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The map label for this gene is dinB [H]

Identifier: 189424136

GI number: 189424136

Start: 1115728

End: 1116957

Strand: Reverse

Name: dinB [H]

Synonym: Glov_1070

Alternate gene names: 189424136

Gene position: 1116957-1115728 (Counterclockwise)

Preceding gene: 189424137

Following gene: 189424131

Centisome position: 28.51

GC content: 58.7

Gene sequence:

>1230_bases
ATGGACAGGGCTATCCTTCATATCGATATGAATGCGTTTTTCGCCTCGGTGGAACAGCAGGCCAACCCCGACCTGCAGGG
CAAACCGGTTGCGGTTGTCGGCTCAGGTCATCGCACGGTCATCACCACCGCCTCCTACGAGGCCCGCCGTTTTGGGGTCA
AGACCGGTATGGCCATCTGGGAGGGCAGACGGGCCTGCCCCGAACTGATCATCATTGTCGGTGACAACAAAAAATATACC
CATGCCTCCCGGCAGATCATTGGCATGATGCGGCAGTACACCCCCCTGGTGGAGGTATTTTCCATTGATGAGGCCTTCCT
TGATGTAACCCATTCCCGCGCCCTGTTTGGCTCTGCTGAAACCATTGCCCATCAACTAAAAGCACGGATCAGGCAGGAAC
TGGGCCTGACCTGCTCCGTCGGCATCGCCCCGAACAAGCTGCTTGCCAAACTGGCCAGTGACATGCAGAAGCCTGACGGT
TTAACCGTAATCGCGCCGGATCAGATCAAGGCGGTGCTGGAATCAGTTACCATCGGCGATCTCTGCGGCATCGGCAAGAA
GCTGGAACGCCGGTTGAACCTGCTGGGGATCAAGAGTTGCGGACAGCTGGGGCGTTTCCCGGAAGAGCTGCTCAGCAGAA
AATTCGGCATCATCGGCCCCAGGCTCAGAGAGATGGGACAGGGGATCGACGACAGCCCGGTACTGGCGACGGAGGGGGAT
GAGCAGGTCAAGAGTGTCGGCCACTCCATGACGCTGCACAAGGATATAGACACACGGCAGGATATCCTGCGCTACCTGCT
GCAACTGGCAGAGATGGTGGGGAGACGGGCCCGGCGCTACGGCGTGAGCGGCAAGACGGTCAGCATCTACATCCGCTTTG
CCGACTTTTTCACCAACATCCAGAAGCAGATCACCCTGGACAGCTACATCAACCTCAGTAACGACATCTACCGGAGCGCG
GTCCGCTTGCTGGACAGCATGGAGCTCAGCCAGCCGGTCAGGCTGCTGGGGGTCTGCCTGAGCAACCTGGAATACCAGGA
ACAGCAGCCGTCCCTGTTTGCGGAAGAGCGCAGGAAAGAGCAGCTGACCAGGGCCATGGATGCGGTTAATGACCGCTTCG
GCGATTTCAAGCTCACCTTCGGCAGCATGCTGAACACGGAAGAAAAGGGATCGCACGTTATCTCGCCGGCCTGGCGGCCC
GAGGGGATCAGAAGCGTGGTGGTGACGTAA

Upstream 100 bases:

>100_bases
CAGACCGTAAAGAGGCATCCGTCGCCGGTCCTTTCTCACCCTTGGGCTGTTGAAGATCACGCTTGACTTCGCGTGGTAGT
CATTTGGTAACCTCTGTTCC

Downstream 100 bases:

>100_bases
TCTGAAAGCAGATCAACATCCGCTCAGGGCGGCCTACGGCAAGGCCCGCAGCAGGGTCCGCAGACTCAAGAGGCAGACCA
GGCTCCCCACCAGTATGGTC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDRAILHIDMNAFFASVEQQANPDLQGKPVAVVGSGHRTVITTASYEARRFGVKTGMAIWEGRRACPELIIIVGDNKKYT
HASRQIIGMMRQYTPLVEVFSIDEAFLDVTHSRALFGSAETIAHQLKARIRQELGLTCSVGIAPNKLLAKLASDMQKPDG
LTVIAPDQIKAVLESVTIGDLCGIGKKLERRLNLLGIKSCGQLGRFPEELLSRKFGIIGPRLREMGQGIDDSPVLATEGD
EQVKSVGHSMTLHKDIDTRQDILRYLLQLAEMVGRRARRYGVSGKTVSIYIRFADFFTNIQKQITLDSYINLSNDIYRSA
VRLLDSMELSQPVRLLGVCLSNLEYQEQQPSLFAEERRKEQLTRAMDAVNDRFGDFKLTFGSMLNTEEKGSHVISPAWRP
EGIRSVVVT

Sequences:

>Translated_409_residues
MDRAILHIDMNAFFASVEQQANPDLQGKPVAVVGSGHRTVITTASYEARRFGVKTGMAIWEGRRACPELIIIVGDNKKYT
HASRQIIGMMRQYTPLVEVFSIDEAFLDVTHSRALFGSAETIAHQLKARIRQELGLTCSVGIAPNKLLAKLASDMQKPDG
LTVIAPDQIKAVLESVTIGDLCGIGKKLERRLNLLGIKSCGQLGRFPEELLSRKFGIIGPRLREMGQGIDDSPVLATEGD
EQVKSVGHSMTLHKDIDTRQDILRYLLQLAEMVGRRARRYGVSGKTVSIYIRFADFFTNIQKQITLDSYINLSNDIYRSA
VRLLDSMELSQPVRLLGVCLSNLEYQEQQPSLFAEERRKEQLTRAMDAVNDRFGDFKLTFGSMLNTEEKGSHVISPAWRP
EGIRSVVVT
>Mature_409_residues
MDRAILHIDMNAFFASVEQQANPDLQGKPVAVVGSGHRTVITTASYEARRFGVKTGMAIWEGRRACPELIIIVGDNKKYT
HASRQIIGMMRQYTPLVEVFSIDEAFLDVTHSRALFGSAETIAHQLKARIRQELGLTCSVGIAPNKLLAKLASDMQKPDG
LTVIAPDQIKAVLESVTIGDLCGIGKKLERRLNLLGIKSCGQLGRFPEELLSRKFGIIGPRLREMGQGIDDSPVLATEGD
EQVKSVGHSMTLHKDIDTRQDILRYLLQLAEMVGRRARRYGVSGKTVSIYIRFADFFTNIQKQITLDSYINLSNDIYRSA
VRLLDSMELSQPVRLLGVCLSNLEYQEQQPSLFAEERRKEQLTRAMDAVNDRFGDFKLTFGSMLNTEEKGSHVISPAWRP
EGIRSVVVT

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=393, Percent_Identity=27.4809160305344, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI84043967, Length=417, Percent_Identity=27.0983213429257, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI7706681, Length=418, Percent_Identity=27.0334928229665, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI7705344, Length=110, Percent_Identity=40, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI5729982, Length=122, Percent_Identity=36.8852459016393, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=34.4729344729345, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787432, Length=396, Percent_Identity=28.030303030303, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193205700, Length=409, Percent_Identity=28.361858190709, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=242, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193205702, Length=346, Percent_Identity=26.0115606936416, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=39.5161290322581, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21355641, Length=320, Percent_Identity=30.625, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24644984, Length=320, Percent_Identity=30.625, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=26.5243902439024, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668444, Length=160, Percent_Identity=31.875, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45637; Mature: 45637

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAILHIDMNAFFASVEQQANPDLQGKPVAVVGSGHRTVITTASYEARRFGVKTGMAIW
CCCEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHCHHHH
EGRRACPELIIIVGDNKKYTHASRQIIGMMRQYTPLVEVFSIDEAFLDVTHSRALFGSAE
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TIAHQLKARIRQELGLTCSVGIAPNKLLAKLASDMQKPDGLTVIAPDQIKAVLESVTIGD
HHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCHHH
LCGIGKKLERRLNLLGIKSCGQLGRFPEELLSRKFGIIGPRLREMGQGIDDSPVLATEGD
HHCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEECCCH
EQVKSVGHSMTLHKDIDTRQDILRYLLQLAEMVGRRARRYGVSGKTVSIYIRFADFFTNI
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHH
QKQITLDSYINLSNDIYRSAVRLLDSMELSQPVRLLGVCLSNLEYQEQQPSLFAEERRKE
HHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
QLTRAMDAVNDRFGDFKLTFGSMLNTEEKGSHVISPAWRPEGIRSVVVT
HHHHHHHHHHHCCCCEEEEHHHHHCCCCCCCEECCCCCCCCCCCEEECC
>Mature Secondary Structure
MDRAILHIDMNAFFASVEQQANPDLQGKPVAVVGSGHRTVITTASYEARRFGVKTGMAIW
CCCEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHCHHHH
EGRRACPELIIIVGDNKKYTHASRQIIGMMRQYTPLVEVFSIDEAFLDVTHSRALFGSAE
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TIAHQLKARIRQELGLTCSVGIAPNKLLAKLASDMQKPDGLTVIAPDQIKAVLESVTIGD
HHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCHHH
LCGIGKKLERRLNLLGIKSCGQLGRFPEELLSRKFGIIGPRLREMGQGIDDSPVLATEGD
HHCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCEEECCCH
EQVKSVGHSMTLHKDIDTRQDILRYLLQLAEMVGRRARRYGVSGKTVSIYIRFADFFTNI
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHH
QKQITLDSYINLSNDIYRSAVRLLDSMELSQPVRLLGVCLSNLEYQEQQPSLFAEERRKE
HHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHH
QLTRAMDAVNDRFGDFKLTFGSMLNTEEKGSHVISPAWRPEGIRSVVVT
HHHHHHHHHHHCCCCEEEEHHHHHCCCCCCCEECCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA