTTDFGDDKDRVMRKTDGGYTYF
VPDVAYHLDKWQRGFLRVVNEQGADHHSTITRVRAGLQALNAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRD
LIDEVGRDATRFFFVMRKPDSQLVFDIDLAKQQSLDNPVYYIQYAHARICSIFENAADKGIHLPDQTPDAAVLAQLETPE
ELRLIKWLESLPETVDDAAQEFEPHKIVYYLTELAGQFHSYYNKSKVVTEDTSLSIARLYLLARTRQVIQNALTLLGVSA
PEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=599, Percent_Identity=25.0417362270451, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1788184, Length=567, Percent_Identity=27.1604938271605, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71985061, Length=588, Percent_Identity=24.1496598639456, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320548, Length=530, Percent_Identity=24.1509433962264, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321883, Length=560, Percent_Identity=24.8214285714286, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=24.223602484472, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62508; Mature: 62508

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQKLAVLVTQALASARNAGVLCSELFPDVVIGTPAQEAHGDFACNIALQLAKPERKSP
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEECCCCHHHCCCEEEEEEEEECCCCCCCH
RQVAESVLLHLQDTDGLIRRAEIAGPGFINFFIAPSAWQQCLPLIEQAGPAYGTTDSGAG
HHHHHHHHHHCCCCCCHHEEHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCC
RKAQVEFVSANPTGPLHIGHGRGAAIGDVLCRLLAATGWQVTREFYYNDAGAQISNLALS
CEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHEE
VQARCLGIETDDPRWPADGYQGEYIKEVATAYLAGETVVAGDQQVTASGDPDDLDAIRRF
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHHHHHH
AVAALRREQDQDLQAFDVRFDHYFLESSLYSDGKVEAAVQQMIANGHTYEQEGALWLRTT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEC
DFGDDKDRVMRKTDGGYTYFVPDVAYHLDKWQRGFLRVVNEQGADHHSTITRVRAGLQAL
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLIDEVGRDATRFFFVMRKPD
HCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEEECCC
SQLVFDIDLAKQQSLDNPVYYIQYAHARICSIFENAADKGIHLPDQTPDAAVLAQLETPE
CCEEEEEEHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCHH
ELRLIKWLESLPETVDDAAQEFEPHKIVYYLTELAGQFHSYYNKSKVVTEDTSLSIARLY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
LLARTRQVIQNALTLLGVSAPEKM
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIRQKLAVLVTQALASARNAGVLCSELFPDVVIGTPAQEAHGDFACNIALQLAKPERKSP
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEECCCCHHHCCCEEEEEEEEECCCCCCCH
RQVAESVLLHLQDTDGLIRRAEIAGPGFINFFIAPSAWQQCLPLIEQAGPAYGTTDSGAG
HHHHHHHHHHCCCCCCHHEEHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCC
RKAQVEFVSANPTGPLHIGHGRGAAIGDVLCRLLAATGWQVTREFYYNDAGAQISNLALS
CEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHEE
VQARCLGIETDDPRWPADGYQGEYIKEVATAYLAGETVVAGDQQVTASGDPDDLDAIRRF
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHHHHHH
AVAALRREQDQDLQAFDVRFDHYFLESSLYSDGKVEAAVQQMIANGHTYEQEGALWLRTT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEC
DFGDDKDRVMRKTDGGYTYFVPDVAYHLDKWQRGFLRVVNEQGADHHSTITRVRAGLQAL
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLIDEVGRDATRFFFVMRKPD
HCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEEECCC
SQLVFDIDLAKQQSLDNPVYYIQYAHARICSIFENAADKGIHLPDQTPDAAVLAQLETPE
CCEEEEEEHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCHH
ELRLIKWLESLPETVDDAAQEFEPHKIVYYLTELAGQFHSYYNKSKVVTEDTSLSIARLY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
LLARTRQVIQNALTLLGVSAPEKM
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA